Deprecated (16384): The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 73
 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php. [CORE/src/Core/functions.php, line 311]
Code Context


        trigger_error($message, E_USER_DEPRECATED);

    }
$message = 'The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 73
 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php.'
$stackFrame = (int) 1
$trace = [
	(int) 0 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ServerRequest.php',
		'line' => (int) 2421,
		'function' => 'deprecationWarning',
		'args' => [
			(int) 0 => 'The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead.'
		]
	],
	(int) 1 => [
		'file' => '/home/brlfuser/public_html/src/Controller/ArtileDetailController.php',
		'line' => (int) 73,
		'function' => 'offsetGet',
		'class' => 'Cake\Http\ServerRequest',
		'object' => object(Cake\Http\ServerRequest) {},
		'type' => '->',
		'args' => [
			(int) 0 => 'catslug'
		]
	],
	(int) 2 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Controller/Controller.php',
		'line' => (int) 610,
		'function' => 'printArticle',
		'class' => 'App\Controller\ArtileDetailController',
		'object' => object(App\Controller\ArtileDetailController) {},
		'type' => '->',
		'args' => []
	],
	(int) 3 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ActionDispatcher.php',
		'line' => (int) 120,
		'function' => 'invokeAction',
		'class' => 'Cake\Controller\Controller',
		'object' => object(App\Controller\ArtileDetailController) {},
		'type' => '->',
		'args' => []
	],
	(int) 4 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ActionDispatcher.php',
		'line' => (int) 94,
		'function' => '_invoke',
		'class' => 'Cake\Http\ActionDispatcher',
		'object' => object(Cake\Http\ActionDispatcher) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(App\Controller\ArtileDetailController) {}
		]
	],
	(int) 5 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/BaseApplication.php',
		'line' => (int) 235,
		'function' => 'dispatch',
		'class' => 'Cake\Http\ActionDispatcher',
		'object' => object(Cake\Http\ActionDispatcher) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {}
		]
	],
	(int) 6 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php',
		'line' => (int) 65,
		'function' => '__invoke',
		'class' => 'Cake\Http\BaseApplication',
		'object' => object(App\Application) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {},
			(int) 2 => object(Cake\Http\Runner) {}
		]
	],
	(int) 7 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Routing/Middleware/RoutingMiddleware.php',
		'line' => (int) 162,
		'function' => '__invoke',
		'class' => 'Cake\Http\Runner',
		'object' => object(Cake\Http\Runner) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {}
		]
	],
	(int) 8 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php',
		'line' => (int) 65,
		'function' => '__invoke',
		'class' => 'Cake\Routing\Middleware\RoutingMiddleware',
		'object' => object(Cake\Routing\Middleware\RoutingMiddleware) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {},
			(int) 2 => object(Cake\Http\Runner) {}
		]
	],
	(int) 9 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Routing/Middleware/AssetMiddleware.php',
		'line' => (int) 88,
		'function' => '__invoke',
		'class' => 'Cake\Http\Runner',
		'object' => object(Cake\Http\Runner) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {}
		]
	],
	(int) 10 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php',
		'line' => (int) 65,
		'function' => '__invoke',
		'class' => 'Cake\Routing\Middleware\AssetMiddleware',
		'object' => object(Cake\Routing\Middleware\AssetMiddleware) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {},
			(int) 2 => object(Cake\Http\Runner) {}
		]
	],
	(int) 11 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Middleware/ErrorHandlerMiddleware.php',
		'line' => (int) 96,
		'function' => '__invoke',
		'class' => 'Cake\Http\Runner',
		'object' => object(Cake\Http\Runner) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {}
		]
	],
	(int) 12 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php',
		'line' => (int) 65,
		'function' => '__invoke',
		'class' => 'Cake\Error\Middleware\ErrorHandlerMiddleware',
		'object' => object(Cake\Error\Middleware\ErrorHandlerMiddleware) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {},
			(int) 2 => object(Cake\Http\Runner) {}
		]
	],
	(int) 13 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php',
		'line' => (int) 51,
		'function' => '__invoke',
		'class' => 'Cake\Http\Runner',
		'object' => object(Cake\Http\Runner) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {}
		]
	],
	(int) 14 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Server.php',
		'line' => (int) 98,
		'function' => 'run',
		'class' => 'Cake\Http\Runner',
		'object' => object(Cake\Http\Runner) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\MiddlewareQueue) {},
			(int) 1 => object(Cake\Http\ServerRequest) {},
			(int) 2 => object(Cake\Http\Response) {}
		]
	],
	(int) 15 => [
		'file' => '/home/brlfuser/public_html/webroot/index.php',
		'line' => (int) 39,
		'function' => 'run',
		'class' => 'Cake\Http\Server',
		'object' => object(Cake\Http\Server) {},
		'type' => '->',
		'args' => []
	]
]
$frame = [
	'file' => '/home/brlfuser/public_html/src/Controller/ArtileDetailController.php',
	'line' => (int) 73,
	'function' => 'offsetGet',
	'class' => 'Cake\Http\ServerRequest',
	'object' => object(Cake\Http\ServerRequest) {
		trustProxy => false
		[protected] params => [
			[maximum depth reached]
		]
		[protected] data => [[maximum depth reached]]
		[protected] query => [[maximum depth reached]]
		[protected] cookies => [
			[maximum depth reached]
		]
		[protected] _environment => [
			[maximum depth reached]
		]
		[protected] url => 'latest-news-updates/dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970/print'
		[protected] base => ''
		[protected] webroot => '/'
		[protected] here => '/latest-news-updates/dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970/print'
		[protected] trustedProxies => [[maximum depth reached]]
		[protected] _input => null
		[protected] _detectors => [
			[maximum depth reached]
		]
		[protected] _detectorCache => [
			[maximum depth reached]
		]
		[protected] stream => object(Zend\Diactoros\PhpInputStream) {}
		[protected] uri => object(Zend\Diactoros\Uri) {}
		[protected] session => object(Cake\Http\Session) {}
		[protected] attributes => [[maximum depth reached]]
		[protected] emulatedAttributes => [
			[maximum depth reached]
		]
		[protected] uploadedFiles => [[maximum depth reached]]
		[protected] protocol => null
		[protected] requestTarget => null
		[private] deprecatedProperties => [
			[maximum depth reached]
		]
	},
	'type' => '->',
	'args' => [
		(int) 0 => 'catslug'
	]
]
deprecationWarning - CORE/src/Core/functions.php, line 311
Cake\Http\ServerRequest::offsetGet() - CORE/src/Http/ServerRequest.php, line 2421
App\Controller\ArtileDetailController::printArticle() - APP/Controller/ArtileDetailController.php, line 73
Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 610
Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 120
Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94
Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51
Cake\Http\Server::run() - CORE/src/Http/Server.php, line 98

Deprecated (16384): The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 74
 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php. [CORE/src/Core/functions.php, line 311]
Code Context


        trigger_error($message, E_USER_DEPRECATED);

    }
$message = 'The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 74
 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php.'
$stackFrame = (int) 1
$trace = [
	(int) 0 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ServerRequest.php',
		'line' => (int) 2421,
		'function' => 'deprecationWarning',
		'args' => [
			(int) 0 => 'The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead.'
		]
	],
	(int) 1 => [
		'file' => '/home/brlfuser/public_html/src/Controller/ArtileDetailController.php',
		'line' => (int) 74,
		'function' => 'offsetGet',
		'class' => 'Cake\Http\ServerRequest',
		'object' => object(Cake\Http\ServerRequest) {},
		'type' => '->',
		'args' => [
			(int) 0 => 'artileslug'
		]
	],
	(int) 2 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Controller/Controller.php',
		'line' => (int) 610,
		'function' => 'printArticle',
		'class' => 'App\Controller\ArtileDetailController',
		'object' => object(App\Controller\ArtileDetailController) {},
		'type' => '->',
		'args' => []
	],
	(int) 3 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ActionDispatcher.php',
		'line' => (int) 120,
		'function' => 'invokeAction',
		'class' => 'Cake\Controller\Controller',
		'object' => object(App\Controller\ArtileDetailController) {},
		'type' => '->',
		'args' => []
	],
	(int) 4 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ActionDispatcher.php',
		'line' => (int) 94,
		'function' => '_invoke',
		'class' => 'Cake\Http\ActionDispatcher',
		'object' => object(Cake\Http\ActionDispatcher) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(App\Controller\ArtileDetailController) {}
		]
	],
	(int) 5 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/BaseApplication.php',
		'line' => (int) 235,
		'function' => 'dispatch',
		'class' => 'Cake\Http\ActionDispatcher',
		'object' => object(Cake\Http\ActionDispatcher) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {}
		]
	],
	(int) 6 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php',
		'line' => (int) 65,
		'function' => '__invoke',
		'class' => 'Cake\Http\BaseApplication',
		'object' => object(App\Application) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {},
			(int) 2 => object(Cake\Http\Runner) {}
		]
	],
	(int) 7 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Routing/Middleware/RoutingMiddleware.php',
		'line' => (int) 162,
		'function' => '__invoke',
		'class' => 'Cake\Http\Runner',
		'object' => object(Cake\Http\Runner) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {}
		]
	],
	(int) 8 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php',
		'line' => (int) 65,
		'function' => '__invoke',
		'class' => 'Cake\Routing\Middleware\RoutingMiddleware',
		'object' => object(Cake\Routing\Middleware\RoutingMiddleware) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {},
			(int) 2 => object(Cake\Http\Runner) {}
		]
	],
	(int) 9 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Routing/Middleware/AssetMiddleware.php',
		'line' => (int) 88,
		'function' => '__invoke',
		'class' => 'Cake\Http\Runner',
		'object' => object(Cake\Http\Runner) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {}
		]
	],
	(int) 10 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php',
		'line' => (int) 65,
		'function' => '__invoke',
		'class' => 'Cake\Routing\Middleware\AssetMiddleware',
		'object' => object(Cake\Routing\Middleware\AssetMiddleware) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {},
			(int) 2 => object(Cake\Http\Runner) {}
		]
	],
	(int) 11 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Middleware/ErrorHandlerMiddleware.php',
		'line' => (int) 96,
		'function' => '__invoke',
		'class' => 'Cake\Http\Runner',
		'object' => object(Cake\Http\Runner) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {}
		]
	],
	(int) 12 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php',
		'line' => (int) 65,
		'function' => '__invoke',
		'class' => 'Cake\Error\Middleware\ErrorHandlerMiddleware',
		'object' => object(Cake\Error\Middleware\ErrorHandlerMiddleware) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {},
			(int) 2 => object(Cake\Http\Runner) {}
		]
	],
	(int) 13 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php',
		'line' => (int) 51,
		'function' => '__invoke',
		'class' => 'Cake\Http\Runner',
		'object' => object(Cake\Http\Runner) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\ServerRequest) {},
			(int) 1 => object(Cake\Http\Response) {}
		]
	],
	(int) 14 => [
		'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Server.php',
		'line' => (int) 98,
		'function' => 'run',
		'class' => 'Cake\Http\Runner',
		'object' => object(Cake\Http\Runner) {},
		'type' => '->',
		'args' => [
			(int) 0 => object(Cake\Http\MiddlewareQueue) {},
			(int) 1 => object(Cake\Http\ServerRequest) {},
			(int) 2 => object(Cake\Http\Response) {}
		]
	],
	(int) 15 => [
		'file' => '/home/brlfuser/public_html/webroot/index.php',
		'line' => (int) 39,
		'function' => 'run',
		'class' => 'Cake\Http\Server',
		'object' => object(Cake\Http\Server) {},
		'type' => '->',
		'args' => []
	]
]
$frame = [
	'file' => '/home/brlfuser/public_html/src/Controller/ArtileDetailController.php',
	'line' => (int) 74,
	'function' => 'offsetGet',
	'class' => 'Cake\Http\ServerRequest',
	'object' => object(Cake\Http\ServerRequest) {
		trustProxy => false
		[protected] params => [
			[maximum depth reached]
		]
		[protected] data => [[maximum depth reached]]
		[protected] query => [[maximum depth reached]]
		[protected] cookies => [
			[maximum depth reached]
		]
		[protected] _environment => [
			[maximum depth reached]
		]
		[protected] url => 'latest-news-updates/dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970/print'
		[protected] base => ''
		[protected] webroot => '/'
		[protected] here => '/latest-news-updates/dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970/print'
		[protected] trustedProxies => [[maximum depth reached]]
		[protected] _input => null
		[protected] _detectors => [
			[maximum depth reached]
		]
		[protected] _detectorCache => [
			[maximum depth reached]
		]
		[protected] stream => object(Zend\Diactoros\PhpInputStream) {}
		[protected] uri => object(Zend\Diactoros\Uri) {}
		[protected] session => object(Cake\Http\Session) {}
		[protected] attributes => [[maximum depth reached]]
		[protected] emulatedAttributes => [
			[maximum depth reached]
		]
		[protected] uploadedFiles => [[maximum depth reached]]
		[protected] protocol => null
		[protected] requestTarget => null
		[private] deprecatedProperties => [
			[maximum depth reached]
		]
	},
	'type' => '->',
	'args' => [
		(int) 0 => 'artileslug'
	]
]
deprecationWarning - CORE/src/Core/functions.php, line 311
Cake\Http\ServerRequest::offsetGet() - CORE/src/Http/ServerRequest.php, line 2421
App\Controller\ArtileDetailController::printArticle() - APP/Controller/ArtileDetailController.php, line 74
Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 610
Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 120
Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94
Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51
Cake\Http\Server::run() - CORE/src/Http/Server.php, line 98

Warning (512): Unable to emit headers. Headers sent in file=/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php line=853 [CORE/src/Http/ResponseEmitter.php, line 48]
Code Context
            if (Configure::read('debug')) {

                trigger_error($message, E_USER_WARNING);

            } else {
$response = object(Cake\Http\Response) {

	'status' => (int) 200,
	'contentType' => 'text/html',
	'headers' => [
		'Content-Type' => [
			[maximum depth reached]
		]
	],
	'file' => null,
	'fileRange' => [],
	'cookies' => object(Cake\Http\Cookie\CookieCollection) {},
	'cacheDirectives' => [],
	'body' => '<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN"
        "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
<html xmlns="http://www.w3.org/1999/xhtml">
<head>
    <link rel="canonical" href="https://im4change.in/<pre class="cake-error"><a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f56cb8c344f-trace').style.display = (document.getElementById('cakeErr67f56cb8c344f-trace').style.display == 'none' ? '' : 'none');"><b>Notice</b> (8)</a>: Undefined variable: urlPrefix [<b>APP/Template/Layout/printlayout.ctp</b>, line <b>8</b>]<div id="cakeErr67f56cb8c344f-trace" class="cake-stack-trace" style="display: none;"><a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f56cb8c344f-code').style.display = (document.getElementById('cakeErr67f56cb8c344f-code').style.display == 'none' ? '' : 'none')">Code</a> <a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f56cb8c344f-context').style.display = (document.getElementById('cakeErr67f56cb8c344f-context').style.display == 'none' ? '' : 'none')">Context</a><pre id="cakeErr67f56cb8c344f-code" class="cake-code-dump" style="display: none;"><code><span style="color: #000000"><span style="color: #0000BB"></span><span style="color: #007700">&lt;</span><span style="color: #0000BB">head</span><span style="color: #007700">&gt;
</span></span></code>
<span class="code-highlight"><code><span style="color: #000000">&nbsp;&nbsp;&nbsp;&nbsp;&lt;link&nbsp;rel="canonical"&nbsp;href="<span style="color: #0000BB">&lt;?php&nbsp;</span><span style="color: #007700">echo&nbsp;</span><span style="color: #0000BB">Configure</span><span style="color: #007700">::</span><span style="color: #0000BB">read</span><span style="color: #007700">(</span><span style="color: #DD0000">'SITE_URL'</span><span style="color: #007700">);&nbsp;</span><span style="color: #0000BB">?&gt;&lt;?php&nbsp;</span><span style="color: #007700">echo&nbsp;</span><span style="color: #0000BB">$urlPrefix</span><span style="color: #007700">;</span><span style="color: #0000BB">?&gt;&lt;?php&nbsp;</span><span style="color: #007700">echo&nbsp;</span><span style="color: #0000BB">$article_current</span><span style="color: #007700">-&gt;</span><span style="color: #0000BB">category</span><span style="color: #007700">-&gt;</span><span style="color: #0000BB">slug</span><span style="color: #007700">;&nbsp;</span><span style="color: #0000BB">?&gt;</span>/<span style="color: #0000BB">&lt;?php&nbsp;</span><span style="color: #007700">echo&nbsp;</span><span style="color: #0000BB">$article_current</span><span style="color: #007700">-&gt;</span><span style="color: #0000BB">seo_url</span><span style="color: #007700">;&nbsp;</span><span style="color: #0000BB">?&gt;</span>.html"/&gt;
</span></code></span>
<code><span style="color: #000000"><span style="color: #0000BB">&nbsp;&nbsp;&nbsp;&nbsp;</span><span style="color: #007700">&lt;</span><span style="color: #0000BB">meta&nbsp;http</span><span style="color: #007700">-</span><span style="color: #0000BB">equiv</span><span style="color: #007700">=</span><span style="color: #DD0000">"Content-Type"&nbsp;</span><span style="color: #0000BB">content</span><span style="color: #007700">=</span><span style="color: #DD0000">"text/html;&nbsp;charset=utf-8"</span><span style="color: #007700">/&gt;
</span></span></code></pre><pre id="cakeErr67f56cb8c344f-context" class="cake-context" style="display: none;">$viewFile = &#039;/home/brlfuser/public_html/src/Template/Layout/printlayout.ctp&#039;
$dataForView = [
	&#039;article_current&#039; =&gt; object(App\Model\Entity\Article) {

		&#039;id&#039; =&gt; (int) 22816,
		&#039;title&#039; =&gt; &#039;Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney&#039;,
		&#039;subheading&#039; =&gt; &#039;&#039;,
		&#039;description&#039; =&gt; &#039;&lt;div align=&quot;justify&quot;&gt;
-Down to Earth
&lt;/div&gt;
&lt;p align=&quot;justify&quot;&gt;
&lt;br /&gt;
&lt;em&gt;Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year&lt;/em&gt;
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.&lt;br /&gt;
 
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
&lt;img src=&quot;tinymce/uploaded/Dengue.JPG&quot; alt=&quot;Dengue&quot; width=&quot;483&quot; height=&quot;235&quot; /&gt;&lt;br /&gt;
Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India&#039;s National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Serotype shifts
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar&#039;s studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Deadly combination
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &amp;quot;We are taking steps to control the vector,&amp;quot; says Dhariwal.&lt;br /&gt;
 
&lt;/p&gt;&#039;,
		&#039;credit_writer&#039; =&gt; &#039;Down to Earth, 8 October, 2013, http://www.downtoearth.org.in/content/dengue-grips-delhi-virus-strain-circulating-year-more-deadly&#039;,
		&#039;article_img&#039; =&gt; &#039;&#039;,
		&#039;article_img_thumb&#039; =&gt; &#039;&#039;,
		&#039;status&#039; =&gt; (int) 1,
		&#039;show_on_home&#039; =&gt; (int) 1,
		&#039;lang&#039; =&gt; &#039;EN&#039;,
		&#039;category_id&#039; =&gt; (int) 16,
		&#039;tag_keyword&#039; =&gt; &#039;&#039;,
		&#039;seo_url&#039; =&gt; &#039;dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970&#039;,
		&#039;meta_title&#039; =&gt; null,
		&#039;meta_keywords&#039; =&gt; null,
		&#039;meta_description&#039; =&gt; null,
		&#039;noindex&#039; =&gt; (int) 0,
		&#039;publish_date&#039; =&gt; object(Cake\I18n\FrozenDate) {},
		&#039;most_visit_section_id&#039; =&gt; null,
		&#039;article_big_img&#039; =&gt; null,
		&#039;liveid&#039; =&gt; (int) 22970,
		&#039;created&#039; =&gt; object(Cake\I18n\FrozenTime) {},
		&#039;modified&#039; =&gt; object(Cake\I18n\FrozenTime) {},
		&#039;edate&#039; =&gt; &#039;&#039;,
		&#039;tags&#039; =&gt; [
			[maximum depth reached]
		],
		&#039;category&#039; =&gt; object(App\Model\Entity\Category) {},
		&#039;[new]&#039; =&gt; false,
		&#039;[accessible]&#039; =&gt; [
			[maximum depth reached]
		],
		&#039;[dirty]&#039; =&gt; [[maximum depth reached]],
		&#039;[original]&#039; =&gt; [[maximum depth reached]],
		&#039;[virtual]&#039; =&gt; [[maximum depth reached]],
		&#039;[hasErrors]&#039; =&gt; false,
		&#039;[errors]&#039; =&gt; [[maximum depth reached]],
		&#039;[invalid]&#039; =&gt; [[maximum depth reached]],
		&#039;[repository]&#039; =&gt; &#039;Articles&#039;
	
	},
	&#039;articleid&#039; =&gt; (int) 22816,
	&#039;metaTitle&#039; =&gt; &#039;LATEST NEWS UPDATES | Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney&#039;,
	&#039;metaKeywords&#039; =&gt; &#039;dengue,Health&#039;,
	&#039;metaDesc&#039; =&gt; &#039;
-Down to Earth



Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year


More than 2,916 people have already been reported affected by dengue this year in Delhi....&#039;,
	&#039;disp&#039; =&gt; &#039;&lt;div align=&quot;justify&quot;&gt;-Down to Earth&lt;/div&gt;&lt;p align=&quot;justify&quot;&gt;&lt;br /&gt;&lt;em&gt;Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year&lt;/em&gt;&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.&lt;br /&gt; &lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;&lt;img src=&quot;https://im4change.in/siteadmin/tinymce/uploaded/Dengue.JPG&quot; alt=&quot;Dengue&quot; width=&quot;483&quot; height=&quot;235&quot; /&gt;&lt;br /&gt;Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India&#039;s National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Serotype shifts&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar&#039;s studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Deadly combination&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &amp;quot;We are taking steps to control the vector,&amp;quot; says Dhariwal.&lt;br /&gt; &lt;/p&gt;&#039;,
	&#039;lang&#039; =&gt; &#039;English&#039;,
	&#039;SITE_URL&#039; =&gt; &#039;https://im4change.in/&#039;,
	&#039;site_title&#039; =&gt; &#039;im4change&#039;,
	&#039;adminprix&#039; =&gt; &#039;admin&#039;
]
$article_current = object(App\Model\Entity\Article) {

	&#039;id&#039; =&gt; (int) 22816,
	&#039;title&#039; =&gt; &#039;Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney&#039;,
	&#039;subheading&#039; =&gt; &#039;&#039;,
	&#039;description&#039; =&gt; &#039;&lt;div align=&quot;justify&quot;&gt;
-Down to Earth
&lt;/div&gt;
&lt;p align=&quot;justify&quot;&gt;
&lt;br /&gt;
&lt;em&gt;Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year&lt;/em&gt;
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.&lt;br /&gt;
 
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
&lt;img src=&quot;tinymce/uploaded/Dengue.JPG&quot; alt=&quot;Dengue&quot; width=&quot;483&quot; height=&quot;235&quot; /&gt;&lt;br /&gt;
Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India&#039;s National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Serotype shifts
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar&#039;s studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Deadly combination
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &amp;quot;We are taking steps to control the vector,&amp;quot; says Dhariwal.&lt;br /&gt;
 
&lt;/p&gt;&#039;,
	&#039;credit_writer&#039; =&gt; &#039;Down to Earth, 8 October, 2013, http://www.downtoearth.org.in/content/dengue-grips-delhi-virus-strain-circulating-year-more-deadly&#039;,
	&#039;article_img&#039; =&gt; &#039;&#039;,
	&#039;article_img_thumb&#039; =&gt; &#039;&#039;,
	&#039;status&#039; =&gt; (int) 1,
	&#039;show_on_home&#039; =&gt; (int) 1,
	&#039;lang&#039; =&gt; &#039;EN&#039;,
	&#039;category_id&#039; =&gt; (int) 16,
	&#039;tag_keyword&#039; =&gt; &#039;&#039;,
	&#039;seo_url&#039; =&gt; &#039;dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970&#039;,
	&#039;meta_title&#039; =&gt; null,
	&#039;meta_keywords&#039; =&gt; null,
	&#039;meta_description&#039; =&gt; null,
	&#039;noindex&#039; =&gt; (int) 0,
	&#039;publish_date&#039; =&gt; object(Cake\I18n\FrozenDate) {},
	&#039;most_visit_section_id&#039; =&gt; null,
	&#039;article_big_img&#039; =&gt; null,
	&#039;liveid&#039; =&gt; (int) 22970,
	&#039;created&#039; =&gt; object(Cake\I18n\FrozenTime) {},
	&#039;modified&#039; =&gt; object(Cake\I18n\FrozenTime) {},
	&#039;edate&#039; =&gt; &#039;&#039;,
	&#039;tags&#039; =&gt; [
		(int) 0 =&gt; object(Cake\ORM\Entity) {},
		(int) 1 =&gt; object(Cake\ORM\Entity) {}
	],
	&#039;category&#039; =&gt; object(App\Model\Entity\Category) {},
	&#039;[new]&#039; =&gt; false,
	&#039;[accessible]&#039; =&gt; [
		&#039;*&#039; =&gt; true,
		&#039;id&#039; =&gt; false
	],
	&#039;[dirty]&#039; =&gt; [],
	&#039;[original]&#039; =&gt; [],
	&#039;[virtual]&#039; =&gt; [],
	&#039;[hasErrors]&#039; =&gt; false,
	&#039;[errors]&#039; =&gt; [],
	&#039;[invalid]&#039; =&gt; [],
	&#039;[repository]&#039; =&gt; &#039;Articles&#039;

}
$articleid = (int) 22816
$metaTitle = &#039;LATEST NEWS UPDATES | Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney&#039;
$metaKeywords = &#039;dengue,Health&#039;
$metaDesc = &#039;
-Down to Earth



Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year


More than 2,916 people have already been reported affected by dengue this year in Delhi....&#039;
$disp = &#039;&lt;div align=&quot;justify&quot;&gt;-Down to Earth&lt;/div&gt;&lt;p align=&quot;justify&quot;&gt;&lt;br /&gt;&lt;em&gt;Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year&lt;/em&gt;&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.&lt;br /&gt; &lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;&lt;img src=&quot;https://im4change.in/siteadmin/tinymce/uploaded/Dengue.JPG&quot; alt=&quot;Dengue&quot; width=&quot;483&quot; height=&quot;235&quot; /&gt;&lt;br /&gt;Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India&#039;s National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Serotype shifts&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar&#039;s studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Deadly combination&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &amp;quot;We are taking steps to control the vector,&amp;quot; says Dhariwal.&lt;br /&gt; &lt;/p&gt;&#039;
$lang = &#039;English&#039;
$SITE_URL = &#039;https://im4change.in/&#039;
$site_title = &#039;im4change&#039;
$adminprix = &#039;admin&#039;</pre><pre class="stack-trace">include - APP/Template/Layout/printlayout.ctp, line 8
Cake\View\View::_evaluate() - CORE/src/View/View.php, line 1413
Cake\View\View::_render() - CORE/src/View/View.php, line 1374
Cake\View\View::renderLayout() - CORE/src/View/View.php, line 927
Cake\View\View::render() - CORE/src/View/View.php, line 885
Cake\Controller\Controller::render() - CORE/src/Controller/Controller.php, line 791
Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 126
Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94
Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51</pre></div></pre>latest-news-updates/dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970.html"/>
    <meta http-equiv="Content-Type" content="text/html; charset=utf-8"/>
    <link href="https://im4change.in/css/control.css" rel="stylesheet" type="text/css"
          media="all"/>
    <title>LATEST NEWS UPDATES | Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney | Im4change.org</title>
    <meta name="description" content="
-Down to Earth



Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year


More than 2,916 people have already been reported affected by dengue this year in Delhi...."/>
    <script src="https://im4change.in/js/jquery-1.10.2.js"></script>
    <script type="text/javascript" src="https://im4change.in/js/jquery-migrate.min.js"></script>
    <script language="javascript" type="text/javascript">

        $(document).ready(function () {
            var img = $("img")[0]; // Get my img elem
            var pic_real_width, pic_real_height;
            $("<img/>") // Make in memory copy of image to avoid css issues
                .attr("src", $(img).attr("src"))
                .load(function () {
                    pic_real_width = this.width;   // Note: $(this).width() will not
                    pic_real_height = this.height; // work for in memory images.
                });
        });
    </script>
    <style type="text/css">
        @media screen {
            div.divFooter {
                display: block;
            }
        }

        @media print {
            .printbutton {
                display: none !important;
            }
        }
    </style>
</head>
<body>
<table cellpadding="0" cellspacing="0" border="0" width="98%" align="center">
    <tr>
        <td class="top_bg">
            <div class="divFooter">
                <img src="https://im4change.in/images/logo1.jpg" height="59" border="0"
                     alt="Resource centre on India's rural distress" style="padding-top:14px;"/>
            </div>

        </td>
    </tr>
    <tr>
        <td id="topspace">&nbsp;</td>
    </tr>

    <tr id="topspace">
        <td>&nbsp;</td>
    </tr>
    <tr>
        <td height="50" style="border-bottom:1px solid #000; padding-top:10px;" class="printbutton">
            <form><input type="button" value=" Print this page "
                         onclick="window.print();return false;"/></form>
        </td>
    </tr>

    <tr>
        <td width="100%">
            <h1 class="news_headlines" style="font-style:normal">
                <strong>Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney</strong></h1>
        </td>
    </tr>
    <tr>
        <td width="100%" style="font-family:Arial, 'Segoe Script', 'Segoe UI', sans-serif, serif"><font size="3">
                <div align="justify">-Down to Earth</div><p align="justify"><br /><em>Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year</em></p><p align="justify">More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.<br /> </p><p align="justify"><img src="https://im4change.in/siteadmin/tinymce/uploaded/Dengue.JPG" alt="Dengue" width="483" height="235" /><br />Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India's National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.</p><p align="justify">But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.</p><p align="justify">Serotype shifts</p><p align="justify">During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.</p><p align="justify">DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.</p><p align="justify">Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar's studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.</p><p align="justify">Deadly combination</p><p align="justify">Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.</p><p align="justify">These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.</p><p align="justify">Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.</p><p align="justify">Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &quot;We are taking steps to control the vector,&quot; says Dhariwal.<br /> </p>               </font>
        </td>
    </tr>
    <tr>
        <td>&nbsp;</td>
    </tr>

    <tr>
        <td height="50" style="border-top:1px solid #000; border-bottom:1px solid #000;padding-top:10px;">
            <form><input type="button" value=" Print this page "
                         onclick="window.print();return false;"/></form>
        </td>
    </tr>
</table></body>
</html>'

}
$maxBufferLength = (int) 8192
$file = '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php'
$line = (int) 853
$message = 'Unable to emit headers. Headers sent in file=/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php line=853'
Cake\Http\ResponseEmitter::emit() - CORE/src/Http/ResponseEmitter.php, line 48
Cake\Http\Server::emit() - CORE/src/Http/Server.php, line 141
[main] - ROOT/webroot/index.php, line 39

Warning (2): Cannot modify header information - headers already sent by (output started at /home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php:853) [CORE/src/Http/ResponseEmitter.php, line 148]
Code Context
            $response->getStatusCode(),

            ($reasonPhrase ? ' ' . $reasonPhrase : '')

        ));
$response = object(Cake\Http\Response) {

	'status' => (int) 200,
	'contentType' => 'text/html',
	'headers' => [
		'Content-Type' => [
			[maximum depth reached]
		]
	],
	'file' => null,
	'fileRange' => [],
	'cookies' => object(Cake\Http\Cookie\CookieCollection) {},
	'cacheDirectives' => [],
	'body' => '<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN"
        "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
<html xmlns="http://www.w3.org/1999/xhtml">
<head>
    <link rel="canonical" href="https://im4change.in/<pre class="cake-error"><a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f56cb8c344f-trace').style.display = (document.getElementById('cakeErr67f56cb8c344f-trace').style.display == 'none' ? '' : 'none');"><b>Notice</b> (8)</a>: Undefined variable: urlPrefix [<b>APP/Template/Layout/printlayout.ctp</b>, line <b>8</b>]<div id="cakeErr67f56cb8c344f-trace" class="cake-stack-trace" style="display: none;"><a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f56cb8c344f-code').style.display = (document.getElementById('cakeErr67f56cb8c344f-code').style.display == 'none' ? '' : 'none')">Code</a> <a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f56cb8c344f-context').style.display = (document.getElementById('cakeErr67f56cb8c344f-context').style.display == 'none' ? '' : 'none')">Context</a><pre id="cakeErr67f56cb8c344f-code" class="cake-code-dump" style="display: none;"><code><span style="color: #000000"><span style="color: #0000BB"></span><span style="color: #007700">&lt;</span><span style="color: #0000BB">head</span><span style="color: #007700">&gt;
</span></span></code>
<span class="code-highlight"><code><span style="color: #000000">&nbsp;&nbsp;&nbsp;&nbsp;&lt;link&nbsp;rel="canonical"&nbsp;href="<span style="color: #0000BB">&lt;?php&nbsp;</span><span style="color: #007700">echo&nbsp;</span><span style="color: #0000BB">Configure</span><span style="color: #007700">::</span><span style="color: #0000BB">read</span><span style="color: #007700">(</span><span style="color: #DD0000">'SITE_URL'</span><span style="color: #007700">);&nbsp;</span><span style="color: #0000BB">?&gt;&lt;?php&nbsp;</span><span style="color: #007700">echo&nbsp;</span><span style="color: #0000BB">$urlPrefix</span><span style="color: #007700">;</span><span style="color: #0000BB">?&gt;&lt;?php&nbsp;</span><span style="color: #007700">echo&nbsp;</span><span style="color: #0000BB">$article_current</span><span style="color: #007700">-&gt;</span><span style="color: #0000BB">category</span><span style="color: #007700">-&gt;</span><span style="color: #0000BB">slug</span><span style="color: #007700">;&nbsp;</span><span style="color: #0000BB">?&gt;</span>/<span style="color: #0000BB">&lt;?php&nbsp;</span><span style="color: #007700">echo&nbsp;</span><span style="color: #0000BB">$article_current</span><span style="color: #007700">-&gt;</span><span style="color: #0000BB">seo_url</span><span style="color: #007700">;&nbsp;</span><span style="color: #0000BB">?&gt;</span>.html"/&gt;
</span></code></span>
<code><span style="color: #000000"><span style="color: #0000BB">&nbsp;&nbsp;&nbsp;&nbsp;</span><span style="color: #007700">&lt;</span><span style="color: #0000BB">meta&nbsp;http</span><span style="color: #007700">-</span><span style="color: #0000BB">equiv</span><span style="color: #007700">=</span><span style="color: #DD0000">"Content-Type"&nbsp;</span><span style="color: #0000BB">content</span><span style="color: #007700">=</span><span style="color: #DD0000">"text/html;&nbsp;charset=utf-8"</span><span style="color: #007700">/&gt;
</span></span></code></pre><pre id="cakeErr67f56cb8c344f-context" class="cake-context" style="display: none;">$viewFile = &#039;/home/brlfuser/public_html/src/Template/Layout/printlayout.ctp&#039;
$dataForView = [
	&#039;article_current&#039; =&gt; object(App\Model\Entity\Article) {

		&#039;id&#039; =&gt; (int) 22816,
		&#039;title&#039; =&gt; &#039;Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney&#039;,
		&#039;subheading&#039; =&gt; &#039;&#039;,
		&#039;description&#039; =&gt; &#039;&lt;div align=&quot;justify&quot;&gt;
-Down to Earth
&lt;/div&gt;
&lt;p align=&quot;justify&quot;&gt;
&lt;br /&gt;
&lt;em&gt;Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year&lt;/em&gt;
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.&lt;br /&gt;
 
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
&lt;img src=&quot;tinymce/uploaded/Dengue.JPG&quot; alt=&quot;Dengue&quot; width=&quot;483&quot; height=&quot;235&quot; /&gt;&lt;br /&gt;
Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India&#039;s National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Serotype shifts
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar&#039;s studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Deadly combination
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &amp;quot;We are taking steps to control the vector,&amp;quot; says Dhariwal.&lt;br /&gt;
 
&lt;/p&gt;&#039;,
		&#039;credit_writer&#039; =&gt; &#039;Down to Earth, 8 October, 2013, http://www.downtoearth.org.in/content/dengue-grips-delhi-virus-strain-circulating-year-more-deadly&#039;,
		&#039;article_img&#039; =&gt; &#039;&#039;,
		&#039;article_img_thumb&#039; =&gt; &#039;&#039;,
		&#039;status&#039; =&gt; (int) 1,
		&#039;show_on_home&#039; =&gt; (int) 1,
		&#039;lang&#039; =&gt; &#039;EN&#039;,
		&#039;category_id&#039; =&gt; (int) 16,
		&#039;tag_keyword&#039; =&gt; &#039;&#039;,
		&#039;seo_url&#039; =&gt; &#039;dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970&#039;,
		&#039;meta_title&#039; =&gt; null,
		&#039;meta_keywords&#039; =&gt; null,
		&#039;meta_description&#039; =&gt; null,
		&#039;noindex&#039; =&gt; (int) 0,
		&#039;publish_date&#039; =&gt; object(Cake\I18n\FrozenDate) {},
		&#039;most_visit_section_id&#039; =&gt; null,
		&#039;article_big_img&#039; =&gt; null,
		&#039;liveid&#039; =&gt; (int) 22970,
		&#039;created&#039; =&gt; object(Cake\I18n\FrozenTime) {},
		&#039;modified&#039; =&gt; object(Cake\I18n\FrozenTime) {},
		&#039;edate&#039; =&gt; &#039;&#039;,
		&#039;tags&#039; =&gt; [
			[maximum depth reached]
		],
		&#039;category&#039; =&gt; object(App\Model\Entity\Category) {},
		&#039;[new]&#039; =&gt; false,
		&#039;[accessible]&#039; =&gt; [
			[maximum depth reached]
		],
		&#039;[dirty]&#039; =&gt; [[maximum depth reached]],
		&#039;[original]&#039; =&gt; [[maximum depth reached]],
		&#039;[virtual]&#039; =&gt; [[maximum depth reached]],
		&#039;[hasErrors]&#039; =&gt; false,
		&#039;[errors]&#039; =&gt; [[maximum depth reached]],
		&#039;[invalid]&#039; =&gt; [[maximum depth reached]],
		&#039;[repository]&#039; =&gt; &#039;Articles&#039;
	
	},
	&#039;articleid&#039; =&gt; (int) 22816,
	&#039;metaTitle&#039; =&gt; &#039;LATEST NEWS UPDATES | Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney&#039;,
	&#039;metaKeywords&#039; =&gt; &#039;dengue,Health&#039;,
	&#039;metaDesc&#039; =&gt; &#039;
-Down to Earth



Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year


More than 2,916 people have already been reported affected by dengue this year in Delhi....&#039;,
	&#039;disp&#039; =&gt; &#039;&lt;div align=&quot;justify&quot;&gt;-Down to Earth&lt;/div&gt;&lt;p align=&quot;justify&quot;&gt;&lt;br /&gt;&lt;em&gt;Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year&lt;/em&gt;&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.&lt;br /&gt; &lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;&lt;img src=&quot;https://im4change.in/siteadmin/tinymce/uploaded/Dengue.JPG&quot; alt=&quot;Dengue&quot; width=&quot;483&quot; height=&quot;235&quot; /&gt;&lt;br /&gt;Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India&#039;s National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Serotype shifts&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar&#039;s studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Deadly combination&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &amp;quot;We are taking steps to control the vector,&amp;quot; says Dhariwal.&lt;br /&gt; &lt;/p&gt;&#039;,
	&#039;lang&#039; =&gt; &#039;English&#039;,
	&#039;SITE_URL&#039; =&gt; &#039;https://im4change.in/&#039;,
	&#039;site_title&#039; =&gt; &#039;im4change&#039;,
	&#039;adminprix&#039; =&gt; &#039;admin&#039;
]
$article_current = object(App\Model\Entity\Article) {

	&#039;id&#039; =&gt; (int) 22816,
	&#039;title&#039; =&gt; &#039;Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney&#039;,
	&#039;subheading&#039; =&gt; &#039;&#039;,
	&#039;description&#039; =&gt; &#039;&lt;div align=&quot;justify&quot;&gt;
-Down to Earth
&lt;/div&gt;
&lt;p align=&quot;justify&quot;&gt;
&lt;br /&gt;
&lt;em&gt;Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year&lt;/em&gt;
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.&lt;br /&gt;
 
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
&lt;img src=&quot;tinymce/uploaded/Dengue.JPG&quot; alt=&quot;Dengue&quot; width=&quot;483&quot; height=&quot;235&quot; /&gt;&lt;br /&gt;
Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India&#039;s National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Serotype shifts
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar&#039;s studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Deadly combination
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &amp;quot;We are taking steps to control the vector,&amp;quot; says Dhariwal.&lt;br /&gt;
 
&lt;/p&gt;&#039;,
	&#039;credit_writer&#039; =&gt; &#039;Down to Earth, 8 October, 2013, http://www.downtoearth.org.in/content/dengue-grips-delhi-virus-strain-circulating-year-more-deadly&#039;,
	&#039;article_img&#039; =&gt; &#039;&#039;,
	&#039;article_img_thumb&#039; =&gt; &#039;&#039;,
	&#039;status&#039; =&gt; (int) 1,
	&#039;show_on_home&#039; =&gt; (int) 1,
	&#039;lang&#039; =&gt; &#039;EN&#039;,
	&#039;category_id&#039; =&gt; (int) 16,
	&#039;tag_keyword&#039; =&gt; &#039;&#039;,
	&#039;seo_url&#039; =&gt; &#039;dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970&#039;,
	&#039;meta_title&#039; =&gt; null,
	&#039;meta_keywords&#039; =&gt; null,
	&#039;meta_description&#039; =&gt; null,
	&#039;noindex&#039; =&gt; (int) 0,
	&#039;publish_date&#039; =&gt; object(Cake\I18n\FrozenDate) {},
	&#039;most_visit_section_id&#039; =&gt; null,
	&#039;article_big_img&#039; =&gt; null,
	&#039;liveid&#039; =&gt; (int) 22970,
	&#039;created&#039; =&gt; object(Cake\I18n\FrozenTime) {},
	&#039;modified&#039; =&gt; object(Cake\I18n\FrozenTime) {},
	&#039;edate&#039; =&gt; &#039;&#039;,
	&#039;tags&#039; =&gt; [
		(int) 0 =&gt; object(Cake\ORM\Entity) {},
		(int) 1 =&gt; object(Cake\ORM\Entity) {}
	],
	&#039;category&#039; =&gt; object(App\Model\Entity\Category) {},
	&#039;[new]&#039; =&gt; false,
	&#039;[accessible]&#039; =&gt; [
		&#039;*&#039; =&gt; true,
		&#039;id&#039; =&gt; false
	],
	&#039;[dirty]&#039; =&gt; [],
	&#039;[original]&#039; =&gt; [],
	&#039;[virtual]&#039; =&gt; [],
	&#039;[hasErrors]&#039; =&gt; false,
	&#039;[errors]&#039; =&gt; [],
	&#039;[invalid]&#039; =&gt; [],
	&#039;[repository]&#039; =&gt; &#039;Articles&#039;

}
$articleid = (int) 22816
$metaTitle = &#039;LATEST NEWS UPDATES | Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney&#039;
$metaKeywords = &#039;dengue,Health&#039;
$metaDesc = &#039;
-Down to Earth



Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year


More than 2,916 people have already been reported affected by dengue this year in Delhi....&#039;
$disp = &#039;&lt;div align=&quot;justify&quot;&gt;-Down to Earth&lt;/div&gt;&lt;p align=&quot;justify&quot;&gt;&lt;br /&gt;&lt;em&gt;Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year&lt;/em&gt;&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.&lt;br /&gt; &lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;&lt;img src=&quot;https://im4change.in/siteadmin/tinymce/uploaded/Dengue.JPG&quot; alt=&quot;Dengue&quot; width=&quot;483&quot; height=&quot;235&quot; /&gt;&lt;br /&gt;Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India&#039;s National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Serotype shifts&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar&#039;s studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Deadly combination&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &amp;quot;We are taking steps to control the vector,&amp;quot; says Dhariwal.&lt;br /&gt; &lt;/p&gt;&#039;
$lang = &#039;English&#039;
$SITE_URL = &#039;https://im4change.in/&#039;
$site_title = &#039;im4change&#039;
$adminprix = &#039;admin&#039;</pre><pre class="stack-trace">include - APP/Template/Layout/printlayout.ctp, line 8
Cake\View\View::_evaluate() - CORE/src/View/View.php, line 1413
Cake\View\View::_render() - CORE/src/View/View.php, line 1374
Cake\View\View::renderLayout() - CORE/src/View/View.php, line 927
Cake\View\View::render() - CORE/src/View/View.php, line 885
Cake\Controller\Controller::render() - CORE/src/Controller/Controller.php, line 791
Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 126
Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94
Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51</pre></div></pre>latest-news-updates/dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970.html"/>
    <meta http-equiv="Content-Type" content="text/html; charset=utf-8"/>
    <link href="https://im4change.in/css/control.css" rel="stylesheet" type="text/css"
          media="all"/>
    <title>LATEST NEWS UPDATES | Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney | Im4change.org</title>
    <meta name="description" content="
-Down to Earth



Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year


More than 2,916 people have already been reported affected by dengue this year in Delhi...."/>
    <script src="https://im4change.in/js/jquery-1.10.2.js"></script>
    <script type="text/javascript" src="https://im4change.in/js/jquery-migrate.min.js"></script>
    <script language="javascript" type="text/javascript">

        $(document).ready(function () {
            var img = $("img")[0]; // Get my img elem
            var pic_real_width, pic_real_height;
            $("<img/>") // Make in memory copy of image to avoid css issues
                .attr("src", $(img).attr("src"))
                .load(function () {
                    pic_real_width = this.width;   // Note: $(this).width() will not
                    pic_real_height = this.height; // work for in memory images.
                });
        });
    </script>
    <style type="text/css">
        @media screen {
            div.divFooter {
                display: block;
            }
        }

        @media print {
            .printbutton {
                display: none !important;
            }
        }
    </style>
</head>
<body>
<table cellpadding="0" cellspacing="0" border="0" width="98%" align="center">
    <tr>
        <td class="top_bg">
            <div class="divFooter">
                <img src="https://im4change.in/images/logo1.jpg" height="59" border="0"
                     alt="Resource centre on India's rural distress" style="padding-top:14px;"/>
            </div>

        </td>
    </tr>
    <tr>
        <td id="topspace">&nbsp;</td>
    </tr>

    <tr id="topspace">
        <td>&nbsp;</td>
    </tr>
    <tr>
        <td height="50" style="border-bottom:1px solid #000; padding-top:10px;" class="printbutton">
            <form><input type="button" value=" Print this page "
                         onclick="window.print();return false;"/></form>
        </td>
    </tr>

    <tr>
        <td width="100%">
            <h1 class="news_headlines" style="font-style:normal">
                <strong>Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney</strong></h1>
        </td>
    </tr>
    <tr>
        <td width="100%" style="font-family:Arial, 'Segoe Script', 'Segoe UI', sans-serif, serif"><font size="3">
                <div align="justify">-Down to Earth</div><p align="justify"><br /><em>Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year</em></p><p align="justify">More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.<br /> </p><p align="justify"><img src="https://im4change.in/siteadmin/tinymce/uploaded/Dengue.JPG" alt="Dengue" width="483" height="235" /><br />Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India's National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.</p><p align="justify">But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.</p><p align="justify">Serotype shifts</p><p align="justify">During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.</p><p align="justify">DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.</p><p align="justify">Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar's studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.</p><p align="justify">Deadly combination</p><p align="justify">Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.</p><p align="justify">These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.</p><p align="justify">Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.</p><p align="justify">Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &quot;We are taking steps to control the vector,&quot; says Dhariwal.<br /> </p>               </font>
        </td>
    </tr>
    <tr>
        <td>&nbsp;</td>
    </tr>

    <tr>
        <td height="50" style="border-top:1px solid #000; border-bottom:1px solid #000;padding-top:10px;">
            <form><input type="button" value=" Print this page "
                         onclick="window.print();return false;"/></form>
        </td>
    </tr>
</table></body>
</html>'

}
$reasonPhrase = 'OK'
header - [internal], line ??
Cake\Http\ResponseEmitter::emitStatusLine() - CORE/src/Http/ResponseEmitter.php, line 148
Cake\Http\ResponseEmitter::emit() - CORE/src/Http/ResponseEmitter.php, line 54
Cake\Http\Server::emit() - CORE/src/Http/Server.php, line 141
[main] - ROOT/webroot/index.php, line 39

Warning (2): Cannot modify header information - headers already sent by (output started at /home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php:853) [CORE/src/Http/ResponseEmitter.php, line 181]
Code Context
                    $value

                ), $first);

                $first = false;
$response = object(Cake\Http\Response) {

	'status' => (int) 200,
	'contentType' => 'text/html',
	'headers' => [
		'Content-Type' => [
			[maximum depth reached]
		]
	],
	'file' => null,
	'fileRange' => [],
	'cookies' => object(Cake\Http\Cookie\CookieCollection) {},
	'cacheDirectives' => [],
	'body' => '<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN"
        "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd">
<html xmlns="http://www.w3.org/1999/xhtml">
<head>
    <link rel="canonical" href="https://im4change.in/<pre class="cake-error"><a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f56cb8c344f-trace').style.display = (document.getElementById('cakeErr67f56cb8c344f-trace').style.display == 'none' ? '' : 'none');"><b>Notice</b> (8)</a>: Undefined variable: urlPrefix [<b>APP/Template/Layout/printlayout.ctp</b>, line <b>8</b>]<div id="cakeErr67f56cb8c344f-trace" class="cake-stack-trace" style="display: none;"><a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f56cb8c344f-code').style.display = (document.getElementById('cakeErr67f56cb8c344f-code').style.display == 'none' ? '' : 'none')">Code</a> <a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f56cb8c344f-context').style.display = (document.getElementById('cakeErr67f56cb8c344f-context').style.display == 'none' ? '' : 'none')">Context</a><pre id="cakeErr67f56cb8c344f-code" class="cake-code-dump" style="display: none;"><code><span style="color: #000000"><span style="color: #0000BB"></span><span style="color: #007700">&lt;</span><span style="color: #0000BB">head</span><span style="color: #007700">&gt;
</span></span></code>
<span class="code-highlight"><code><span style="color: #000000">&nbsp;&nbsp;&nbsp;&nbsp;&lt;link&nbsp;rel="canonical"&nbsp;href="<span style="color: #0000BB">&lt;?php&nbsp;</span><span style="color: #007700">echo&nbsp;</span><span style="color: #0000BB">Configure</span><span style="color: #007700">::</span><span style="color: #0000BB">read</span><span style="color: #007700">(</span><span style="color: #DD0000">'SITE_URL'</span><span style="color: #007700">);&nbsp;</span><span style="color: #0000BB">?&gt;&lt;?php&nbsp;</span><span style="color: #007700">echo&nbsp;</span><span style="color: #0000BB">$urlPrefix</span><span style="color: #007700">;</span><span style="color: #0000BB">?&gt;&lt;?php&nbsp;</span><span style="color: #007700">echo&nbsp;</span><span style="color: #0000BB">$article_current</span><span style="color: #007700">-&gt;</span><span style="color: #0000BB">category</span><span style="color: #007700">-&gt;</span><span style="color: #0000BB">slug</span><span style="color: #007700">;&nbsp;</span><span style="color: #0000BB">?&gt;</span>/<span style="color: #0000BB">&lt;?php&nbsp;</span><span style="color: #007700">echo&nbsp;</span><span style="color: #0000BB">$article_current</span><span style="color: #007700">-&gt;</span><span style="color: #0000BB">seo_url</span><span style="color: #007700">;&nbsp;</span><span style="color: #0000BB">?&gt;</span>.html"/&gt;
</span></code></span>
<code><span style="color: #000000"><span style="color: #0000BB">&nbsp;&nbsp;&nbsp;&nbsp;</span><span style="color: #007700">&lt;</span><span style="color: #0000BB">meta&nbsp;http</span><span style="color: #007700">-</span><span style="color: #0000BB">equiv</span><span style="color: #007700">=</span><span style="color: #DD0000">"Content-Type"&nbsp;</span><span style="color: #0000BB">content</span><span style="color: #007700">=</span><span style="color: #DD0000">"text/html;&nbsp;charset=utf-8"</span><span style="color: #007700">/&gt;
</span></span></code></pre><pre id="cakeErr67f56cb8c344f-context" class="cake-context" style="display: none;">$viewFile = &#039;/home/brlfuser/public_html/src/Template/Layout/printlayout.ctp&#039;
$dataForView = [
	&#039;article_current&#039; =&gt; object(App\Model\Entity\Article) {

		&#039;id&#039; =&gt; (int) 22816,
		&#039;title&#039; =&gt; &#039;Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney&#039;,
		&#039;subheading&#039; =&gt; &#039;&#039;,
		&#039;description&#039; =&gt; &#039;&lt;div align=&quot;justify&quot;&gt;
-Down to Earth
&lt;/div&gt;
&lt;p align=&quot;justify&quot;&gt;
&lt;br /&gt;
&lt;em&gt;Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year&lt;/em&gt;
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.&lt;br /&gt;
 
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
&lt;img src=&quot;tinymce/uploaded/Dengue.JPG&quot; alt=&quot;Dengue&quot; width=&quot;483&quot; height=&quot;235&quot; /&gt;&lt;br /&gt;
Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India&#039;s National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Serotype shifts
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar&#039;s studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Deadly combination
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &amp;quot;We are taking steps to control the vector,&amp;quot; says Dhariwal.&lt;br /&gt;
 
&lt;/p&gt;&#039;,
		&#039;credit_writer&#039; =&gt; &#039;Down to Earth, 8 October, 2013, http://www.downtoearth.org.in/content/dengue-grips-delhi-virus-strain-circulating-year-more-deadly&#039;,
		&#039;article_img&#039; =&gt; &#039;&#039;,
		&#039;article_img_thumb&#039; =&gt; &#039;&#039;,
		&#039;status&#039; =&gt; (int) 1,
		&#039;show_on_home&#039; =&gt; (int) 1,
		&#039;lang&#039; =&gt; &#039;EN&#039;,
		&#039;category_id&#039; =&gt; (int) 16,
		&#039;tag_keyword&#039; =&gt; &#039;&#039;,
		&#039;seo_url&#039; =&gt; &#039;dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970&#039;,
		&#039;meta_title&#039; =&gt; null,
		&#039;meta_keywords&#039; =&gt; null,
		&#039;meta_description&#039; =&gt; null,
		&#039;noindex&#039; =&gt; (int) 0,
		&#039;publish_date&#039; =&gt; object(Cake\I18n\FrozenDate) {},
		&#039;most_visit_section_id&#039; =&gt; null,
		&#039;article_big_img&#039; =&gt; null,
		&#039;liveid&#039; =&gt; (int) 22970,
		&#039;created&#039; =&gt; object(Cake\I18n\FrozenTime) {},
		&#039;modified&#039; =&gt; object(Cake\I18n\FrozenTime) {},
		&#039;edate&#039; =&gt; &#039;&#039;,
		&#039;tags&#039; =&gt; [
			[maximum depth reached]
		],
		&#039;category&#039; =&gt; object(App\Model\Entity\Category) {},
		&#039;[new]&#039; =&gt; false,
		&#039;[accessible]&#039; =&gt; [
			[maximum depth reached]
		],
		&#039;[dirty]&#039; =&gt; [[maximum depth reached]],
		&#039;[original]&#039; =&gt; [[maximum depth reached]],
		&#039;[virtual]&#039; =&gt; [[maximum depth reached]],
		&#039;[hasErrors]&#039; =&gt; false,
		&#039;[errors]&#039; =&gt; [[maximum depth reached]],
		&#039;[invalid]&#039; =&gt; [[maximum depth reached]],
		&#039;[repository]&#039; =&gt; &#039;Articles&#039;
	
	},
	&#039;articleid&#039; =&gt; (int) 22816,
	&#039;metaTitle&#039; =&gt; &#039;LATEST NEWS UPDATES | Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney&#039;,
	&#039;metaKeywords&#039; =&gt; &#039;dengue,Health&#039;,
	&#039;metaDesc&#039; =&gt; &#039;
-Down to Earth



Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year


More than 2,916 people have already been reported affected by dengue this year in Delhi....&#039;,
	&#039;disp&#039; =&gt; &#039;&lt;div align=&quot;justify&quot;&gt;-Down to Earth&lt;/div&gt;&lt;p align=&quot;justify&quot;&gt;&lt;br /&gt;&lt;em&gt;Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year&lt;/em&gt;&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.&lt;br /&gt; &lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;&lt;img src=&quot;https://im4change.in/siteadmin/tinymce/uploaded/Dengue.JPG&quot; alt=&quot;Dengue&quot; width=&quot;483&quot; height=&quot;235&quot; /&gt;&lt;br /&gt;Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India&#039;s National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Serotype shifts&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar&#039;s studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Deadly combination&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &amp;quot;We are taking steps to control the vector,&amp;quot; says Dhariwal.&lt;br /&gt; &lt;/p&gt;&#039;,
	&#039;lang&#039; =&gt; &#039;English&#039;,
	&#039;SITE_URL&#039; =&gt; &#039;https://im4change.in/&#039;,
	&#039;site_title&#039; =&gt; &#039;im4change&#039;,
	&#039;adminprix&#039; =&gt; &#039;admin&#039;
]
$article_current = object(App\Model\Entity\Article) {

	&#039;id&#039; =&gt; (int) 22816,
	&#039;title&#039; =&gt; &#039;Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney&#039;,
	&#039;subheading&#039; =&gt; &#039;&#039;,
	&#039;description&#039; =&gt; &#039;&lt;div align=&quot;justify&quot;&gt;
-Down to Earth
&lt;/div&gt;
&lt;p align=&quot;justify&quot;&gt;
&lt;br /&gt;
&lt;em&gt;Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year&lt;/em&gt;
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.&lt;br /&gt;
 
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
&lt;img src=&quot;tinymce/uploaded/Dengue.JPG&quot; alt=&quot;Dengue&quot; width=&quot;483&quot; height=&quot;235&quot; /&gt;&lt;br /&gt;
Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India&#039;s National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Serotype shifts
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar&#039;s studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Deadly combination
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.
&lt;/p&gt;
&lt;p align=&quot;justify&quot;&gt;
Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &amp;quot;We are taking steps to control the vector,&amp;quot; says Dhariwal.&lt;br /&gt;
 
&lt;/p&gt;&#039;,
	&#039;credit_writer&#039; =&gt; &#039;Down to Earth, 8 October, 2013, http://www.downtoearth.org.in/content/dengue-grips-delhi-virus-strain-circulating-year-more-deadly&#039;,
	&#039;article_img&#039; =&gt; &#039;&#039;,
	&#039;article_img_thumb&#039; =&gt; &#039;&#039;,
	&#039;status&#039; =&gt; (int) 1,
	&#039;show_on_home&#039; =&gt; (int) 1,
	&#039;lang&#039; =&gt; &#039;EN&#039;,
	&#039;category_id&#039; =&gt; (int) 16,
	&#039;tag_keyword&#039; =&gt; &#039;&#039;,
	&#039;seo_url&#039; =&gt; &#039;dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970&#039;,
	&#039;meta_title&#039; =&gt; null,
	&#039;meta_keywords&#039; =&gt; null,
	&#039;meta_description&#039; =&gt; null,
	&#039;noindex&#039; =&gt; (int) 0,
	&#039;publish_date&#039; =&gt; object(Cake\I18n\FrozenDate) {},
	&#039;most_visit_section_id&#039; =&gt; null,
	&#039;article_big_img&#039; =&gt; null,
	&#039;liveid&#039; =&gt; (int) 22970,
	&#039;created&#039; =&gt; object(Cake\I18n\FrozenTime) {},
	&#039;modified&#039; =&gt; object(Cake\I18n\FrozenTime) {},
	&#039;edate&#039; =&gt; &#039;&#039;,
	&#039;tags&#039; =&gt; [
		(int) 0 =&gt; object(Cake\ORM\Entity) {},
		(int) 1 =&gt; object(Cake\ORM\Entity) {}
	],
	&#039;category&#039; =&gt; object(App\Model\Entity\Category) {},
	&#039;[new]&#039; =&gt; false,
	&#039;[accessible]&#039; =&gt; [
		&#039;*&#039; =&gt; true,
		&#039;id&#039; =&gt; false
	],
	&#039;[dirty]&#039; =&gt; [],
	&#039;[original]&#039; =&gt; [],
	&#039;[virtual]&#039; =&gt; [],
	&#039;[hasErrors]&#039; =&gt; false,
	&#039;[errors]&#039; =&gt; [],
	&#039;[invalid]&#039; =&gt; [],
	&#039;[repository]&#039; =&gt; &#039;Articles&#039;

}
$articleid = (int) 22816
$metaTitle = &#039;LATEST NEWS UPDATES | Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney&#039;
$metaKeywords = &#039;dengue,Health&#039;
$metaDesc = &#039;
-Down to Earth



Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year


More than 2,916 people have already been reported affected by dengue this year in Delhi....&#039;
$disp = &#039;&lt;div align=&quot;justify&quot;&gt;-Down to Earth&lt;/div&gt;&lt;p align=&quot;justify&quot;&gt;&lt;br /&gt;&lt;em&gt;Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year&lt;/em&gt;&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.&lt;br /&gt; &lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;&lt;img src=&quot;https://im4change.in/siteadmin/tinymce/uploaded/Dengue.JPG&quot; alt=&quot;Dengue&quot; width=&quot;483&quot; height=&quot;235&quot; /&gt;&lt;br /&gt;Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India&#039;s National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Serotype shifts&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar&#039;s studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Deadly combination&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.&lt;/p&gt;&lt;p align=&quot;justify&quot;&gt;Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &amp;quot;We are taking steps to control the vector,&amp;quot; says Dhariwal.&lt;br /&gt; &lt;/p&gt;&#039;
$lang = &#039;English&#039;
$SITE_URL = &#039;https://im4change.in/&#039;
$site_title = &#039;im4change&#039;
$adminprix = &#039;admin&#039;</pre><pre class="stack-trace">include - APP/Template/Layout/printlayout.ctp, line 8
Cake\View\View::_evaluate() - CORE/src/View/View.php, line 1413
Cake\View\View::_render() - CORE/src/View/View.php, line 1374
Cake\View\View::renderLayout() - CORE/src/View/View.php, line 927
Cake\View\View::render() - CORE/src/View/View.php, line 885
Cake\Controller\Controller::render() - CORE/src/Controller/Controller.php, line 791
Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 126
Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94
Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51</pre></div></pre>latest-news-updates/dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970.html"/>
    <meta http-equiv="Content-Type" content="text/html; charset=utf-8"/>
    <link href="https://im4change.in/css/control.css" rel="stylesheet" type="text/css"
          media="all"/>
    <title>LATEST NEWS UPDATES | Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney | Im4change.org</title>
    <meta name="description" content="
-Down to Earth



Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year


More than 2,916 people have already been reported affected by dengue this year in Delhi...."/>
    <script src="https://im4change.in/js/jquery-1.10.2.js"></script>
    <script type="text/javascript" src="https://im4change.in/js/jquery-migrate.min.js"></script>
    <script language="javascript" type="text/javascript">

        $(document).ready(function () {
            var img = $("img")[0]; // Get my img elem
            var pic_real_width, pic_real_height;
            $("<img/>") // Make in memory copy of image to avoid css issues
                .attr("src", $(img).attr("src"))
                .load(function () {
                    pic_real_width = this.width;   // Note: $(this).width() will not
                    pic_real_height = this.height; // work for in memory images.
                });
        });
    </script>
    <style type="text/css">
        @media screen {
            div.divFooter {
                display: block;
            }
        }

        @media print {
            .printbutton {
                display: none !important;
            }
        }
    </style>
</head>
<body>
<table cellpadding="0" cellspacing="0" border="0" width="98%" align="center">
    <tr>
        <td class="top_bg">
            <div class="divFooter">
                <img src="https://im4change.in/images/logo1.jpg" height="59" border="0"
                     alt="Resource centre on India's rural distress" style="padding-top:14px;"/>
            </div>

        </td>
    </tr>
    <tr>
        <td id="topspace">&nbsp;</td>
    </tr>

    <tr id="topspace">
        <td>&nbsp;</td>
    </tr>
    <tr>
        <td height="50" style="border-bottom:1px solid #000; padding-top:10px;" class="printbutton">
            <form><input type="button" value=" Print this page "
                         onclick="window.print();return false;"/></form>
        </td>
    </tr>

    <tr>
        <td width="100%">
            <h1 class="news_headlines" style="font-style:normal">
                <strong>Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney</strong></h1>
        </td>
    </tr>
    <tr>
        <td width="100%" style="font-family:Arial, 'Segoe Script', 'Segoe UI', sans-serif, serif"><font size="3">
                <div align="justify">-Down to Earth</div><p align="justify"><br /><em>Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year</em></p><p align="justify">More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.<br /> </p><p align="justify"><img src="https://im4change.in/siteadmin/tinymce/uploaded/Dengue.JPG" alt="Dengue" width="483" height="235" /><br />Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India's National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.</p><p align="justify">But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.</p><p align="justify">Serotype shifts</p><p align="justify">During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.</p><p align="justify">DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.</p><p align="justify">Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar's studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.</p><p align="justify">Deadly combination</p><p align="justify">Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.</p><p align="justify">These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.</p><p align="justify">Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.</p><p align="justify">Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &quot;We are taking steps to control the vector,&quot; says Dhariwal.<br /> </p>               </font>
        </td>
    </tr>
    <tr>
        <td>&nbsp;</td>
    </tr>

    <tr>
        <td height="50" style="border-top:1px solid #000; border-bottom:1px solid #000;padding-top:10px;">
            <form><input type="button" value=" Print this page "
                         onclick="window.print();return false;"/></form>
        </td>
    </tr>
</table></body>
</html>'

}
$cookies = []
$values = [
	(int) 0 => 'text/html; charset=UTF-8'
]
$name = 'Content-Type'
$first = true
$value = 'text/html; charset=UTF-8'
header - [internal], line ??
Cake\Http\ResponseEmitter::emitHeaders() - CORE/src/Http/ResponseEmitter.php, line 181
Cake\Http\ResponseEmitter::emit() - CORE/src/Http/ResponseEmitter.php, line 55
Cake\Http\Server::emit() - CORE/src/Http/Server.php, line 141
[main] - ROOT/webroot/index.php, line 39

<head>

    <link rel="canonical" href="<?php echo Configure::read('SITE_URL'); ?><?php echo $urlPrefix;?><?php echo $article_current->category->slug; ?>/<?php echo $article_current->seo_url; ?>.html"/>

    <meta http-equiv="Content-Type" content="text/html; charset=utf-8"/>

$viewFile = '/home/brlfuser/public_html/src/Template/Layout/printlayout.ctp'
$dataForView = [
	'article_current' => object(App\Model\Entity\Article) {

		'id' => (int) 22816,
		'title' => 'Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney',
		'subheading' => '',
		'description' => '<div align="justify">
-Down to Earth
</div>
<p align="justify">
<br />
<em>Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year</em>
</p>
<p align="justify">
More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.<br />
 
</p>
<p align="justify">
<img src="tinymce/uploaded/Dengue.JPG" alt="Dengue" width="483" height="235" /><br />
Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India's National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.
</p>
<p align="justify">
But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.
</p>
<p align="justify">
Serotype shifts
</p>
<p align="justify">
During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.
</p>
<p align="justify">
DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.
</p>
<p align="justify">
Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar's studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.
</p>
<p align="justify">
Deadly combination
</p>
<p align="justify">
Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.
</p>
<p align="justify">
These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.
</p>
<p align="justify">
Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.
</p>
<p align="justify">
Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &quot;We are taking steps to control the vector,&quot; says Dhariwal.<br />
 
</p>',
		'credit_writer' => 'Down to Earth, 8 October, 2013, http://www.downtoearth.org.in/content/dengue-grips-delhi-virus-strain-circulating-year-more-deadly',
		'article_img' => '',
		'article_img_thumb' => '',
		'status' => (int) 1,
		'show_on_home' => (int) 1,
		'lang' => 'EN',
		'category_id' => (int) 16,
		'tag_keyword' => '',
		'seo_url' => 'dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970',
		'meta_title' => null,
		'meta_keywords' => null,
		'meta_description' => null,
		'noindex' => (int) 0,
		'publish_date' => object(Cake\I18n\FrozenDate) {},
		'most_visit_section_id' => null,
		'article_big_img' => null,
		'liveid' => (int) 22970,
		'created' => object(Cake\I18n\FrozenTime) {},
		'modified' => object(Cake\I18n\FrozenTime) {},
		'edate' => '',
		'tags' => [
			[maximum depth reached]
		],
		'category' => object(App\Model\Entity\Category) {},
		'[new]' => false,
		'[accessible]' => [
			[maximum depth reached]
		],
		'[dirty]' => [[maximum depth reached]],
		'[original]' => [[maximum depth reached]],
		'[virtual]' => [[maximum depth reached]],
		'[hasErrors]' => false,
		'[errors]' => [[maximum depth reached]],
		'[invalid]' => [[maximum depth reached]],
		'[repository]' => 'Articles'
	
	},
	'articleid' => (int) 22816,
	'metaTitle' => 'LATEST NEWS UPDATES | Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney',
	'metaKeywords' => 'dengue,Health',
	'metaDesc' => '
-Down to Earth



Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year


More than 2,916 people have already been reported affected by dengue this year in Delhi....',
	'disp' => '<div align="justify">-Down to Earth</div><p align="justify"><br /><em>Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year</em></p><p align="justify">More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.<br /> </p><p align="justify"><img src="https://im4change.in/siteadmin/tinymce/uploaded/Dengue.JPG" alt="Dengue" width="483" height="235" /><br />Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India's National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.</p><p align="justify">But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.</p><p align="justify">Serotype shifts</p><p align="justify">During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.</p><p align="justify">DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.</p><p align="justify">Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar's studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.</p><p align="justify">Deadly combination</p><p align="justify">Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.</p><p align="justify">These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.</p><p align="justify">Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.</p><p align="justify">Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &quot;We are taking steps to control the vector,&quot; says Dhariwal.<br /> </p>',
	'lang' => 'English',
	'SITE_URL' => 'https://im4change.in/',
	'site_title' => 'im4change',
	'adminprix' => 'admin'
]
$article_current = object(App\Model\Entity\Article) {

	'id' => (int) 22816,
	'title' => 'Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney',
	'subheading' => '',
	'description' => '<div align="justify">
-Down to Earth
</div>
<p align="justify">
<br />
<em>Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year</em>
</p>
<p align="justify">
More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.<br />
 
</p>
<p align="justify">
<img src="tinymce/uploaded/Dengue.JPG" alt="Dengue" width="483" height="235" /><br />
Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India's National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.
</p>
<p align="justify">
But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.
</p>
<p align="justify">
Serotype shifts
</p>
<p align="justify">
During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.
</p>
<p align="justify">
DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.
</p>
<p align="justify">
Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar's studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.
</p>
<p align="justify">
Deadly combination
</p>
<p align="justify">
Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.
</p>
<p align="justify">
These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.
</p>
<p align="justify">
Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.
</p>
<p align="justify">
Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &quot;We are taking steps to control the vector,&quot; says Dhariwal.<br />
 
</p>',
	'credit_writer' => 'Down to Earth, 8 October, 2013, http://www.downtoearth.org.in/content/dengue-grips-delhi-virus-strain-circulating-year-more-deadly',
	'article_img' => '',
	'article_img_thumb' => '',
	'status' => (int) 1,
	'show_on_home' => (int) 1,
	'lang' => 'EN',
	'category_id' => (int) 16,
	'tag_keyword' => '',
	'seo_url' => 'dengue-grips-delhi-virus-strain-circulating-this-year-more-deadly-vibha-varshney-22970',
	'meta_title' => null,
	'meta_keywords' => null,
	'meta_description' => null,
	'noindex' => (int) 0,
	'publish_date' => object(Cake\I18n\FrozenDate) {},
	'most_visit_section_id' => null,
	'article_big_img' => null,
	'liveid' => (int) 22970,
	'created' => object(Cake\I18n\FrozenTime) {},
	'modified' => object(Cake\I18n\FrozenTime) {},
	'edate' => '',
	'tags' => [
		(int) 0 => object(Cake\ORM\Entity) {},
		(int) 1 => object(Cake\ORM\Entity) {}
	],
	'category' => object(App\Model\Entity\Category) {},
	'[new]' => false,
	'[accessible]' => [
		'*' => true,
		'id' => false
	],
	'[dirty]' => [],
	'[original]' => [],
	'[virtual]' => [],
	'[hasErrors]' => false,
	'[errors]' => [],
	'[invalid]' => [],
	'[repository]' => 'Articles'

}
$articleid = (int) 22816
$metaTitle = 'LATEST NEWS UPDATES | Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney'
$metaKeywords = 'dengue,Health'
$metaDesc = '
-Down to Earth



Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year


More than 2,916 people have already been reported affected by dengue this year in Delhi....'
$disp = '<div align="justify">-Down to Earth</div><p align="justify"><br /><em>Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year</em></p><p align="justify">More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported.<br /> </p><p align="justify"><img src="https://im4change.in/siteadmin/tinymce/uploaded/Dengue.JPG" alt="Dengue" width="483" height="235" /><br />Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India's National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases.</p><p align="justify">But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant.</p><p align="justify">Serotype shifts</p><p align="justify">During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11.</p><p align="justify">DENV2 is more serious as it leads to more mortality, says Easwaran  Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality.</p><p align="justify">Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar's studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology.</p><p align="justify">Deadly combination</p><p align="justify">Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future.</p><p align="justify">These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says.</p><p align="justify">Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present.</p><p align="justify">Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. &quot;We are taking steps to control the vector,&quot; says Dhariwal.<br /> </p>'
$lang = 'English'
$SITE_URL = 'https://im4change.in/'
$site_title = 'im4change'
$adminprix = 'admin'

include - APP/Template/Layout/printlayout.ctp, line 8
Cake\View\View::_evaluate() - CORE/src/View/View.php, line 1413
Cake\View\View::_render() - CORE/src/View/View.php, line 1374
Cake\View\View::renderLayout() - CORE/src/View/View.php, line 927
Cake\View\View::render() - CORE/src/View/View.php, line 885
Cake\Controller\Controller::render() - CORE/src/Controller/Controller.php, line 791
Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 126
Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94
Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51

Dengue grips Delhi: virus strain circulating this year more deadly -Vibha Varshney

-Down to Earth Serotype DENV 2 has returned after a gap of a few years, which could be a reason for higher number of cases this year More than 2,916 people have already been reported affected by dengue this year in Delhi. This has been the highest since 2010 when more than 3,782 cases were reported. Small puddles of water created by intermittent rains are the main reason behind this surge as this provides places for the mosquito vector Aedes aegypti to breed, says A C Dhariwal, director of India's National Vector Borne Disease Control Programme, the nodal agency in the country for prevention and control of vector borne diseases. But the bigger contributor to the increase in the number of cases has been the fact that mosquitoes are transmitting serotype DENV-2 this year. Till last year, the circulating virus was of serotype DENV-1, he reveals. There are four serotypes of dengue virus and while infection with one protects the person from being re-infected by this serotype, it does not protect from the remaining ones. The four serotypes are classified separately as each has different interactions with the antibodies in human blood serum. at present all serotypes circulate together in the environment and any one of them could become dominant. Serotype shifts During the past decade, such shifts in the serotype have been seen periodically in the capital. Overall, DENV-2 and DENV-3 were the predominant serotypes during 2003-2007, but DENV-1 replaced these strains in 2008, reported researchers from Department of Microbiology, Maulana Azad Medical College, New Delhi in the Indian Journal of Medical Microbiology. Another study published in Journal of Vector Borne Diseases says DENV-1 was circulating in Delhi in 2010-11. DENV2 is more serious as it leads to more mortality, says Easwaran Sreekumar, scientist at the Rajiv Gandhi Centre for Biotechnology, Kerala. He studies dengue epidemics in Kerala where this serotype is leading to severe symptoms like shock syndrome and haemorrhages, leading to high mortality. Another contributor to the high incidence of the disease could be that the serotypes themselves are showing some minor changes in the genetic make-up. For example, lineages have been observed in serotype 3 in Kerala. Sreekumar's studies show the presence of lineage IV strains of serotype 3. Before this, lineage III strains were predominant in the area. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world, say researchers in Virology Journal. Similar shifts have been seen in Lucknow, too, where researchers reported an active circulation of a new lineage of DENV-3 in March issue of Iran Journal of Microbiology. Deadly combination Though recent reports of circulation of new lineages in Delhi are not published, earlier studies show presence of two independent lineages of DENV-1 in Delhi during 2005 and 2006. Researchers in the study published in the International Journal of Infectious Diseases in September 2008 say that the introduction of an independent lineage of DENV-1 and its co-circulation with DENV-3 in Delhi could result in a more severe outbreak in the near future. These lineages can be formed due to genetic changes or could be imported from outside. For example, lineage IV found in Kerala has been found predominantly in Singapore earlier. Sreekumar says that it is difficult to ascertain whether the strain originated in India and then was exported outside or whether, it originated in Singapore and was imported. The answers can come only through long-term studies on the virus, he says. Studies on the virus are difficult as patients come in late and the virus is no longer circulating in the blood. The virus is present in the blood only during the first few days when fever is the predominant symptom. Patients come to doctors only after this when complications set in but at that time, the virus is no longer present. Clinical management of the symptoms such as emphasis on oral rehydaration is important, says Sreekumar. Preventing breeding spaces and reducing mosquito bites is the key to tackling the menace, says Atul Gogia, consultant with the internal medicine department of Sir Ganga Ram Hospital, Delhi. "We are taking steps to control the vector," says Dhariwal.