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Monkeypox symptoms, contagious phase can reduce with antiviral drugs, finds Lancet study

-IndiaToday.in

A study published in the prestigious medical journal Lancet has found that some antiviral medications might have the potential to shorten symptoms of monkeypox and reduce the amount of time a patient is contagious.

Nearly 20 countries where monkeypox is not endemic have reported outbreaks of the viral disease, with more than 100 confirmed or suspected infections mostly in Europe. The outbreaks are raising alarm because monkeypox, which spreads through close contact and was first found in monkeys, mostly occurs in west and central Africa, and only very occasionally spreads elsewhere.

The World Health Organisation has assured that the outbreak of monkeypox cases outside of Africa can be contained as more governments said they would launch limited vaccinations to combat rising infections of the virus.

ANTIVIRAL MEDICATIONS MIGHT HELP

Some antiviral medications might have the potential to shorten symptoms of monkeypox and reduce the amount of time a patient is contagious, according to a study of seven patients diagnosed with the rare viral disease in the UK between 2018 and 2021.

The cases analysed in the study, published on Tuesday in The Lancet Infectious Diseases journal, represent the first instances of in-hospital transmission and household transmission outside of Africa.

The research also reported the patient response to the first off-label use of two different antiviral medications -- brincidofovir and tecovirimat -- to treat the disease.

The study found little evidence that brincidofovir was of clinical benefit but concluded that further research into the potential of tecovirimat would be warranted.

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