Deprecated (16384): The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 73 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php. [CORE/src/Core/functions.php, line 311]Code Context
trigger_error($message, E_USER_DEPRECATED);
}
$message = 'The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 73 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php.' $stackFrame = (int) 1 $trace = [ (int) 0 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ServerRequest.php', 'line' => (int) 2421, 'function' => 'deprecationWarning', 'args' => [ (int) 0 => 'The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead.' ] ], (int) 1 => [ 'file' => '/home/brlfuser/public_html/src/Controller/ArtileDetailController.php', 'line' => (int) 73, 'function' => 'offsetGet', 'class' => 'Cake\Http\ServerRequest', 'object' => object(Cake\Http\ServerRequest) {}, 'type' => '->', 'args' => [ (int) 0 => 'catslug' ] ], (int) 2 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Controller/Controller.php', 'line' => (int) 610, 'function' => 'printArticle', 'class' => 'App\Controller\ArtileDetailController', 'object' => object(App\Controller\ArtileDetailController) {}, 'type' => '->', 'args' => [] ], (int) 3 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ActionDispatcher.php', 'line' => (int) 120, 'function' => 'invokeAction', 'class' => 'Cake\Controller\Controller', 'object' => object(App\Controller\ArtileDetailController) {}, 'type' => '->', 'args' => [] ], (int) 4 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ActionDispatcher.php', 'line' => (int) 94, 'function' => '_invoke', 'class' => 'Cake\Http\ActionDispatcher', 'object' => object(Cake\Http\ActionDispatcher) {}, 'type' => '->', 'args' => [ (int) 0 => object(App\Controller\ArtileDetailController) {} ] ], (int) 5 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/BaseApplication.php', 'line' => (int) 235, 'function' => 'dispatch', 'class' => 'Cake\Http\ActionDispatcher', 'object' => object(Cake\Http\ActionDispatcher) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 6 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Http\BaseApplication', 'object' => object(App\Application) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 7 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Routing/Middleware/RoutingMiddleware.php', 'line' => (int) 162, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 8 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Routing\Middleware\RoutingMiddleware', 'object' => object(Cake\Routing\Middleware\RoutingMiddleware) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 9 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Routing/Middleware/AssetMiddleware.php', 'line' => (int) 88, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 10 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Routing\Middleware\AssetMiddleware', 'object' => object(Cake\Routing\Middleware\AssetMiddleware) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 11 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Middleware/ErrorHandlerMiddleware.php', 'line' => (int) 96, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 12 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Error\Middleware\ErrorHandlerMiddleware', 'object' => object(Cake\Error\Middleware\ErrorHandlerMiddleware) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 13 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 51, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 14 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Server.php', 'line' => (int) 98, 'function' => 'run', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\MiddlewareQueue) {}, (int) 1 => object(Cake\Http\ServerRequest) {}, (int) 2 => object(Cake\Http\Response) {} ] ], (int) 15 => [ 'file' => '/home/brlfuser/public_html/webroot/index.php', 'line' => (int) 39, 'function' => 'run', 'class' => 'Cake\Http\Server', 'object' => object(Cake\Http\Server) {}, 'type' => '->', 'args' => [] ] ] $frame = [ 'file' => '/home/brlfuser/public_html/src/Controller/ArtileDetailController.php', 'line' => (int) 73, 'function' => 'offsetGet', 'class' => 'Cake\Http\ServerRequest', 'object' => object(Cake\Http\ServerRequest) { trustProxy => false [protected] params => [ [maximum depth reached] ] [protected] data => [[maximum depth reached]] [protected] query => [[maximum depth reached]] [protected] cookies => [ [maximum depth reached] ] [protected] _environment => [ [maximum depth reached] ] [protected] url => 'latest-news-updates/fillip-to-cheaper-hepatitis-c-drug-gs-mudur-4675073/print' [protected] base => '' [protected] webroot => '/' [protected] here => '/latest-news-updates/fillip-to-cheaper-hepatitis-c-drug-gs-mudur-4675073/print' [protected] trustedProxies => [[maximum depth reached]] [protected] _input => null [protected] _detectors => [ [maximum depth reached] ] [protected] _detectorCache => [ [maximum depth reached] ] [protected] stream => object(Zend\Diactoros\PhpInputStream) {} [protected] uri => object(Zend\Diactoros\Uri) {} [protected] session => object(Cake\Http\Session) {} [protected] attributes => [[maximum depth reached]] [protected] emulatedAttributes => [ [maximum depth reached] ] [protected] uploadedFiles => [[maximum depth reached]] [protected] protocol => null [protected] requestTarget => null [private] deprecatedProperties => [ [maximum depth reached] ] }, 'type' => '->', 'args' => [ (int) 0 => 'catslug' ] ]deprecationWarning - CORE/src/Core/functions.php, line 311 Cake\Http\ServerRequest::offsetGet() - CORE/src/Http/ServerRequest.php, line 2421 App\Controller\ArtileDetailController::printArticle() - APP/Controller/ArtileDetailController.php, line 73 Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 610 Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 120 Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94 Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51 Cake\Http\Server::run() - CORE/src/Http/Server.php, line 98
Deprecated (16384): The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 74 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php. [CORE/src/Core/functions.php, line 311]Code Context
trigger_error($message, E_USER_DEPRECATED);
}
$message = 'The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 74 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php.' $stackFrame = (int) 1 $trace = [ (int) 0 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ServerRequest.php', 'line' => (int) 2421, 'function' => 'deprecationWarning', 'args' => [ (int) 0 => 'The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead.' ] ], (int) 1 => [ 'file' => '/home/brlfuser/public_html/src/Controller/ArtileDetailController.php', 'line' => (int) 74, 'function' => 'offsetGet', 'class' => 'Cake\Http\ServerRequest', 'object' => object(Cake\Http\ServerRequest) {}, 'type' => '->', 'args' => [ (int) 0 => 'artileslug' ] ], (int) 2 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Controller/Controller.php', 'line' => (int) 610, 'function' => 'printArticle', 'class' => 'App\Controller\ArtileDetailController', 'object' => object(App\Controller\ArtileDetailController) {}, 'type' => '->', 'args' => [] ], (int) 3 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ActionDispatcher.php', 'line' => (int) 120, 'function' => 'invokeAction', 'class' => 'Cake\Controller\Controller', 'object' => object(App\Controller\ArtileDetailController) {}, 'type' => '->', 'args' => [] ], (int) 4 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ActionDispatcher.php', 'line' => (int) 94, 'function' => '_invoke', 'class' => 'Cake\Http\ActionDispatcher', 'object' => object(Cake\Http\ActionDispatcher) {}, 'type' => '->', 'args' => [ (int) 0 => object(App\Controller\ArtileDetailController) {} ] ], (int) 5 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/BaseApplication.php', 'line' => (int) 235, 'function' => 'dispatch', 'class' => 'Cake\Http\ActionDispatcher', 'object' => object(Cake\Http\ActionDispatcher) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 6 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Http\BaseApplication', 'object' => object(App\Application) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 7 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Routing/Middleware/RoutingMiddleware.php', 'line' => (int) 162, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 8 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Routing\Middleware\RoutingMiddleware', 'object' => object(Cake\Routing\Middleware\RoutingMiddleware) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 9 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Routing/Middleware/AssetMiddleware.php', 'line' => (int) 88, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 10 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Routing\Middleware\AssetMiddleware', 'object' => object(Cake\Routing\Middleware\AssetMiddleware) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 11 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Middleware/ErrorHandlerMiddleware.php', 'line' => (int) 96, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 12 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Error\Middleware\ErrorHandlerMiddleware', 'object' => object(Cake\Error\Middleware\ErrorHandlerMiddleware) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 13 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 51, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 14 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Server.php', 'line' => (int) 98, 'function' => 'run', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\MiddlewareQueue) {}, (int) 1 => object(Cake\Http\ServerRequest) {}, (int) 2 => object(Cake\Http\Response) {} ] ], (int) 15 => [ 'file' => '/home/brlfuser/public_html/webroot/index.php', 'line' => (int) 39, 'function' => 'run', 'class' => 'Cake\Http\Server', 'object' => object(Cake\Http\Server) {}, 'type' => '->', 'args' => [] ] ] $frame = [ 'file' => '/home/brlfuser/public_html/src/Controller/ArtileDetailController.php', 'line' => (int) 74, 'function' => 'offsetGet', 'class' => 'Cake\Http\ServerRequest', 'object' => object(Cake\Http\ServerRequest) { trustProxy => false [protected] params => [ [maximum depth reached] ] [protected] data => [[maximum depth reached]] [protected] query => [[maximum depth reached]] [protected] cookies => [ [maximum depth reached] ] [protected] _environment => [ [maximum depth reached] ] [protected] url => 'latest-news-updates/fillip-to-cheaper-hepatitis-c-drug-gs-mudur-4675073/print' [protected] base => '' [protected] webroot => '/' [protected] here => '/latest-news-updates/fillip-to-cheaper-hepatitis-c-drug-gs-mudur-4675073/print' [protected] trustedProxies => [[maximum depth reached]] [protected] _input => null [protected] _detectors => [ [maximum depth reached] ] [protected] _detectorCache => [ [maximum depth reached] ] [protected] stream => object(Zend\Diactoros\PhpInputStream) {} [protected] uri => object(Zend\Diactoros\Uri) {} [protected] session => object(Cake\Http\Session) {} [protected] attributes => [[maximum depth reached]] [protected] emulatedAttributes => [ [maximum depth reached] ] [protected] uploadedFiles => [[maximum depth reached]] [protected] protocol => null [protected] requestTarget => null [private] deprecatedProperties => [ [maximum depth reached] ] }, 'type' => '->', 'args' => [ (int) 0 => 'artileslug' ] ]deprecationWarning - CORE/src/Core/functions.php, line 311 Cake\Http\ServerRequest::offsetGet() - CORE/src/Http/ServerRequest.php, line 2421 App\Controller\ArtileDetailController::printArticle() - APP/Controller/ArtileDetailController.php, line 74 Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 610 Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 120 Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94 Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51 Cake\Http\Server::run() - CORE/src/Http/Server.php, line 98
Warning (512): Unable to emit headers. Headers sent in file=/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php line=853 [CORE/src/Http/ResponseEmitter.php, line 48]Code Contextif (Configure::read('debug')) {
trigger_error($message, E_USER_WARNING);
} else {
$response = object(Cake\Http\Response) { 'status' => (int) 200, 'contentType' => 'text/html', 'headers' => [ 'Content-Type' => [ [maximum depth reached] ] ], 'file' => null, 'fileRange' => [], 'cookies' => object(Cake\Http\Cookie\CookieCollection) {}, 'cacheDirectives' => [], 'body' => '<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd"> <html xmlns="http://www.w3.org/1999/xhtml"> <head> <link rel="canonical" href="https://im4change.in/<pre class="cake-error"><a href="javascript:void(0);" onclick="document.getElementById('cakeErr68030c5f75e61-trace').style.display = (document.getElementById('cakeErr68030c5f75e61-trace').style.display == 'none' ? '' : 'none');"><b>Notice</b> (8)</a>: Undefined variable: urlPrefix [<b>APP/Template/Layout/printlayout.ctp</b>, line <b>8</b>]<div id="cakeErr68030c5f75e61-trace" class="cake-stack-trace" style="display: none;"><a href="javascript:void(0);" onclick="document.getElementById('cakeErr68030c5f75e61-code').style.display = (document.getElementById('cakeErr68030c5f75e61-code').style.display == 'none' ? '' : 'none')">Code</a> <a href="javascript:void(0);" onclick="document.getElementById('cakeErr68030c5f75e61-context').style.display = (document.getElementById('cakeErr68030c5f75e61-context').style.display == 'none' ? '' : 'none')">Context</a><pre id="cakeErr68030c5f75e61-code" class="cake-code-dump" style="display: none;"><code><span style="color: #000000"><span style="color: #0000BB"></span><span style="color: #007700"><</span><span style="color: #0000BB">head</span><span style="color: #007700">> </span></span></code> <span class="code-highlight"><code><span style="color: #000000"> <link rel="canonical" href="<span style="color: #0000BB"><?php </span><span style="color: #007700">echo </span><span style="color: #0000BB">Configure</span><span style="color: #007700">::</span><span style="color: #0000BB">read</span><span style="color: #007700">(</span><span style="color: #DD0000">'SITE_URL'</span><span style="color: #007700">); </span><span style="color: #0000BB">?><?php </span><span style="color: #007700">echo </span><span style="color: #0000BB">$urlPrefix</span><span style="color: #007700">;</span><span style="color: #0000BB">?><?php </span><span style="color: #007700">echo </span><span style="color: #0000BB">$article_current</span><span style="color: #007700">-></span><span style="color: #0000BB">category</span><span style="color: #007700">-></span><span style="color: #0000BB">slug</span><span style="color: #007700">; </span><span style="color: #0000BB">?></span>/<span style="color: #0000BB"><?php </span><span style="color: #007700">echo </span><span style="color: #0000BB">$article_current</span><span style="color: #007700">-></span><span style="color: #0000BB">seo_url</span><span style="color: #007700">; </span><span style="color: #0000BB">?></span>.html"/> </span></code></span> <code><span style="color: #000000"><span style="color: #0000BB"> </span><span style="color: #007700"><</span><span style="color: #0000BB">meta http</span><span style="color: #007700">-</span><span style="color: #0000BB">equiv</span><span style="color: #007700">=</span><span style="color: #DD0000">"Content-Type" </span><span style="color: #0000BB">content</span><span style="color: #007700">=</span><span style="color: #DD0000">"text/html; charset=utf-8"</span><span style="color: #007700">/> </span></span></code></pre><pre id="cakeErr68030c5f75e61-context" class="cake-context" style="display: none;">$viewFile = '/home/brlfuser/public_html/src/Template/Layout/printlayout.ctp' $dataForView = [ 'article_current' => object(App\Model\Entity\Article) { 'id' => (int) 27028, 'title' => 'Fillip to cheaper hepatitis C drug -GS Mudur', 'subheading' => '', 'description' => '<div align="justify"> -The Telegraph </div> <p align="justify"> <em>New Delhi: </em>India's patent regulating agency today rejected a US company's patent claim on a drug to treat hepatitis C, raising hopes that generic drug makers could now produce cheaper versions of the medicine. </p> <p align="justify"> The Indian Patents Controller has denied a patent to sofosbuvir from Gilead, a US biopharmaceutical company that had last year pledged to make the oral drug available in India and 90 other developing countries at $900 (Rs 55,600) for a 12-week course of treatment. </p> <p align="justify"> The decision will allow generic drug makers to manufacture their own low-cost versions of the medicine. A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment. </p> <p align="justify"> &quot;This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price,&quot; said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs. </p> <p align="justify"> Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900. </p> <p align="justify"> It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. But patients' rights groups believe the drug would remain out of reach of most Indian patients even at those lowered prices. </p> <p align="justify"> The MSF Access Campaign plans to expand treatment for hepatitis C in India and eight other developing countries. It has been hoping for inexpensive versions of the medicine that it expects will remain the &quot;backbone of (the) hepatitis C treatment regimen in the coming years&quot;. </p> <p align="justify"> Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin. </p> <p align="justify"> But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir. </p> <p align="justify"> &quot;We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment,&quot; said Andrew Hill, a senior research fellow at Liverpool University in the UK. </p> <p align="justify"> Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several &quot;direct-acting&quot; anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course. </p> <p align="justify"> The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. Many health activists regard this clause as a safeguard. </p> <p align="justify"> Gilead has the right to move an appeal with the patent authority or approach an Indian court. </p>', 'credit_writer' => 'The Telegraph, 16 January, 2015, http://www.telegraphindia.com/1150116/jsp/nation/story_8708.jsp#.VLiwoHvxyBE', 'article_img' => '', 'article_img_thumb' => '', 'status' => (int) 1, 'show_on_home' => (int) 1, 'lang' => 'EN', 'category_id' => (int) 16, 'tag_keyword' => '', 'seo_url' => 'fillip-to-cheaper-hepatitis-c-drug-gs-mudur-4675073', 'meta_title' => null, 'meta_keywords' => null, 'meta_description' => null, 'noindex' => (int) 0, 'publish_date' => object(Cake\I18n\FrozenDate) {}, 'most_visit_section_id' => null, 'article_big_img' => null, 'liveid' => (int) 4675073, 'created' => object(Cake\I18n\FrozenTime) {}, 'modified' => object(Cake\I18n\FrozenTime) {}, 'edate' => '', 'tags' => [ [maximum depth reached] ], 'category' => object(App\Model\Entity\Category) {}, '[new]' => false, '[accessible]' => [ [maximum depth reached] ], '[dirty]' => [[maximum depth reached]], '[original]' => [[maximum depth reached]], '[virtual]' => [[maximum depth reached]], '[hasErrors]' => false, '[errors]' => [[maximum depth reached]], '[invalid]' => [[maximum depth reached]], '[repository]' => 'Articles' }, 'articleid' => (int) 27028, 'metaTitle' => 'LATEST NEWS UPDATES | Fillip to cheaper hepatitis C drug -GS Mudur', 'metaKeywords' => 'Intellectual Property Rights,IPRs,patent,patents,generic medicine,generic medicines,Hepatitis C', 'metaDesc' => ' -The Telegraph New Delhi: India's patent regulating agency today rejected a US company's patent claim on a drug to treat hepatitis C, raising hopes that generic drug makers could now produce cheaper versions of the medicine. 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A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment.</p><p align="justify">&quot;This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price,&quot; said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs.</p><p align="justify">Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900.</p><p align="justify">It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. But patients' rights groups believe the drug would remain out of reach of most Indian patients even at those lowered prices.</p><p align="justify">The MSF Access Campaign plans to expand treatment for hepatitis C in India and eight other developing countries. It has been hoping for inexpensive versions of the medicine that it expects will remain the &quot;backbone of (the) hepatitis C treatment regimen in the coming years&quot;.</p><p align="justify">Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin.</p><p align="justify">But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir.</p><p align="justify">&quot;We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment,&quot; said Andrew Hill, a senior research fellow at Liverpool University in the UK.</p><p align="justify">Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several &quot;direct-acting&quot; anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course.</p><p align="justify">The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. Many health activists regard this clause as a safeguard.</p><p align="justify">Gilead has the right to move an appeal with the patent authority or approach an Indian court.</p>', 'lang' => 'English', 'SITE_URL' => 'https://im4change.in/', 'site_title' => 'im4change', 'adminprix' => 'admin' ] $article_current = object(App\Model\Entity\Article) { 'id' => (int) 27028, 'title' => 'Fillip to cheaper hepatitis C drug -GS Mudur', 'subheading' => '', 'description' => '<div align="justify"> -The Telegraph </div> <p align="justify"> <em>New Delhi: </em>India's patent regulating agency today rejected a US company's patent claim on a drug to treat hepatitis C, raising hopes that generic drug makers could now produce cheaper versions of the medicine. </p> <p align="justify"> The Indian Patents Controller has denied a patent to sofosbuvir from Gilead, a US biopharmaceutical company that had last year pledged to make the oral drug available in India and 90 other developing countries at $900 (Rs 55,600) for a 12-week course of treatment. </p> <p align="justify"> The decision will allow generic drug makers to manufacture their own low-cost versions of the medicine. A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment. </p> <p align="justify"> &quot;This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price,&quot; said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs. </p> <p align="justify"> Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900. </p> <p align="justify"> It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. But patients' rights groups believe the drug would remain out of reach of most Indian patients even at those lowered prices. </p> <p align="justify"> The MSF Access Campaign plans to expand treatment for hepatitis C in India and eight other developing countries. It has been hoping for inexpensive versions of the medicine that it expects will remain the &quot;backbone of (the) hepatitis C treatment regimen in the coming years&quot;. </p> <p align="justify"> Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin. </p> <p align="justify"> But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir. </p> <p align="justify"> &quot;We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment,&quot; said Andrew Hill, a senior research fellow at Liverpool University in the UK. </p> <p align="justify"> Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several &quot;direct-acting&quot; anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course. </p> <p align="justify"> The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. 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A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment.</p><p align="justify">&quot;This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price,&quot; said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs.</p><p align="justify">Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900.</p><p align="justify">It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. But patients' rights groups believe the drug would remain out of reach of most Indian patients even at those lowered prices.</p><p align="justify">The MSF Access Campaign plans to expand treatment for hepatitis C in India and eight other developing countries. It has been hoping for inexpensive versions of the medicine that it expects will remain the &quot;backbone of (the) hepatitis C treatment regimen in the coming years&quot;.</p><p align="justify">Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin.</p><p align="justify">But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir.</p><p align="justify">&quot;We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment,&quot; said Andrew Hill, a senior research fellow at Liverpool University in the UK.</p><p align="justify">Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several &quot;direct-acting&quot; anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course.</p><p align="justify">The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. Many health activists regard this clause as a safeguard.</p><p align="justify">Gilead has the right to move an appeal with the patent authority or approach an Indian court.</p>' $lang = 'English' $SITE_URL = 'https://im4change.in/' $site_title = 'im4change' $adminprix = 'admin'</pre><pre class="stack-trace">include - APP/Template/Layout/printlayout.ctp, line 8 Cake\View\View::_evaluate() - CORE/src/View/View.php, line 1413 Cake\View\View::_render() - CORE/src/View/View.php, line 1374 Cake\View\View::renderLayout() - CORE/src/View/View.php, line 927 Cake\View\View::render() - CORE/src/View/View.php, line 885 Cake\Controller\Controller::render() - CORE/src/Controller/Controller.php, line 791 Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 126 Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94 Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51</pre></div></pre>latest-news-updates/fillip-to-cheaper-hepatitis-c-drug-gs-mudur-4675073.html"/> <meta http-equiv="Content-Type" content="text/html; charset=utf-8"/> <link href="https://im4change.in/css/control.css" rel="stylesheet" type="text/css" media="all"/> <title>LATEST NEWS UPDATES | Fillip to cheaper hepatitis C drug -GS Mudur | Im4change.org</title> <meta name="description" content=" -The Telegraph New Delhi: India's patent regulating agency today rejected a US company's patent claim on a drug to treat hepatitis C, raising hopes that generic drug makers could now produce cheaper versions of the medicine. The Indian Patents Controller has denied..."/> <script src="https://im4change.in/js/jquery-1.10.2.js"></script> <script type="text/javascript" src="https://im4change.in/js/jquery-migrate.min.js"></script> <script language="javascript" type="text/javascript"> $(document).ready(function () { var img = $("img")[0]; // Get my img elem var pic_real_width, pic_real_height; $("<img/>") // Make in memory copy of image to avoid css issues .attr("src", $(img).attr("src")) .load(function () { pic_real_width = this.width; // Note: $(this).width() will not pic_real_height = this.height; // work for in memory images. }); }); </script> <style type="text/css"> @media screen { div.divFooter { display: block; } } @media print { .printbutton { display: none !important; } } </style> </head> <body> <table cellpadding="0" cellspacing="0" border="0" width="98%" align="center"> <tr> <td class="top_bg"> <div class="divFooter"> <img src="https://im4change.in/images/logo1.jpg" height="59" border="0" alt="Resource centre on India's rural distress" style="padding-top:14px;"/> </div> </td> </tr> <tr> <td id="topspace"> </td> </tr> <tr id="topspace"> <td> </td> </tr> <tr> <td height="50" style="border-bottom:1px solid #000; padding-top:10px;" class="printbutton"> <form><input type="button" value=" Print this page " onclick="window.print();return false;"/></form> </td> </tr> <tr> <td width="100%"> <h1 class="news_headlines" style="font-style:normal"> <strong>Fillip to cheaper hepatitis C drug -GS Mudur</strong></h1> </td> </tr> <tr> <td width="100%" style="font-family:Arial, 'Segoe Script', 'Segoe UI', sans-serif, serif"><font size="3"> <div align="justify">-The Telegraph</div><p align="justify"><em>New Delhi: </em>India's patent regulating agency today rejected a US company's patent claim on a drug to treat hepatitis C, raising hopes that generic drug makers could now produce cheaper versions of the medicine.</p><p align="justify">The Indian Patents Controller has denied a patent to sofosbuvir from Gilead, a US biopharmaceutical company that had last year pledged to make the oral drug available in India and 90 other developing countries at $900 (Rs 55,600) for a 12-week course of treatment.</p><p align="justify">The decision will allow generic drug makers to manufacture their own low-cost versions of the medicine. A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment.</p><p align="justify">"This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price," said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs.</p><p align="justify">Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900.</p><p align="justify">It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. But patients' rights groups believe the drug would remain out of reach of most Indian patients even at those lowered prices.</p><p align="justify">The MSF Access Campaign plans to expand treatment for hepatitis C in India and eight other developing countries. It has been hoping for inexpensive versions of the medicine that it expects will remain the "backbone of (the) hepatitis C treatment regimen in the coming years".</p><p align="justify">Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin.</p><p align="justify">But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir.</p><p align="justify">"We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment," said Andrew Hill, a senior research fellow at Liverpool University in the UK.</p><p align="justify">Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several "direct-acting" anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course.</p><p align="justify">The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. Many health activists regard this clause as a safeguard.</p><p align="justify">Gilead has the right to move an appeal with the patent authority or approach an Indian court.</p> </font> </td> </tr> <tr> <td> </td> </tr> <tr> <td height="50" style="border-top:1px solid #000; border-bottom:1px solid #000;padding-top:10px;"> <form><input type="button" value=" Print this page " onclick="window.print();return false;"/></form> </td> </tr> </table></body> </html>' } $maxBufferLength = (int) 8192 $file = '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php' $line = (int) 853 $message = 'Unable to emit headers. Headers sent in file=/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php line=853'Cake\Http\ResponseEmitter::emit() - CORE/src/Http/ResponseEmitter.php, line 48 Cake\Http\Server::emit() - CORE/src/Http/Server.php, line 141 [main] - ROOT/webroot/index.php, line 39
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The Indian Patents Controller has denied..."/> <script src="https://im4change.in/js/jquery-1.10.2.js"></script> <script type="text/javascript" src="https://im4change.in/js/jquery-migrate.min.js"></script> <script language="javascript" type="text/javascript"> $(document).ready(function () { var img = $("img")[0]; // Get my img elem var pic_real_width, pic_real_height; $("<img/>") // Make in memory copy of image to avoid css issues .attr("src", $(img).attr("src")) .load(function () { pic_real_width = this.width; // Note: $(this).width() will not pic_real_height = this.height; // work for in memory images. }); }); </script> <style type="text/css"> @media screen { div.divFooter { display: block; } } @media print { .printbutton { display: none !important; } } </style> </head> <body> <table cellpadding="0" cellspacing="0" border="0" width="98%" align="center"> <tr> <td class="top_bg"> <div class="divFooter"> <img src="https://im4change.in/images/logo1.jpg" height="59" border="0" alt="Resource centre on India's rural distress" style="padding-top:14px;"/> </div> </td> </tr> <tr> <td id="topspace"> </td> </tr> <tr id="topspace"> <td> </td> </tr> <tr> <td height="50" style="border-bottom:1px solid #000; padding-top:10px;" class="printbutton"> <form><input type="button" value=" Print this page " onclick="window.print();return false;"/></form> </td> </tr> <tr> <td width="100%"> <h1 class="news_headlines" style="font-style:normal"> <strong>Fillip to cheaper hepatitis C drug -GS Mudur</strong></h1> </td> </tr> <tr> <td width="100%" style="font-family:Arial, 'Segoe Script', 'Segoe UI', sans-serif, serif"><font size="3"> <div align="justify">-The Telegraph</div><p align="justify"><em>New Delhi: </em>India's patent regulating agency today rejected a US company's patent claim on a drug to treat hepatitis C, raising hopes that generic drug makers could now produce cheaper versions of the medicine.</p><p align="justify">The Indian Patents Controller has denied a patent to sofosbuvir from Gilead, a US biopharmaceutical company that had last year pledged to make the oral drug available in India and 90 other developing countries at $900 (Rs 55,600) for a 12-week course of treatment.</p><p align="justify">The decision will allow generic drug makers to manufacture their own low-cost versions of the medicine. A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment.</p><p align="justify">"This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price," said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs.</p><p align="justify">Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900.</p><p align="justify">It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. But patients' rights groups believe the drug would remain out of reach of most Indian patients even at those lowered prices.</p><p align="justify">The MSF Access Campaign plans to expand treatment for hepatitis C in India and eight other developing countries. It has been hoping for inexpensive versions of the medicine that it expects will remain the "backbone of (the) hepatitis C treatment regimen in the coming years".</p><p align="justify">Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin.</p><p align="justify">But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir.</p><p align="justify">"We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment," said Andrew Hill, a senior research fellow at Liverpool University in the UK.</p><p align="justify">Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several "direct-acting" anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course.</p><p align="justify">The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. Many health activists regard this clause as a safeguard.</p><p align="justify">Gilead has the right to move an appeal with the patent authority or approach an Indian court.</p> </font> </td> </tr> <tr> <td> </td> </tr> <tr> <td height="50" style="border-top:1px solid #000; border-bottom:1px solid #000;padding-top:10px;"> <form><input type="button" value=" Print this page " onclick="window.print();return false;"/></form> </td> </tr> </table></body> </html>' } $reasonPhrase = 'OK'header - [internal], line ?? Cake\Http\ResponseEmitter::emitStatusLine() - CORE/src/Http/ResponseEmitter.php, line 148 Cake\Http\ResponseEmitter::emit() - CORE/src/Http/ResponseEmitter.php, line 54 Cake\Http\Server::emit() - CORE/src/Http/Server.php, line 141 [main] - ROOT/webroot/index.php, line 39
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'' : 'none')">Context</a><pre id="cakeErr68030c5f75e61-code" class="cake-code-dump" style="display: none;"><code><span style="color: #000000"><span style="color: #0000BB"></span><span style="color: #007700"><</span><span style="color: #0000BB">head</span><span style="color: #007700">> </span></span></code> <span class="code-highlight"><code><span style="color: #000000"> <link rel="canonical" href="<span style="color: #0000BB"><?php </span><span style="color: #007700">echo </span><span style="color: #0000BB">Configure</span><span style="color: #007700">::</span><span style="color: #0000BB">read</span><span style="color: #007700">(</span><span style="color: #DD0000">'SITE_URL'</span><span style="color: #007700">); </span><span style="color: #0000BB">?><?php </span><span style="color: #007700">echo </span><span style="color: #0000BB">$urlPrefix</span><span style="color: #007700">;</span><span style="color: #0000BB">?><?php </span><span style="color: #007700">echo </span><span style="color: #0000BB">$article_current</span><span style="color: #007700">-></span><span style="color: #0000BB">category</span><span style="color: #007700">-></span><span style="color: #0000BB">slug</span><span style="color: #007700">; </span><span style="color: #0000BB">?></span>/<span style="color: #0000BB"><?php </span><span style="color: #007700">echo </span><span style="color: #0000BB">$article_current</span><span style="color: #007700">-></span><span style="color: #0000BB">seo_url</span><span style="color: #007700">; </span><span style="color: #0000BB">?></span>.html"/> </span></code></span> <code><span style="color: #000000"><span style="color: #0000BB"> </span><span style="color: #007700"><</span><span style="color: #0000BB">meta http</span><span style="color: #007700">-</span><span style="color: #0000BB">equiv</span><span style="color: #007700">=</span><span style="color: #DD0000">"Content-Type" </span><span style="color: #0000BB">content</span><span style="color: #007700">=</span><span style="color: #DD0000">"text/html; charset=utf-8"</span><span style="color: #007700">/> </span></span></code></pre><pre id="cakeErr68030c5f75e61-context" class="cake-context" style="display: none;">$viewFile = '/home/brlfuser/public_html/src/Template/Layout/printlayout.ctp' $dataForView = [ 'article_current' => object(App\Model\Entity\Article) { 'id' => (int) 27028, 'title' => 'Fillip to cheaper hepatitis C drug -GS Mudur', 'subheading' => '', 'description' => '<div align="justify"> -The Telegraph </div> <p align="justify"> <em>New Delhi: </em>India's patent regulating agency today rejected a US company's patent claim on a drug to treat hepatitis C, raising hopes that generic drug makers could now produce cheaper versions of the medicine. </p> <p align="justify"> The Indian Patents Controller has denied a patent to sofosbuvir from Gilead, a US biopharmaceutical company that had last year pledged to make the oral drug available in India and 90 other developing countries at $900 (Rs 55,600) for a 12-week course of treatment. </p> <p align="justify"> The decision will allow generic drug makers to manufacture their own low-cost versions of the medicine. A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment. </p> <p align="justify"> &quot;This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price,&quot; said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs. </p> <p align="justify"> Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900. </p> <p align="justify"> It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. But patients' rights groups believe the drug would remain out of reach of most Indian patients even at those lowered prices. </p> <p align="justify"> The MSF Access Campaign plans to expand treatment for hepatitis C in India and eight other developing countries. It has been hoping for inexpensive versions of the medicine that it expects will remain the &quot;backbone of (the) hepatitis C treatment regimen in the coming years&quot;. </p> <p align="justify"> Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin. </p> <p align="justify"> But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir. </p> <p align="justify"> &quot;We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment,&quot; said Andrew Hill, a senior research fellow at Liverpool University in the UK. </p> <p align="justify"> Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several &quot;direct-acting&quot; anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course. </p> <p align="justify"> The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. 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A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment.</p><p align="justify">&quot;This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price,&quot; said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs.</p><p align="justify">Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900.</p><p align="justify">It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. 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A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment. </p> <p align="justify"> &quot;This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price,&quot; said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs. </p> <p align="justify"> Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900. </p> <p align="justify"> It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. 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It has been hoping for inexpensive versions of the medicine that it expects will remain the &quot;backbone of (the) hepatitis C treatment regimen in the coming years&quot;. </p> <p align="justify"> Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin. </p> <p align="justify"> But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir. </p> <p align="justify"> &quot;We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment,&quot; said Andrew Hill, a senior research fellow at Liverpool University in the UK. </p> <p align="justify"> Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several &quot;direct-acting&quot; anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course. </p> <p align="justify"> The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. 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A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment.</p><p align="justify">&quot;This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price,&quot; said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs.</p><p align="justify">Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900.</p><p align="justify">It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. 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Many health activists regard this clause as a safeguard.</p><p align="justify">Gilead has the right to move an appeal with the patent authority or approach an Indian court.</p>' $lang = 'English' $SITE_URL = 'https://im4change.in/' $site_title = 'im4change' $adminprix = 'admin'</pre><pre class="stack-trace">include - APP/Template/Layout/printlayout.ctp, line 8 Cake\View\View::_evaluate() - CORE/src/View/View.php, line 1413 Cake\View\View::_render() - CORE/src/View/View.php, line 1374 Cake\View\View::renderLayout() - CORE/src/View/View.php, line 927 Cake\View\View::render() - CORE/src/View/View.php, line 885 Cake\Controller\Controller::render() - CORE/src/Controller/Controller.php, line 791 Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 126 Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94 Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51</pre></div></pre>latest-news-updates/fillip-to-cheaper-hepatitis-c-drug-gs-mudur-4675073.html"/> <meta http-equiv="Content-Type" content="text/html; charset=utf-8"/> <link href="https://im4change.in/css/control.css" rel="stylesheet" type="text/css" media="all"/> <title>LATEST NEWS UPDATES | Fillip to cheaper hepatitis C drug -GS Mudur | Im4change.org</title> <meta name="description" content=" -The Telegraph New Delhi: India's patent regulating agency today rejected a US company's patent claim on a drug to treat hepatitis C, raising hopes that generic drug makers could now produce cheaper versions of the medicine. The Indian Patents Controller has denied..."/> <script src="https://im4change.in/js/jquery-1.10.2.js"></script> <script type="text/javascript" src="https://im4change.in/js/jquery-migrate.min.js"></script> <script language="javascript" type="text/javascript"> $(document).ready(function () { var img = $("img")[0]; // Get my img elem var pic_real_width, pic_real_height; $("<img/>") // Make in memory copy of image to avoid css issues .attr("src", $(img).attr("src")) .load(function () { pic_real_width = this.width; // Note: $(this).width() will not pic_real_height = this.height; // work for in memory images. }); }); </script> <style type="text/css"> @media screen { div.divFooter { display: block; } } @media print { .printbutton { display: none !important; } } </style> </head> <body> <table cellpadding="0" cellspacing="0" border="0" width="98%" align="center"> <tr> <td class="top_bg"> <div class="divFooter"> <img src="https://im4change.in/images/logo1.jpg" height="59" border="0" alt="Resource centre on India's rural distress" style="padding-top:14px;"/> </div> </td> </tr> <tr> <td id="topspace"> </td> </tr> <tr id="topspace"> <td> </td> </tr> <tr> <td height="50" style="border-bottom:1px solid #000; padding-top:10px;" class="printbutton"> <form><input type="button" value=" Print this page " onclick="window.print();return false;"/></form> </td> </tr> <tr> <td width="100%"> <h1 class="news_headlines" style="font-style:normal"> <strong>Fillip to cheaper hepatitis C drug -GS Mudur</strong></h1> </td> </tr> <tr> <td width="100%" style="font-family:Arial, 'Segoe Script', 'Segoe UI', sans-serif, serif"><font size="3"> <div align="justify">-The Telegraph</div><p align="justify"><em>New Delhi: </em>India's patent regulating agency today rejected a US company's patent claim on a drug to treat hepatitis C, raising hopes that generic drug makers could now produce cheaper versions of the medicine.</p><p align="justify">The Indian Patents Controller has denied a patent to sofosbuvir from Gilead, a US biopharmaceutical company that had last year pledged to make the oral drug available in India and 90 other developing countries at $900 (Rs 55,600) for a 12-week course of treatment.</p><p align="justify">The decision will allow generic drug makers to manufacture their own low-cost versions of the medicine. A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment.</p><p align="justify">"This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price," said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs.</p><p align="justify">Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900.</p><p align="justify">It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. But patients' rights groups believe the drug would remain out of reach of most Indian patients even at those lowered prices.</p><p align="justify">The MSF Access Campaign plans to expand treatment for hepatitis C in India and eight other developing countries. It has been hoping for inexpensive versions of the medicine that it expects will remain the "backbone of (the) hepatitis C treatment regimen in the coming years".</p><p align="justify">Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin.</p><p align="justify">But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir.</p><p align="justify">"We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment," said Andrew Hill, a senior research fellow at Liverpool University in the UK.</p><p align="justify">Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several "direct-acting" anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course.</p><p align="justify">The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. Many health activists regard this clause as a safeguard.</p><p align="justify">Gilead has the right to move an appeal with the patent authority or approach an Indian court.</p> </font> </td> </tr> <tr> <td> </td> </tr> <tr> <td height="50" style="border-top:1px solid #000; border-bottom:1px solid #000;padding-top:10px;"> <form><input type="button" value=" Print this page " onclick="window.print();return false;"/></form> </td> </tr> </table></body> </html>' } $cookies = [] $values = [ (int) 0 => 'text/html; charset=UTF-8' ] $name = 'Content-Type' $first = true $value = 'text/html; charset=UTF-8'header - [internal], line ?? Cake\Http\ResponseEmitter::emitHeaders() - CORE/src/Http/ResponseEmitter.php, line 181 Cake\Http\ResponseEmitter::emit() - CORE/src/Http/ResponseEmitter.php, line 55 Cake\Http\Server::emit() - CORE/src/Http/Server.php, line 141 [main] - ROOT/webroot/index.php, line 39
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A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment. </p> <p align="justify"> "This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price," said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs. </p> <p align="justify"> Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900. </p> <p align="justify"> It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. But patients' rights groups believe the drug would remain out of reach of most Indian patients even at those lowered prices. </p> <p align="justify"> The MSF Access Campaign plans to expand treatment for hepatitis C in India and eight other developing countries. It has been hoping for inexpensive versions of the medicine that it expects will remain the "backbone of (the) hepatitis C treatment regimen in the coming years". </p> <p align="justify"> Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin. </p> <p align="justify"> But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir. </p> <p align="justify"> "We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment," said Andrew Hill, a senior research fellow at Liverpool University in the UK. </p> <p align="justify"> Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several "direct-acting" anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course. </p> <p align="justify"> The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. 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A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment.</p><p align="justify">"This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price," said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs.</p><p align="justify">Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900.</p><p align="justify">It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. But patients' rights groups believe the drug would remain out of reach of most Indian patients even at those lowered prices.</p><p align="justify">The MSF Access Campaign plans to expand treatment for hepatitis C in India and eight other developing countries. It has been hoping for inexpensive versions of the medicine that it expects will remain the "backbone of (the) hepatitis C treatment regimen in the coming years".</p><p align="justify">Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin.</p><p align="justify">But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir.</p><p align="justify">"We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment," said Andrew Hill, a senior research fellow at Liverpool University in the UK.</p><p align="justify">Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several "direct-acting" anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course.</p><p align="justify">The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. 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A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment. </p> <p align="justify"> "This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price," said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs. </p> <p align="justify"> Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900. </p> <p align="justify"> It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. 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A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment.</p><p align="justify">"This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price," said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs.</p><p align="justify">Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900.</p><p align="justify">It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. But patients' rights groups believe the drug would remain out of reach of most Indian patients even at those lowered prices.</p><p align="justify">The MSF Access Campaign plans to expand treatment for hepatitis C in India and eight other developing countries. It has been hoping for inexpensive versions of the medicine that it expects will remain the "backbone of (the) hepatitis C treatment regimen in the coming years".</p><p align="justify">Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin.</p><p align="justify">But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir.</p><p align="justify">"We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment," said Andrew Hill, a senior research fellow at Liverpool University in the UK.</p><p align="justify">Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several "direct-acting" anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course.</p><p align="justify">The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. 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Fillip to cheaper hepatitis C drug -GS Mudur |
-The Telegraph New Delhi: India's patent regulating agency today rejected a US company's patent claim on a drug to treat hepatitis C, raising hopes that generic drug makers could now produce cheaper versions of the medicine. The Indian Patents Controller has denied a patent to sofosbuvir from Gilead, a US biopharmaceutical company that had last year pledged to make the oral drug available in India and 90 other developing countries at $900 (Rs 55,600) for a 12-week course of treatment. The decision will allow generic drug makers to manufacture their own low-cost versions of the medicine. A research study by scientists at the University of Liverpool, published last year, had calculated that the medicine could be produced for only $101 (Rs 6,240) for the 12-week course of treatment. "This drug makes hepatitis C treatment more effective. We're hoping this decision opens the floodgates for more open competition that could rapidly lower the price," said Manica Balasegaram, executive director with the Medecins Sans Frontieres' (MSF) Access Campaign, a humanitarian initiative to expand access to drugs. Sofosbuvir is available in the US for $84,000 (Rs 51.9 lakh) for a course of treatment but Gilead - while awaiting a decision from India's patent office - had last September announced that it would sell the drug in India at $900. It had also signed pacts with seven Indian drug companies, allowing them to sell generic versions of the drug at even lower prices. But patients' rights groups believe the drug would remain out of reach of most Indian patients even at those lowered prices. The MSF Access Campaign plans to expand treatment for hepatitis C in India and eight other developing countries. It has been hoping for inexpensive versions of the medicine that it expects will remain the "backbone of (the) hepatitis C treatment regimen in the coming years". Currently, treatment for the hepatitis C viral infection involves an injectable product called pegylated interferon with an anti-viral drug called ribavarin. But, an MSF official said, the success rate of the pegylated interferon regimen in eliminating the infection is about 70 per cent, while it is over 90 per cent with sofosbuvir. "We know from various manufacturers in India that they could produce this drug in future for as little as $101 for a three-month course of treatment," said Andrew Hill, a senior research fellow at Liverpool University in the UK. Hill and his colleagues had last year published a study in the journal Clinical Infectious Diseases in which they had estimated that the manufacturing costs of several "direct-acting" anti-viral drugs, sofosbuvir among them, could range between $100 and $250 for a 12-week treatment course. The patent examiners denied the patent claim citing Section 3(d) of India's patent act, which disallows patents on new or tweaked versions of known or old drug molecules. Many health activists regard this clause as a safeguard. Gilead has the right to move an appeal with the patent authority or approach an Indian court. |