Deprecated (16384): The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 73 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php. [CORE/src/Core/functions.php, line 311]Code Context
trigger_error($message, E_USER_DEPRECATED);
}
$message = 'The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 73 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php.' $stackFrame = (int) 1 $trace = [ (int) 0 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ServerRequest.php', 'line' => (int) 2421, 'function' => 'deprecationWarning', 'args' => [ (int) 0 => 'The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead.' ] ], (int) 1 => [ 'file' => '/home/brlfuser/public_html/src/Controller/ArtileDetailController.php', 'line' => (int) 73, 'function' => 'offsetGet', 'class' => 'Cake\Http\ServerRequest', 'object' => object(Cake\Http\ServerRequest) {}, 'type' => '->', 'args' => [ (int) 0 => 'catslug' ] ], (int) 2 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Controller/Controller.php', 'line' => (int) 610, 'function' => 'printArticle', 'class' => 'App\Controller\ArtileDetailController', 'object' => object(App\Controller\ArtileDetailController) {}, 'type' => '->', 'args' => [] ], (int) 3 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ActionDispatcher.php', 'line' => (int) 120, 'function' => 'invokeAction', 'class' => 'Cake\Controller\Controller', 'object' => object(App\Controller\ArtileDetailController) {}, 'type' => '->', 'args' => [] ], (int) 4 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ActionDispatcher.php', 'line' => (int) 94, 'function' => '_invoke', 'class' => 'Cake\Http\ActionDispatcher', 'object' => object(Cake\Http\ActionDispatcher) {}, 'type' => '->', 'args' => [ (int) 0 => object(App\Controller\ArtileDetailController) {} ] ], (int) 5 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/BaseApplication.php', 'line' => (int) 235, 'function' => 'dispatch', 'class' => 'Cake\Http\ActionDispatcher', 'object' => object(Cake\Http\ActionDispatcher) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 6 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Http\BaseApplication', 'object' => object(App\Application) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 7 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Routing/Middleware/RoutingMiddleware.php', 'line' => (int) 162, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 8 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Routing\Middleware\RoutingMiddleware', 'object' => object(Cake\Routing\Middleware\RoutingMiddleware) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 9 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Routing/Middleware/AssetMiddleware.php', 'line' => (int) 88, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 10 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Routing\Middleware\AssetMiddleware', 'object' => object(Cake\Routing\Middleware\AssetMiddleware) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 11 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Middleware/ErrorHandlerMiddleware.php', 'line' => (int) 96, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 12 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Error\Middleware\ErrorHandlerMiddleware', 'object' => object(Cake\Error\Middleware\ErrorHandlerMiddleware) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 13 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 51, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 14 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Server.php', 'line' => (int) 98, 'function' => 'run', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\MiddlewareQueue) {}, (int) 1 => object(Cake\Http\ServerRequest) {}, (int) 2 => object(Cake\Http\Response) {} ] ], (int) 15 => [ 'file' => '/home/brlfuser/public_html/webroot/index.php', 'line' => (int) 39, 'function' => 'run', 'class' => 'Cake\Http\Server', 'object' => object(Cake\Http\Server) {}, 'type' => '->', 'args' => [] ] ] $frame = [ 'file' => '/home/brlfuser/public_html/src/Controller/ArtileDetailController.php', 'line' => (int) 73, 'function' => 'offsetGet', 'class' => 'Cake\Http\ServerRequest', 'object' => object(Cake\Http\ServerRequest) { trustProxy => false [protected] params => [ [maximum depth reached] ] [protected] data => [[maximum depth reached]] [protected] query => [[maximum depth reached]] [protected] cookies => [ [maximum depth reached] ] [protected] _environment => [ [maximum depth reached] ] [protected] url => 'latest-news-updates/pills-and-shills-15266/print' [protected] base => '' [protected] webroot => '/' [protected] here => '/latest-news-updates/pills-and-shills-15266/print' [protected] trustedProxies => [[maximum depth reached]] [protected] _input => null [protected] _detectors => [ [maximum depth reached] ] [protected] _detectorCache => [ [maximum depth reached] ] [protected] stream => object(Zend\Diactoros\PhpInputStream) {} [protected] uri => object(Zend\Diactoros\Uri) {} [protected] session => object(Cake\Http\Session) {} [protected] attributes => [[maximum depth reached]] [protected] emulatedAttributes => [ [maximum depth reached] ] [protected] uploadedFiles => [[maximum depth reached]] [protected] protocol => null [protected] requestTarget => null [private] deprecatedProperties => [ [maximum depth reached] ] }, 'type' => '->', 'args' => [ (int) 0 => 'catslug' ] ]deprecationWarning - CORE/src/Core/functions.php, line 311 Cake\Http\ServerRequest::offsetGet() - CORE/src/Http/ServerRequest.php, line 2421 App\Controller\ArtileDetailController::printArticle() - APP/Controller/ArtileDetailController.php, line 73 Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 610 Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 120 Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94 Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51 Cake\Http\Server::run() - CORE/src/Http/Server.php, line 98
Deprecated (16384): The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 74 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php. [CORE/src/Core/functions.php, line 311]Code Context
trigger_error($message, E_USER_DEPRECATED);
}
$message = 'The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 74 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php.' $stackFrame = (int) 1 $trace = [ (int) 0 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ServerRequest.php', 'line' => (int) 2421, 'function' => 'deprecationWarning', 'args' => [ (int) 0 => 'The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead.' ] ], (int) 1 => [ 'file' => '/home/brlfuser/public_html/src/Controller/ArtileDetailController.php', 'line' => (int) 74, 'function' => 'offsetGet', 'class' => 'Cake\Http\ServerRequest', 'object' => object(Cake\Http\ServerRequest) {}, 'type' => '->', 'args' => [ (int) 0 => 'artileslug' ] ], (int) 2 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Controller/Controller.php', 'line' => (int) 610, 'function' => 'printArticle', 'class' => 'App\Controller\ArtileDetailController', 'object' => object(App\Controller\ArtileDetailController) {}, 'type' => '->', 'args' => [] ], (int) 3 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ActionDispatcher.php', 'line' => (int) 120, 'function' => 'invokeAction', 'class' => 'Cake\Controller\Controller', 'object' => object(App\Controller\ArtileDetailController) {}, 'type' => '->', 'args' => [] ], (int) 4 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/ActionDispatcher.php', 'line' => (int) 94, 'function' => '_invoke', 'class' => 'Cake\Http\ActionDispatcher', 'object' => object(Cake\Http\ActionDispatcher) {}, 'type' => '->', 'args' => [ (int) 0 => object(App\Controller\ArtileDetailController) {} ] ], (int) 5 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/BaseApplication.php', 'line' => (int) 235, 'function' => 'dispatch', 'class' => 'Cake\Http\ActionDispatcher', 'object' => object(Cake\Http\ActionDispatcher) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 6 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Http\BaseApplication', 'object' => object(App\Application) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 7 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Routing/Middleware/RoutingMiddleware.php', 'line' => (int) 162, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 8 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Routing\Middleware\RoutingMiddleware', 'object' => object(Cake\Routing\Middleware\RoutingMiddleware) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 9 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Routing/Middleware/AssetMiddleware.php', 'line' => (int) 88, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 10 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Routing\Middleware\AssetMiddleware', 'object' => object(Cake\Routing\Middleware\AssetMiddleware) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 11 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Middleware/ErrorHandlerMiddleware.php', 'line' => (int) 96, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 12 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 65, 'function' => '__invoke', 'class' => 'Cake\Error\Middleware\ErrorHandlerMiddleware', 'object' => object(Cake\Error\Middleware\ErrorHandlerMiddleware) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {}, (int) 2 => object(Cake\Http\Runner) {} ] ], (int) 13 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Runner.php', 'line' => (int) 51, 'function' => '__invoke', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\ServerRequest) {}, (int) 1 => object(Cake\Http\Response) {} ] ], (int) 14 => [ 'file' => '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Http/Server.php', 'line' => (int) 98, 'function' => 'run', 'class' => 'Cake\Http\Runner', 'object' => object(Cake\Http\Runner) {}, 'type' => '->', 'args' => [ (int) 0 => object(Cake\Http\MiddlewareQueue) {}, (int) 1 => object(Cake\Http\ServerRequest) {}, (int) 2 => object(Cake\Http\Response) {} ] ], (int) 15 => [ 'file' => '/home/brlfuser/public_html/webroot/index.php', 'line' => (int) 39, 'function' => 'run', 'class' => 'Cake\Http\Server', 'object' => object(Cake\Http\Server) {}, 'type' => '->', 'args' => [] ] ] $frame = [ 'file' => '/home/brlfuser/public_html/src/Controller/ArtileDetailController.php', 'line' => (int) 74, 'function' => 'offsetGet', 'class' => 'Cake\Http\ServerRequest', 'object' => object(Cake\Http\ServerRequest) { trustProxy => false [protected] params => [ [maximum depth reached] ] [protected] data => [[maximum depth reached]] [protected] query => [[maximum depth reached]] [protected] cookies => [ [maximum depth reached] ] [protected] _environment => [ [maximum depth reached] ] [protected] url => 'latest-news-updates/pills-and-shills-15266/print' [protected] base => '' [protected] webroot => '/' [protected] here => '/latest-news-updates/pills-and-shills-15266/print' [protected] trustedProxies => [[maximum depth reached]] [protected] _input => null [protected] _detectors => [ [maximum depth reached] ] [protected] _detectorCache => [ [maximum depth reached] ] [protected] stream => object(Zend\Diactoros\PhpInputStream) {} [protected] uri => object(Zend\Diactoros\Uri) {} [protected] session => object(Cake\Http\Session) {} [protected] attributes => [[maximum depth reached]] [protected] emulatedAttributes => [ [maximum depth reached] ] [protected] uploadedFiles => [[maximum depth reached]] [protected] protocol => null [protected] requestTarget => null [private] deprecatedProperties => [ [maximum depth reached] ] }, 'type' => '->', 'args' => [ (int) 0 => 'artileslug' ] ]deprecationWarning - CORE/src/Core/functions.php, line 311 Cake\Http\ServerRequest::offsetGet() - CORE/src/Http/ServerRequest.php, line 2421 App\Controller\ArtileDetailController::printArticle() - APP/Controller/ArtileDetailController.php, line 74 Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 610 Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 120 Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94 Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51 Cake\Http\Server::run() - CORE/src/Http/Server.php, line 98
Warning (512): Unable to emit headers. Headers sent in file=/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php line=853 [CORE/src/Http/ResponseEmitter.php, line 48]Code Contextif (Configure::read('debug')) {
trigger_error($message, E_USER_WARNING);
} else {
$response = object(Cake\Http\Response) { 'status' => (int) 200, 'contentType' => 'text/html', 'headers' => [ 'Content-Type' => [ [maximum depth reached] ] ], 'file' => null, 'fileRange' => [], 'cookies' => object(Cake\Http\Cookie\CookieCollection) {}, 'cacheDirectives' => [], 'body' => '<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd"> <html xmlns="http://www.w3.org/1999/xhtml"> <head> <link rel="canonical" href="https://im4change.in/<pre class="cake-error"><a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f96a4a61489-trace').style.display = (document.getElementById('cakeErr67f96a4a61489-trace').style.display == 'none' ? '' : 'none');"><b>Notice</b> (8)</a>: Undefined variable: urlPrefix [<b>APP/Template/Layout/printlayout.ctp</b>, line <b>8</b>]<div id="cakeErr67f96a4a61489-trace" class="cake-stack-trace" style="display: none;"><a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f96a4a61489-code').style.display = (document.getElementById('cakeErr67f96a4a61489-code').style.display == 'none' ? '' : 'none')">Code</a> <a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f96a4a61489-context').style.display = (document.getElementById('cakeErr67f96a4a61489-context').style.display == 'none' ? '' : 'none')">Context</a><pre id="cakeErr67f96a4a61489-code" class="cake-code-dump" style="display: none;"><code><span style="color: #000000"><span style="color: #0000BB"></span><span style="color: #007700"><</span><span style="color: #0000BB">head</span><span style="color: #007700">> </span></span></code> <span class="code-highlight"><code><span style="color: #000000"> <link rel="canonical" href="<span style="color: #0000BB"><?php </span><span style="color: #007700">echo </span><span style="color: #0000BB">Configure</span><span style="color: #007700">::</span><span style="color: #0000BB">read</span><span style="color: #007700">(</span><span style="color: #DD0000">'SITE_URL'</span><span style="color: #007700">); </span><span style="color: #0000BB">?><?php </span><span style="color: #007700">echo </span><span style="color: #0000BB">$urlPrefix</span><span style="color: #007700">;</span><span style="color: #0000BB">?><?php </span><span style="color: #007700">echo </span><span style="color: #0000BB">$article_current</span><span style="color: #007700">-></span><span style="color: #0000BB">category</span><span style="color: #007700">-></span><span style="color: #0000BB">slug</span><span style="color: #007700">; </span><span style="color: #0000BB">?></span>/<span style="color: #0000BB"><?php </span><span style="color: #007700">echo </span><span style="color: #0000BB">$article_current</span><span style="color: #007700">-></span><span style="color: #0000BB">seo_url</span><span style="color: #007700">; </span><span style="color: #0000BB">?></span>.html"/> </span></code></span> <code><span style="color: #000000"><span style="color: #0000BB"> </span><span style="color: #007700"><</span><span style="color: #0000BB">meta http</span><span style="color: #007700">-</span><span style="color: #0000BB">equiv</span><span style="color: #007700">=</span><span style="color: #DD0000">"Content-Type" </span><span style="color: #0000BB">content</span><span style="color: #007700">=</span><span style="color: #DD0000">"text/html; charset=utf-8"</span><span style="color: #007700">/> </span></span></code></pre><pre id="cakeErr67f96a4a61489-context" class="cake-context" style="display: none;">$viewFile = '/home/brlfuser/public_html/src/Template/Layout/printlayout.ctp' $dataForView = [ 'article_current' => object(App\Model\Entity\Article) { 'id' => (int) 15141, 'title' => 'Pills and shills', 'subheading' => '', 'description' => '<p> -The Indian Express </p> <div align="justify"> <em>Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame<br /> </em><br /> Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion between the regulator, industry and the medical profession that puts patients last. Over 118 pages, it said that the Drug Controller General of India (DCGI) and the Drug Standards Control Organisation (DSCO) have betrayed their regulatory responsibility in the manner in which they granted approvals. Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors&rsquo; opinions are irrelevant to the introduction of drugs in the Indian market.<br /> <br /> Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis&rsquo;s Everolimus, Eli Lilly&rsquo;s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a &ldquo;public interest&rdquo; escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. When expert opinion was consulted, it was seemingly dictated by what the report calls the &ldquo;invisible hand&rdquo; of pharma companies, sometimes the testimonials echoing each other word-for-word. In one case, with Thermis Medicare Ltd, the regulator asked the company to select its own experts, and bring their opinion to it. To be fair, there are reasons for this sloppiness &mdash; while the pharma industry is exploding, and the DSCO&rsquo;s workload is growing by 20 per cent every year, it lacks the staff and infrastructure, advisers and independent testing labs to do its job. <br /> <br /> This is not a moment to blame each other. Doctors have been part of this corrupt edifice, along with companies and regulatory officials. Medicines, after all, are an area where consumers are not equipped to make informed decisions. They rely on those who know better to look out for their interests. 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Everyone who propped up this irresponsible system is to blame Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion...', 'disp' => '<p>-The Indian Express</p><div align="justify"><em>Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame<br /></em><br />Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion between the regulator, industry and the medical profession that puts patients last. Over 118 pages, it said that the Drug Controller General of India (DCGI) and the Drug Standards Control Organisation (DSCO) have betrayed their regulatory responsibility in the manner in which they granted approvals. Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors&rsquo; opinions are irrelevant to the introduction of drugs in the Indian market.<br /><br />Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis&rsquo;s Everolimus, Eli Lilly&rsquo;s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a &ldquo;public interest&rdquo; escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. When expert opinion was consulted, it was seemingly dictated by what the report calls the &ldquo;invisible hand&rdquo; of pharma companies, sometimes the testimonials echoing each other word-for-word. In one case, with Thermis Medicare Ltd, the regulator asked the company to select its own experts, and bring their opinion to it. To be fair, there are reasons for this sloppiness &mdash; while the pharma industry is exploding, and the DSCO&rsquo;s workload is growing by 20 per cent every year, it lacks the staff and infrastructure, advisers and independent testing labs to do its job. <br /><br />This is not a moment to blame each other. Doctors have been part of this corrupt edifice, along with companies and regulatory officials. Medicines, after all, are an area where consumers are not equipped to make informed decisions. They rely on those who know better to look out for their interests. 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Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors&rsquo; opinions are irrelevant to the introduction of drugs in the Indian market.<br /> <br /> Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis&rsquo;s Everolimus, Eli Lilly&rsquo;s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a &ldquo;public interest&rdquo; escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. 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And they have been sorely let down. <br /> </div>', 'credit_writer' => 'The Indian Express, 21 May, 2012, http://www.indianexpress.com/news/pills-and-shills/951687/', 'article_img' => '', 'article_img_thumb' => '', 'status' => (int) 1, 'show_on_home' => (int) 1, 'lang' => 'EN', 'category_id' => (int) 16, 'tag_keyword' => '', 'seo_url' => 'pills-and-shills-15266', 'meta_title' => null, 'meta_keywords' => null, 'meta_description' => null, 'noindex' => (int) 0, 'publish_date' => object(Cake\I18n\FrozenDate) {}, 'most_visit_section_id' => null, 'article_big_img' => null, 'liveid' => (int) 15266, 'created' => object(Cake\I18n\FrozenTime) {}, 'modified' => object(Cake\I18n\FrozenTime) {}, 'edate' => '', 'tags' => [ (int) 0 => object(Cake\ORM\Entity) {}, (int) 1 => object(Cake\ORM\Entity) {} ], 'category' => object(App\Model\Entity\Category) {}, '[new]' => false, '[accessible]' => [ '*' => true, 'id' => false ], '[dirty]' => [], '[original]' => [], '[virtual]' => [], '[hasErrors]' => false, '[errors]' => [], '[invalid]' => [], '[repository]' => 'Articles' } $articleid = (int) 15141 $metaTitle = 'LATEST NEWS UPDATES | Pills and shills' $metaKeywords = 'medicines,Health' $metaDesc = ' -The Indian Express Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion...' $disp = '<p>-The Indian Express</p><div align="justify"><em>Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame<br /></em><br />Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion between the regulator, industry and the medical profession that puts patients last. Over 118 pages, it said that the Drug Controller General of India (DCGI) and the Drug Standards Control Organisation (DSCO) have betrayed their regulatory responsibility in the manner in which they granted approvals. Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors&rsquo; opinions are irrelevant to the introduction of drugs in the Indian market.<br /><br />Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis&rsquo;s Everolimus, Eli Lilly&rsquo;s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a &ldquo;public interest&rdquo; escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. When expert opinion was consulted, it was seemingly dictated by what the report calls the &ldquo;invisible hand&rdquo; of pharma companies, sometimes the testimonials echoing each other word-for-word. In one case, with Thermis Medicare Ltd, the regulator asked the company to select its own experts, and bring their opinion to it. To be fair, there are reasons for this sloppiness &mdash; while the pharma industry is exploding, and the DSCO&rsquo;s workload is growing by 20 per cent every year, it lacks the staff and infrastructure, advisers and independent testing labs to do its job. <br /><br />This is not a moment to blame each other. Doctors have been part of this corrupt edifice, along with companies and regulatory officials. Medicines, after all, are an area where consumers are not equipped to make informed decisions. They rely on those who know better to look out for their interests. And they have been sorely let down. <br /></div>' $lang = 'English' $SITE_URL = 'https://im4change.in/' $site_title = 'im4change' $adminprix = 'admin'</pre><pre class="stack-trace">include - APP/Template/Layout/printlayout.ctp, line 8 Cake\View\View::_evaluate() - CORE/src/View/View.php, line 1413 Cake\View\View::_render() - CORE/src/View/View.php, line 1374 Cake\View\View::renderLayout() - CORE/src/View/View.php, line 927 Cake\View\View::render() - CORE/src/View/View.php, line 885 Cake\Controller\Controller::render() - CORE/src/Controller/Controller.php, line 791 Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 126 Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94 Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51</pre></div></pre>latest-news-updates/pills-and-shills-15266.html"/> <meta http-equiv="Content-Type" content="text/html; charset=utf-8"/> <link href="https://im4change.in/css/control.css" rel="stylesheet" type="text/css" media="all"/> <title>LATEST NEWS UPDATES | Pills and shills | Im4change.org</title> <meta name="description" content=" -The Indian Express Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion..."/> <script src="https://im4change.in/js/jquery-1.10.2.js"></script> <script type="text/javascript" src="https://im4change.in/js/jquery-migrate.min.js"></script> <script language="javascript" type="text/javascript"> $(document).ready(function () { var img = $("img")[0]; // Get my img elem var pic_real_width, pic_real_height; $("<img/>") // Make in memory copy of image to avoid css issues .attr("src", $(img).attr("src")) .load(function () { pic_real_width = this.width; // Note: $(this).width() will not pic_real_height = this.height; // work for in memory images. }); }); </script> <style type="text/css"> @media screen { div.divFooter { display: block; } } @media print { .printbutton { display: none !important; } } </style> </head> <body> <table cellpadding="0" cellspacing="0" border="0" width="98%" align="center"> <tr> <td class="top_bg"> <div class="divFooter"> <img src="https://im4change.in/images/logo1.jpg" height="59" border="0" alt="Resource centre on India's rural distress" style="padding-top:14px;"/> </div> </td> </tr> <tr> <td id="topspace"> </td> </tr> <tr id="topspace"> <td> </td> </tr> <tr> <td height="50" style="border-bottom:1px solid #000; padding-top:10px;" class="printbutton"> <form><input type="button" value=" Print this page " onclick="window.print();return false;"/></form> </td> </tr> <tr> <td width="100%"> <h1 class="news_headlines" style="font-style:normal"> <strong>Pills and shills</strong></h1> </td> </tr> <tr> <td width="100%" style="font-family:Arial, 'Segoe Script', 'Segoe UI', sans-serif, serif"><font size="3"> <p>-The Indian Express</p><div align="justify"><em>Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame<br /></em><br />Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion between the regulator, industry and the medical profession that puts patients last. Over 118 pages, it said that the Drug Controller General of India (DCGI) and the Drug Standards Control Organisation (DSCO) have betrayed their regulatory responsibility in the manner in which they granted approvals. Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors’ opinions are irrelevant to the introduction of drugs in the Indian market.<br /><br />Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis’s Everolimus, Eli Lilly’s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a “public interest” escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. When expert opinion was consulted, it was seemingly dictated by what the report calls the “invisible hand” of pharma companies, sometimes the testimonials echoing each other word-for-word. In one case, with Thermis Medicare Ltd, the regulator asked the company to select its own experts, and bring their opinion to it. To be fair, there are reasons for this sloppiness — while the pharma industry is exploding, and the DSCO’s workload is growing by 20 per cent every year, it lacks the staff and infrastructure, advisers and independent testing labs to do its job. <br /><br />This is not a moment to blame each other. Doctors have been part of this corrupt edifice, along with companies and regulatory officials. Medicines, after all, are an area where consumers are not equipped to make informed decisions. They rely on those who know better to look out for their interests. And they have been sorely let down. <br /></div> </font> </td> </tr> <tr> <td> </td> </tr> <tr> <td height="50" style="border-top:1px solid #000; border-bottom:1px solid #000;padding-top:10px;"> <form><input type="button" value=" Print this page " onclick="window.print();return false;"/></form> </td> </tr> </table></body> </html>' } $maxBufferLength = (int) 8192 $file = '/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php' $line = (int) 853 $message = 'Unable to emit headers. Headers sent in file=/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php line=853'Cake\Http\ResponseEmitter::emit() - CORE/src/Http/ResponseEmitter.php, line 48 Cake\Http\Server::emit() - CORE/src/Http/Server.php, line 141 [main] - ROOT/webroot/index.php, line 39
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$response = object(Cake\Http\Response) { 'status' => (int) 200, 'contentType' => 'text/html', 'headers' => [ 'Content-Type' => [ [maximum depth reached] ] ], 'file' => null, 'fileRange' => [], 'cookies' => object(Cake\Http\Cookie\CookieCollection) {}, 'cacheDirectives' => [], 'body' => '<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd"> <html xmlns="http://www.w3.org/1999/xhtml"> <head> <link rel="canonical" href="https://im4change.in/<pre class="cake-error"><a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f96a4a61489-trace').style.display = (document.getElementById('cakeErr67f96a4a61489-trace').style.display == 'none' ? '' : 'none');"><b>Notice</b> (8)</a>: Undefined variable: urlPrefix [<b>APP/Template/Layout/printlayout.ctp</b>, line <b>8</b>]<div id="cakeErr67f96a4a61489-trace" class="cake-stack-trace" style="display: none;"><a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f96a4a61489-code').style.display = (document.getElementById('cakeErr67f96a4a61489-code').style.display == 'none' ? '' : 'none')">Code</a> <a href="javascript:void(0);" onclick="document.getElementById('cakeErr67f96a4a61489-context').style.display = (document.getElementById('cakeErr67f96a4a61489-context').style.display == 'none' ? 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Everyone who propped up this irresponsible system is to blame<br /> </em><br /> Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion between the regulator, industry and the medical profession that puts patients last. Over 118 pages, it said that the Drug Controller General of India (DCGI) and the Drug Standards Control Organisation (DSCO) have betrayed their regulatory responsibility in the manner in which they granted approvals. Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors&rsquo; opinions are irrelevant to the introduction of drugs in the Indian market.<br /> <br /> Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis&rsquo;s Everolimus, Eli Lilly&rsquo;s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a &ldquo;public interest&rdquo; escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. When expert opinion was consulted, it was seemingly dictated by what the report calls the &ldquo;invisible hand&rdquo; of pharma companies, sometimes the testimonials echoing each other word-for-word. In one case, with Thermis Medicare Ltd, the regulator asked the company to select its own experts, and bring their opinion to it. 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Everyone who propped up this irresponsible system is to blame Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion...', 'disp' => '<p>-The Indian Express</p><div align="justify"><em>Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame<br /></em><br />Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion between the regulator, industry and the medical profession that puts patients last. Over 118 pages, it said that the Drug Controller General of India (DCGI) and the Drug Standards Control Organisation (DSCO) have betrayed their regulatory responsibility in the manner in which they granted approvals. Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors&rsquo; opinions are irrelevant to the introduction of drugs in the Indian market.<br /><br />Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis&rsquo;s Everolimus, Eli Lilly&rsquo;s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a &ldquo;public interest&rdquo; escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. 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Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors&rsquo; opinions are irrelevant to the introduction of drugs in the Indian market.<br /> <br /> Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis&rsquo;s Everolimus, Eli Lilly&rsquo;s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a &ldquo;public interest&rdquo; escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. When expert opinion was consulted, it was seemingly dictated by what the report calls the &ldquo;invisible hand&rdquo; of pharma companies, sometimes the testimonials echoing each other word-for-word. In one case, with Thermis Medicare Ltd, the regulator asked the company to select its own experts, and bring their opinion to it. To be fair, there are reasons for this sloppiness &mdash; while the pharma industry is exploding, and the DSCO&rsquo;s workload is growing by 20 per cent every year, it lacks the staff and infrastructure, advisers and independent testing labs to do its job. <br /> <br /> This is not a moment to blame each other. Doctors have been part of this corrupt edifice, along with companies and regulatory officials. Medicines, after all, are an area where consumers are not equipped to make informed decisions. They rely on those who know better to look out for their interests. And they have been sorely let down. <br /> </div>', 'credit_writer' => 'The Indian Express, 21 May, 2012, http://www.indianexpress.com/news/pills-and-shills/951687/', 'article_img' => '', 'article_img_thumb' => '', 'status' => (int) 1, 'show_on_home' => (int) 1, 'lang' => 'EN', 'category_id' => (int) 16, 'tag_keyword' => '', 'seo_url' => 'pills-and-shills-15266', 'meta_title' => null, 'meta_keywords' => null, 'meta_description' => null, 'noindex' => (int) 0, 'publish_date' => object(Cake\I18n\FrozenDate) {}, 'most_visit_section_id' => null, 'article_big_img' => null, 'liveid' => (int) 15266, 'created' => object(Cake\I18n\FrozenTime) {}, 'modified' => object(Cake\I18n\FrozenTime) {}, 'edate' => '', 'tags' => [ (int) 0 => object(Cake\ORM\Entity) {}, (int) 1 => object(Cake\ORM\Entity) {} ], 'category' => object(App\Model\Entity\Category) {}, '[new]' => false, '[accessible]' => [ '*' => true, 'id' => false ], '[dirty]' => [], '[original]' => [], '[virtual]' => [], '[hasErrors]' => false, '[errors]' => [], '[invalid]' => [], '[repository]' => 'Articles' } $articleid = (int) 15141 $metaTitle = 'LATEST NEWS UPDATES | Pills and shills' $metaKeywords = 'medicines,Health' $metaDesc = ' -The Indian Express Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion...' $disp = '<p>-The Indian Express</p><div align="justify"><em>Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame<br /></em><br />Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion between the regulator, industry and the medical profession that puts patients last. Over 118 pages, it said that the Drug Controller General of India (DCGI) and the Drug Standards Control Organisation (DSCO) have betrayed their regulatory responsibility in the manner in which they granted approvals. Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors&rsquo; opinions are irrelevant to the introduction of drugs in the Indian market.<br /><br />Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis&rsquo;s Everolimus, Eli Lilly&rsquo;s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a &ldquo;public interest&rdquo; escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. When expert opinion was consulted, it was seemingly dictated by what the report calls the &ldquo;invisible hand&rdquo; of pharma companies, sometimes the testimonials echoing each other word-for-word. In one case, with Thermis Medicare Ltd, the regulator asked the company to select its own experts, and bring their opinion to it. To be fair, there are reasons for this sloppiness &mdash; while the pharma industry is exploding, and the DSCO&rsquo;s workload is growing by 20 per cent every year, it lacks the staff and infrastructure, advisers and independent testing labs to do its job. <br /><br />This is not a moment to blame each other. Doctors have been part of this corrupt edifice, along with companies and regulatory officials. Medicines, after all, are an area where consumers are not equipped to make informed decisions. They rely on those who know better to look out for their interests. And they have been sorely let down. <br /></div>' $lang = 'English' $SITE_URL = 'https://im4change.in/' $site_title = 'im4change' $adminprix = 'admin'</pre><pre class="stack-trace">include - APP/Template/Layout/printlayout.ctp, line 8 Cake\View\View::_evaluate() - CORE/src/View/View.php, line 1413 Cake\View\View::_render() - CORE/src/View/View.php, line 1374 Cake\View\View::renderLayout() - CORE/src/View/View.php, line 927 Cake\View\View::render() - CORE/src/View/View.php, line 885 Cake\Controller\Controller::render() - CORE/src/Controller/Controller.php, line 791 Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 126 Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94 Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51</pre></div></pre>latest-news-updates/pills-and-shills-15266.html"/> <meta http-equiv="Content-Type" content="text/html; charset=utf-8"/> <link href="https://im4change.in/css/control.css" rel="stylesheet" type="text/css" media="all"/> <title>LATEST NEWS UPDATES | Pills and shills | Im4change.org</title> <meta name="description" content=" -The Indian Express Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion..."/> <script src="https://im4change.in/js/jquery-1.10.2.js"></script> <script type="text/javascript" src="https://im4change.in/js/jquery-migrate.min.js"></script> <script language="javascript" type="text/javascript"> $(document).ready(function () { var img = $("img")[0]; // Get my img elem var pic_real_width, pic_real_height; $("<img/>") // Make in memory copy of image to avoid css issues .attr("src", $(img).attr("src")) .load(function () { pic_real_width = this.width; // Note: $(this).width() will not pic_real_height = this.height; // work for in memory images. }); }); </script> <style type="text/css"> @media screen { div.divFooter { display: block; } } @media print { .printbutton { display: none !important; } } </style> </head> <body> <table cellpadding="0" cellspacing="0" border="0" width="98%" align="center"> <tr> <td class="top_bg"> <div class="divFooter"> <img src="https://im4change.in/images/logo1.jpg" height="59" border="0" alt="Resource centre on India's rural distress" style="padding-top:14px;"/> </div> </td> </tr> <tr> <td id="topspace"> </td> </tr> <tr id="topspace"> <td> </td> </tr> <tr> <td height="50" style="border-bottom:1px solid #000; padding-top:10px;" class="printbutton"> <form><input type="button" value=" Print this page " onclick="window.print();return false;"/></form> </td> </tr> <tr> <td width="100%"> <h1 class="news_headlines" style="font-style:normal"> <strong>Pills and shills</strong></h1> </td> </tr> <tr> <td width="100%" style="font-family:Arial, 'Segoe Script', 'Segoe UI', sans-serif, serif"><font size="3"> <p>-The Indian Express</p><div align="justify"><em>Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame<br /></em><br />Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion between the regulator, industry and the medical profession that puts patients last. Over 118 pages, it said that the Drug Controller General of India (DCGI) and the Drug Standards Control Organisation (DSCO) have betrayed their regulatory responsibility in the manner in which they granted approvals. Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors’ opinions are irrelevant to the introduction of drugs in the Indian market.<br /><br />Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis’s Everolimus, Eli Lilly’s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a “public interest” escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. When expert opinion was consulted, it was seemingly dictated by what the report calls the “invisible hand” of pharma companies, sometimes the testimonials echoing each other word-for-word. In one case, with Thermis Medicare Ltd, the regulator asked the company to select its own experts, and bring their opinion to it. To be fair, there are reasons for this sloppiness — while the pharma industry is exploding, and the DSCO’s workload is growing by 20 per cent every year, it lacks the staff and infrastructure, advisers and independent testing labs to do its job. <br /><br />This is not a moment to blame each other. Doctors have been part of this corrupt edifice, along with companies and regulatory officials. Medicines, after all, are an area where consumers are not equipped to make informed decisions. They rely on those who know better to look out for their interests. And they have been sorely let down. <br /></div> </font> </td> </tr> <tr> <td> </td> </tr> <tr> <td height="50" style="border-top:1px solid #000; border-bottom:1px solid #000;padding-top:10px;"> <form><input type="button" value=" Print this page " onclick="window.print();return false;"/></form> </td> </tr> </table></body> </html>' } $reasonPhrase = 'OK'header - [internal], line ?? 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Warning (2): Cannot modify header information - headers already sent by (output started at /home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php:853) [CORE/src/Http/ResponseEmitter.php, line 181]Notice (8): Undefined variable: urlPrefix [APP/Template/Layout/printlayout.ctp, line 8]Code Context$value
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Everyone who propped up this irresponsible system is to blame Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion...' $disp = '<p>-The Indian Express</p><div align="justify"><em>Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame<br /></em><br />Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion between the regulator, industry and the medical profession that puts patients last. Over 118 pages, it said that the Drug Controller General of India (DCGI) and the Drug Standards Control Organisation (DSCO) have betrayed their regulatory responsibility in the manner in which they granted approvals. Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors&rsquo; opinions are irrelevant to the introduction of drugs in the Indian market.<br /><br />Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis&rsquo;s Everolimus, Eli Lilly&rsquo;s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a &ldquo;public interest&rdquo; escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. When expert opinion was consulted, it was seemingly dictated by what the report calls the &ldquo;invisible hand&rdquo; of pharma companies, sometimes the testimonials echoing each other word-for-word. In one case, with Thermis Medicare Ltd, the regulator asked the company to select its own experts, and bring their opinion to it. To be fair, there are reasons for this sloppiness &mdash; while the pharma industry is exploding, and the DSCO&rsquo;s workload is growing by 20 per cent every year, it lacks the staff and infrastructure, advisers and independent testing labs to do its job. <br /><br />This is not a moment to blame each other. Doctors have been part of this corrupt edifice, along with companies and regulatory officials. Medicines, after all, are an area where consumers are not equipped to make informed decisions. They rely on those who know better to look out for their interests. And they have been sorely let down. <br /></div>' $lang = 'English' $SITE_URL = 'https://im4change.in/' $site_title = 'im4change' $adminprix = 'admin'</pre><pre class="stack-trace">include - APP/Template/Layout/printlayout.ctp, line 8 Cake\View\View::_evaluate() - CORE/src/View/View.php, line 1413 Cake\View\View::_render() - CORE/src/View/View.php, line 1374 Cake\View\View::renderLayout() - CORE/src/View/View.php, line 927 Cake\View\View::render() - CORE/src/View/View.php, line 885 Cake\Controller\Controller::render() - CORE/src/Controller/Controller.php, line 791 Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 126 Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94 Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96 Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65 Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51</pre></div></pre>latest-news-updates/pills-and-shills-15266.html"/> <meta http-equiv="Content-Type" content="text/html; charset=utf-8"/> <link href="https://im4change.in/css/control.css" rel="stylesheet" type="text/css" media="all"/> <title>LATEST NEWS UPDATES | Pills and shills | Im4change.org</title> <meta name="description" content=" -The Indian Express Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion..."/> <script src="https://im4change.in/js/jquery-1.10.2.js"></script> <script type="text/javascript" src="https://im4change.in/js/jquery-migrate.min.js"></script> <script language="javascript" type="text/javascript"> $(document).ready(function () { var img = $("img")[0]; // Get my img elem var pic_real_width, pic_real_height; $("<img/>") // Make in memory copy of image to avoid css issues .attr("src", $(img).attr("src")) .load(function () { pic_real_width = this.width; // Note: $(this).width() will not pic_real_height = this.height; // work for in memory images. }); }); </script> <style type="text/css"> @media screen { div.divFooter { display: block; } } @media print { .printbutton { display: none !important; } } </style> </head> <body> <table cellpadding="0" cellspacing="0" border="0" width="98%" align="center"> <tr> <td class="top_bg"> <div class="divFooter"> <img src="https://im4change.in/images/logo1.jpg" height="59" border="0" alt="Resource centre on India's rural distress" style="padding-top:14px;"/> </div> </td> </tr> <tr> <td id="topspace"> </td> </tr> <tr id="topspace"> <td> </td> </tr> <tr> <td height="50" style="border-bottom:1px solid #000; padding-top:10px;" class="printbutton"> <form><input type="button" value=" Print this page " onclick="window.print();return false;"/></form> </td> </tr> <tr> <td width="100%"> <h1 class="news_headlines" style="font-style:normal"> <strong>Pills and shills</strong></h1> </td> </tr> <tr> <td width="100%" style="font-family:Arial, 'Segoe Script', 'Segoe UI', sans-serif, serif"><font size="3"> <p>-The Indian Express</p><div align="justify"><em>Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame<br /></em><br />Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion between the regulator, industry and the medical profession that puts patients last. Over 118 pages, it said that the Drug Controller General of India (DCGI) and the Drug Standards Control Organisation (DSCO) have betrayed their regulatory responsibility in the manner in which they granted approvals. Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors’ opinions are irrelevant to the introduction of drugs in the Indian market.<br /><br />Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis’s Everolimus, Eli Lilly’s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a “public interest” escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. When expert opinion was consulted, it was seemingly dictated by what the report calls the “invisible hand” of pharma companies, sometimes the testimonials echoing each other word-for-word. In one case, with Thermis Medicare Ltd, the regulator asked the company to select its own experts, and bring their opinion to it. To be fair, there are reasons for this sloppiness — while the pharma industry is exploding, and the DSCO’s workload is growing by 20 per cent every year, it lacks the staff and infrastructure, advisers and independent testing labs to do its job. <br /><br />This is not a moment to blame each other. Doctors have been part of this corrupt edifice, along with companies and regulatory officials. Medicines, after all, are an area where consumers are not equipped to make informed decisions. They rely on those who know better to look out for their interests. And they have been sorely let down. <br /></div> </font> </td> </tr> <tr> <td> </td> </tr> <tr> <td height="50" style="border-top:1px solid #000; border-bottom:1px solid #000;padding-top:10px;"> <form><input type="button" value=" Print this page " onclick="window.print();return false;"/></form> </td> </tr> </table></body> </html>' } $cookies = [] $values = [ (int) 0 => 'text/html; charset=UTF-8' ] $name = 'Content-Type' $first = true $value = 'text/html; charset=UTF-8'header - [internal], line ?? Cake\Http\ResponseEmitter::emitHeaders() - CORE/src/Http/ResponseEmitter.php, line 181 Cake\Http\ResponseEmitter::emit() - CORE/src/Http/ResponseEmitter.php, line 55 Cake\Http\Server::emit() - CORE/src/Http/Server.php, line 141 [main] - ROOT/webroot/index.php, line 39
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Pills and shills |
-The Indian Express Drug regulation is a mess. Everyone who propped up this irresponsible system is to blame
Last week, a parliamentary standing committee on health delivered a thoroughly damaging report on the state of drug regulation in India, and the collusion between the regulator, industry and the medical profession that puts patients last. Over 118 pages, it said that the Drug Controller General of India (DCGI) and the Drug Standards Control Organisation (DSCO) have betrayed their regulatory responsibility in the manner in which they granted approvals. Now, several senior doctors, rebuked for letting their connections with pharmaceutical companies affect their drug endorsements, beg to differ. According to them, regulation is not their problem, and doctors’ opinions are irrelevant to the introduction of drugs in the Indian market. Except not. The committee found that many drugs were being marketed before they had been put through the required clinical trials (Novartis’s Everolimus, Eli Lilly’s Pemetexid, for instance), and several drugs banned in other markets were bought and sold here. The law mandates that any new drug introduced in India must be put through local Phase 3 clinical trials, on at least 100 people. Instead, using a “public interest” escape route, the DSCO had waived the clinical trial requirement without being able to back up its decisions. Regulatory dossiers were missing for several drugs, and in many cases, approvals were granted by non-technical staff. When expert opinion was consulted, it was seemingly dictated by what the report calls the “invisible hand” of pharma companies, sometimes the testimonials echoing each other word-for-word. In one case, with Thermis Medicare Ltd, the regulator asked the company to select its own experts, and bring their opinion to it. To be fair, there are reasons for this sloppiness — while the pharma industry is exploding, and the DSCO’s workload is growing by 20 per cent every year, it lacks the staff and infrastructure, advisers and independent testing labs to do its job. This is not a moment to blame each other. Doctors have been part of this corrupt edifice, along with companies and regulatory officials. Medicines, after all, are an area where consumers are not equipped to make informed decisions. They rely on those who know better to look out for their interests. And they have been sorely let down. |