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Genome sequencing: Govt deviates from target set by national research consortium -GS Mudur

-The Telegraph

Health ministry asks for 15 samples each from five labs and five hospitals in every state every two weeks, which is less than the 5% prescribed for each state

The Union health ministry has asked each state to send 150 Covid-positive samples fortnightly for genome sequencing, deviating from the original target set by a national research consortium to genome-sequence 5 per cent of positive cases from all states.

The move has baffled many health researchers who say the new guidelines have lowered the genome-sequencing target at a time the emerging coronavirus variants need intense scrutiny.

The health ministry’s guidelines seek 15 samples each from five labs and five hospitals in every state every two weeks.

Some health and medical researchers are concerned that a uniform flow of 300 sequences a month from each state would not provide sufficient data to determine how the “variants of interest” might be affecting the patterns of infections or the epidemic there.

“The fewer samples we sequence, the less we know what the variants are exactly doing in India,” said a senior researcher in one of the 10 labs that make up the Indian National SARS-CoV-2 Genomics Consortium (Insacog), established by the Centre in January this year.

The 10 central government labs that make up the consortium have sequenced over 20,000 samples from across India and found that some variants are dominating certain geographic regions — one named B.1.617 in Maharashtra, for instance, and another called B.1.618 in Bengal.

The fast-spreading UK variant, B.1.117, appears to be dominating samples sequenced from Punjab, Delhi and Haryana; B.1.617 accounts for 35 to 40 per cent of the samples from Maharashtra; while B.1.618 makes up roughly 20 per cent of the samples in Bengal.

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