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Indian scientists' study show how Vitamin D deficiency can cause heart failure -Dinesh C Sharma

-The Hindu Business Line

A daily dose of sunshine, which stimulates production of Vitamin D in the body, is vital not just for the wellbeing of your bones but may also be good for your heart.

The problem of vitamin D deficiency affecting bone health is well known for decades. For some years, scientists have also seen vitamin D deficiency as a factor that determines health of your heart. Now Indian researchers have deciphered how exactly vitamin D deficiency can cause heart failure.

The new study has shown that vitamin D deficiency alone can lead to heart failure, possibly through insulin resistance. It has found that cardiac insulin leads to functional deterioration of heart in animals with low vitamin D levels. The utilization of glucose and fatty acids - key fuels for energy generation in heart - is adversely affected due to insulin resistance in heart cells.

Insulin plays a critical role in regulation of cellular metabolism in many tissues in the body.

To study if vitamin D deficiency could cause cardiac damage similar to other risk factors like consumption of high fats and high calorie food, researchers designed an experiment with rats.

They manipulated diets of animals and divided them into three groups – one with adequate vitamin D, second set had vitamin D deficiency, while the third group was fed with high fat and high fructose diet.

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