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You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php. [CORE/src/Core/functions.php, line 311]
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Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51
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Deprecated (16384): The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 151
You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php. [CORE/src/Core/functions.php, line 311]
deprecationWarning - CORE/src/Core/functions.php, line 311
Cake\Http\ServerRequest::offsetGet() - CORE/src/Http/ServerRequest.php, line 2421
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Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94
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LATEST NEWS UPDATES | India's patent ruling on cancer may open door for cheaper HIV drugs </title>
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India's move to strip German drugmaker Bayer of its exclusive rights to a cancer drug has set a precedent that could extend to other treatments, including modern HIV/AIDS drugs, in a major blow to global pharmaceutical firms, experts say.
On Monday,..."/>
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India's move to strip German drugmaker Bayer of its exclusive rights to a cancer drug has set a precedent that could extend to other treatments, including modern HIV/AIDS drugs, in a major blow to global pharmaceutical firms, experts say.
On Monday,..." />
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<h1 class="cat-box-title">India's patent ruling on cancer may open door for cheaper HIV drugs</h1>
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<div style="text-align: justify"><br /></div><div style="text-align: justify">-Reuters</div><div style="text-align: justify"><br /></div><div style="text-align: justify">India's move to strip German drugmaker Bayer of its exclusive rights to a cancer drug has set a precedent that could extend to other treatments, including modern HIV/AIDS drugs, in a major blow to global pharmaceutical firms, experts say. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">On Monday, the Indian Patent Office effectively ended Bayer's monopoly for its Nexavar drug and issued its first-ever compulsory license allowing local generic maker Natco Pharma to make and sell the drug cheaply in India. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">It is only the second time a nation has issued a compulsory license for a cancer drug after Thailand did so on four drugs between 2006 and 2008, also on affordability grounds. Thailand also issued licenses for HIV/AIDS and heart disease treatments. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"This could well be the first of many compulsory rulings here," said Gopakumar G Nair, head of patent law firm Gopakumar Nair Associates and former president of the Indian Drug Manufacturers' Association. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"Global pharmaceutical manufacturers are likely to be worried as a result ... given that the wording in India's Patent Act that had been amended from 'reasonably priced' to 'reasonably affordable priced' has come into play now." </div><div style="text-align: justify"><br /></div><div style="text-align: justify">The new wording is seen as a lower threshold for compulsory licenses, which can be issued under world trade rules by nations that deem major life-saving drugs to be too costly. The licenses allow them to authorise the local manufacture or importation of much cheaper, generic versions. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Global drugmakers see emerging markets such as India as key growth opportunities, but remain concerned over intellectual property protection. Nair said HIV-related medicines were likely to be the most at risk by compulsory licenses in the future. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">India has one of the world's fastest-growing rates of HIV and heart disease is also the country's biggest killer, but widespread poverty in Asia's third-largest economy makes many non-generic drugs unaffordable for millions. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Currently, Pfizer and GlaxoSmithKline sell a modern HIV/AIDS drug known as Selzentry through their joint venture firm ViiV Healthcare. The treatment costs more than 60,000 rupees for one month's dosage in India. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Bayer's Nexavar cancer drug costs around $5,500 a month in India, making it "not available to the public at a reasonably affordable price", the patent office ruled. About 40 percent of Indians live below the poverty line, government data shows. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">A provision of the Indian Patents Act allows for a compulsory license to be awarded after three years of the grant of patent on drugs that are deemed to be too costly. </div><div style="text-align: justify"><br /></div><div style="text-align: justify"><em>MORE TO COME? </em></div><div style="text-align: justify"><br /></div><div style="text-align: justify">Other patent rulings are imminent. A long-running case involving the granting of an Indian patent for Swiss drugmaker Novartis' cancer drug Glivec is expected to be heard in the country's Supreme Court this month. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">The case does not involve the issue of compulsory license, but it has also pitted advocates of free trade and intellectual property rights against pro-generics campaigners who say a ruling in favour of Novartis could see other drugs in India priced outside of the reach of most of the population. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"This (Bayer) case might become a trend-setter, wherein generic players can make copies of patented products," said Siddhant Khandekar, analyst at ICICI Direct. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"While global giants might not like this, generic companies will benefit along with common people," he said, adding that the cancer treatment market in India was worth up to 30 billion rupees. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">The Bayer case underscores the still fractious relationship between global pharmaceutical firms and India. Companies like Pfizer, GlaxoSmithKline and Novartis are eyeing India and other emerging markets, notably China, as a growth opportunity but worry about property protection in a country that is also a leading source of cheap copycat medicines. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"Big Pharma" has recently struck some alliances with Indian drugmakers to tap into their generics expertise, but these have also not always run smoothly, with Pfizer on Tuesday scrapping a partnership with India's Biocon Ltd. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">In cancer treatments, India's Cipla Ltd, which has the second largest share of the local drugs market, may also benefit from the Bayer case. Cipla is fighting a Bayer suit for patent infringement after the Indian drugmaker launched a generic version of Nexavar in India in April 2010. </div><div style="text-align: justify"><br /></div><div style="text-align: justify"><em>BAYER CONSIDERS OPTIONS </em></div><div style="text-align: justify"><br /></div><div style="text-align: justify">Natco's finance chief, Baskara Narayana, told Reuters that sales of the generic version of Nexavar, whose chemical name is sorafenib, were expected to be about 250 million to 300 million rupees a year once it is launched. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Bayer, which developed Nexavar with US biotech firm Onyx Pharmaceuticals, said it was evaluating its options. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"We are disappointed by the decision of the Patent Controller in India to grant a compulsory license for Nexavar," Bayer said in a statement. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Tapan Ray, director general of the Organisation of Pharmaceutical Producers of India, an industry group of multi-national drugmakers, said the Bayer ruling was disappointing. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"The solution to helping patients with innovative medicines does not lie in breaking patents or denying patent rights to the innovators," Ray said. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Pfizer has questioned the issue of affordability, saying many Indians are well off and can afford Western medicines. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"There is huge wealth in India," Pfizer CEO Ian Read told Reuters in London on Monday. "There are maybe 100 million people in India who have wealth equivalent to or greater than the average European or American, who don't pay for innovation. So this is going to have to be a discussion at some point." </div><div style="text-align: justify"><br /></div><div style="text-align: justify">But groups that campaign for cheap access to drugs in poor countries have welcomed the Bayer ruling. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Medecins Sans Frontieres said the ruling means that new medicines in India that are still under patent, including some of the latest treatments for HIV/AIDS, could potentially have generic versions produced for a fraction of the cost. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"It's a bold move by the government and it's a good judgment ... which will benefit people," said Dara Patel, secretary general of the Indian Drug Manufacturers' Association, an industry body of Indian companies. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"Drugs to treat heart-related diseases and HIV are costly," said Patel. "Compulsory licensing will make them available at one-fourth or one-fifth of the price, which is good."</div><div style="text-align: justify"><br /></div>
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<br><a href="http://timesofindia.indiatimes.com/business/india-business/Indias-patent-ruling-on-cancer-may-open-door-for-cheaper-HIV-drugs/articleshow/12250451.cms" class="re" target="_blank">The Times of India, 13 March, 2012, http://timesofindia.indiatimes.com/business/india-business/Indias-patent-ruling-on-cancer-may-open-door-for-cheaper-HIV-drugs/articleshow/12250451.cms</a><div class="clear"></div>
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<h1 class="cat-box-title">India's patent ruling on cancer may open door for cheaper HIV drugs</h1>
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Published on</span><span class="text-date"> Mar 13, 2012</span>
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<div style="text-align: justify"><br /></div><div style="text-align: justify">-Reuters</div><div style="text-align: justify"><br /></div><div style="text-align: justify">India's move to strip German drugmaker Bayer of its exclusive rights to a cancer drug has set a precedent that could extend to other treatments, including modern HIV/AIDS drugs, in a major blow to global pharmaceutical firms, experts say. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">On Monday, the Indian Patent Office effectively ended Bayer's monopoly for its Nexavar drug and issued its first-ever compulsory license allowing local generic maker Natco Pharma to make and sell the drug cheaply in India. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">It is only the second time a nation has issued a compulsory license for a cancer drug after Thailand did so on four drugs between 2006 and 2008, also on affordability grounds. Thailand also issued licenses for HIV/AIDS and heart disease treatments. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"This could well be the first of many compulsory rulings here," said Gopakumar G Nair, head of patent law firm Gopakumar Nair Associates and former president of the Indian Drug Manufacturers' Association. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"Global pharmaceutical manufacturers are likely to be worried as a result ... given that the wording in India's Patent Act that had been amended from 'reasonably priced' to 'reasonably affordable priced' has come into play now." </div><div style="text-align: justify"><br /></div><div style="text-align: justify">The new wording is seen as a lower threshold for compulsory licenses, which can be issued under world trade rules by nations that deem major life-saving drugs to be too costly. The licenses allow them to authorise the local manufacture or importation of much cheaper, generic versions. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Global drugmakers see emerging markets such as India as key growth opportunities, but remain concerned over intellectual property protection. Nair said HIV-related medicines were likely to be the most at risk by compulsory licenses in the future. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">India has one of the world's fastest-growing rates of HIV and heart disease is also the country's biggest killer, but widespread poverty in Asia's third-largest economy makes many non-generic drugs unaffordable for millions. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Currently, Pfizer and GlaxoSmithKline sell a modern HIV/AIDS drug known as Selzentry through their joint venture firm ViiV Healthcare. The treatment costs more than 60,000 rupees for one month's dosage in India. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Bayer's Nexavar cancer drug costs around $5,500 a month in India, making it "not available to the public at a reasonably affordable price", the patent office ruled. About 40 percent of Indians live below the poverty line, government data shows. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">A provision of the Indian Patents Act allows for a compulsory license to be awarded after three years of the grant of patent on drugs that are deemed to be too costly. </div><div style="text-align: justify"><br /></div><div style="text-align: justify"><em>MORE TO COME? </em></div><div style="text-align: justify"><br /></div><div style="text-align: justify">Other patent rulings are imminent. A long-running case involving the granting of an Indian patent for Swiss drugmaker Novartis' cancer drug Glivec is expected to be heard in the country's Supreme Court this month. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">The case does not involve the issue of compulsory license, but it has also pitted advocates of free trade and intellectual property rights against pro-generics campaigners who say a ruling in favour of Novartis could see other drugs in India priced outside of the reach of most of the population. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"This (Bayer) case might become a trend-setter, wherein generic players can make copies of patented products," said Siddhant Khandekar, analyst at ICICI Direct. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"While global giants might not like this, generic companies will benefit along with common people," he said, adding that the cancer treatment market in India was worth up to 30 billion rupees. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">The Bayer case underscores the still fractious relationship between global pharmaceutical firms and India. Companies like Pfizer, GlaxoSmithKline and Novartis are eyeing India and other emerging markets, notably China, as a growth opportunity but worry about property protection in a country that is also a leading source of cheap copycat medicines. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"Big Pharma" has recently struck some alliances with Indian drugmakers to tap into their generics expertise, but these have also not always run smoothly, with Pfizer on Tuesday scrapping a partnership with India's Biocon Ltd. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">In cancer treatments, India's Cipla Ltd, which has the second largest share of the local drugs market, may also benefit from the Bayer case. Cipla is fighting a Bayer suit for patent infringement after the Indian drugmaker launched a generic version of Nexavar in India in April 2010. </div><div style="text-align: justify"><br /></div><div style="text-align: justify"><em>BAYER CONSIDERS OPTIONS </em></div><div style="text-align: justify"><br /></div><div style="text-align: justify">Natco's finance chief, Baskara Narayana, told Reuters that sales of the generic version of Nexavar, whose chemical name is sorafenib, were expected to be about 250 million to 300 million rupees a year once it is launched. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Bayer, which developed Nexavar with US biotech firm Onyx Pharmaceuticals, said it was evaluating its options. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"We are disappointed by the decision of the Patent Controller in India to grant a compulsory license for Nexavar," Bayer said in a statement. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Tapan Ray, director general of the Organisation of Pharmaceutical Producers of India, an industry group of multi-national drugmakers, said the Bayer ruling was disappointing. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"The solution to helping patients with innovative medicines does not lie in breaking patents or denying patent rights to the innovators," Ray said. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Pfizer has questioned the issue of affordability, saying many Indians are well off and can afford Western medicines. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"There is huge wealth in India," Pfizer CEO Ian Read told Reuters in London on Monday. "There are maybe 100 million people in India who have wealth equivalent to or greater than the average European or American, who don't pay for innovation. So this is going to have to be a discussion at some point." </div><div style="text-align: justify"><br /></div><div style="text-align: justify">But groups that campaign for cheap access to drugs in poor countries have welcomed the Bayer ruling. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Medecins Sans Frontieres said the ruling means that new medicines in India that are still under patent, including some of the latest treatments for HIV/AIDS, could potentially have generic versions produced for a fraction of the cost. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"It's a bold move by the government and it's a good judgment ... which will benefit people," said Dara Patel, secretary general of the Indian Drug Manufacturers' Association, an industry body of Indian companies. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"Drugs to treat heart-related diseases and HIV are costly," said Patel. "Compulsory licensing will make them available at one-fourth or one-fifth of the price, which is good."</div><div style="text-align: justify"><br /></div>
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<br><a href="http://timesofindia.indiatimes.com/business/india-business/Indias-patent-ruling-on-cancer-may-open-door-for-cheaper-HIV-drugs/articleshow/12250451.cms" class="re" target="_blank">The Times of India, 13 March, 2012, http://timesofindia.indiatimes.com/business/india-business/Indias-patent-ruling-on-cancer-may-open-door-for-cheaper-HIV-drugs/articleshow/12250451.cms</a><div class="clear"></div>
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-Reuters
India's move to strip German drugmaker Bayer of its exclusive rights to a cancer drug has set a precedent that could extend to other treatments, including modern HIV/AIDS drugs, in a major blow to global pharmaceutical firms, experts say.
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<h1 class="cat-box-title">India's patent ruling on cancer may open door for cheaper HIV drugs</h1>
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<div style="text-align: justify"><br /></div><div style="text-align: justify">-Reuters</div><div style="text-align: justify"><br /></div><div style="text-align: justify">India's move to strip German drugmaker Bayer of its exclusive rights to a cancer drug has set a precedent that could extend to other treatments, including modern HIV/AIDS drugs, in a major blow to global pharmaceutical firms, experts say. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">On Monday, the Indian Patent Office effectively ended Bayer's monopoly for its Nexavar drug and issued its first-ever compulsory license allowing local generic maker Natco Pharma to make and sell the drug cheaply in India. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">It is only the second time a nation has issued a compulsory license for a cancer drug after Thailand did so on four drugs between 2006 and 2008, also on affordability grounds. Thailand also issued licenses for HIV/AIDS and heart disease treatments. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"This could well be the first of many compulsory rulings here," said Gopakumar G Nair, head of patent law firm Gopakumar Nair Associates and former president of the Indian Drug Manufacturers' Association. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"Global pharmaceutical manufacturers are likely to be worried as a result ... given that the wording in India's Patent Act that had been amended from 'reasonably priced' to 'reasonably affordable priced' has come into play now." </div><div style="text-align: justify"><br /></div><div style="text-align: justify">The new wording is seen as a lower threshold for compulsory licenses, which can be issued under world trade rules by nations that deem major life-saving drugs to be too costly. The licenses allow them to authorise the local manufacture or importation of much cheaper, generic versions. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Global drugmakers see emerging markets such as India as key growth opportunities, but remain concerned over intellectual property protection. Nair said HIV-related medicines were likely to be the most at risk by compulsory licenses in the future. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">India has one of the world's fastest-growing rates of HIV and heart disease is also the country's biggest killer, but widespread poverty in Asia's third-largest economy makes many non-generic drugs unaffordable for millions. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Currently, Pfizer and GlaxoSmithKline sell a modern HIV/AIDS drug known as Selzentry through their joint venture firm ViiV Healthcare. The treatment costs more than 60,000 rupees for one month's dosage in India. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Bayer's Nexavar cancer drug costs around $5,500 a month in India, making it "not available to the public at a reasonably affordable price", the patent office ruled. About 40 percent of Indians live below the poverty line, government data shows. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">A provision of the Indian Patents Act allows for a compulsory license to be awarded after three years of the grant of patent on drugs that are deemed to be too costly. </div><div style="text-align: justify"><br /></div><div style="text-align: justify"><em>MORE TO COME? </em></div><div style="text-align: justify"><br /></div><div style="text-align: justify">Other patent rulings are imminent. A long-running case involving the granting of an Indian patent for Swiss drugmaker Novartis' cancer drug Glivec is expected to be heard in the country's Supreme Court this month. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">The case does not involve the issue of compulsory license, but it has also pitted advocates of free trade and intellectual property rights against pro-generics campaigners who say a ruling in favour of Novartis could see other drugs in India priced outside of the reach of most of the population. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"This (Bayer) case might become a trend-setter, wherein generic players can make copies of patented products," said Siddhant Khandekar, analyst at ICICI Direct. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"While global giants might not like this, generic companies will benefit along with common people," he said, adding that the cancer treatment market in India was worth up to 30 billion rupees. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">The Bayer case underscores the still fractious relationship between global pharmaceutical firms and India. Companies like Pfizer, GlaxoSmithKline and Novartis are eyeing India and other emerging markets, notably China, as a growth opportunity but worry about property protection in a country that is also a leading source of cheap copycat medicines. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"Big Pharma" has recently struck some alliances with Indian drugmakers to tap into their generics expertise, but these have also not always run smoothly, with Pfizer on Tuesday scrapping a partnership with India's Biocon Ltd. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">In cancer treatments, India's Cipla Ltd, which has the second largest share of the local drugs market, may also benefit from the Bayer case. Cipla is fighting a Bayer suit for patent infringement after the Indian drugmaker launched a generic version of Nexavar in India in April 2010. </div><div style="text-align: justify"><br /></div><div style="text-align: justify"><em>BAYER CONSIDERS OPTIONS </em></div><div style="text-align: justify"><br /></div><div style="text-align: justify">Natco's finance chief, Baskara Narayana, told Reuters that sales of the generic version of Nexavar, whose chemical name is sorafenib, were expected to be about 250 million to 300 million rupees a year once it is launched. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Bayer, which developed Nexavar with US biotech firm Onyx Pharmaceuticals, said it was evaluating its options. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"We are disappointed by the decision of the Patent Controller in India to grant a compulsory license for Nexavar," Bayer said in a statement. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Tapan Ray, director general of the Organisation of Pharmaceutical Producers of India, an industry group of multi-national drugmakers, said the Bayer ruling was disappointing. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"The solution to helping patients with innovative medicines does not lie in breaking patents or denying patent rights to the innovators," Ray said. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Pfizer has questioned the issue of affordability, saying many Indians are well off and can afford Western medicines. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"There is huge wealth in India," Pfizer CEO Ian Read told Reuters in London on Monday. "There are maybe 100 million people in India who have wealth equivalent to or greater than the average European or American, who don't pay for innovation. So this is going to have to be a discussion at some point." </div><div style="text-align: justify"><br /></div><div style="text-align: justify">But groups that campaign for cheap access to drugs in poor countries have welcomed the Bayer ruling. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">Medecins Sans Frontieres said the ruling means that new medicines in India that are still under patent, including some of the latest treatments for HIV/AIDS, could potentially have generic versions produced for a fraction of the cost. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"It's a bold move by the government and it's a good judgment ... which will benefit people," said Dara Patel, secretary general of the Indian Drug Manufacturers' Association, an industry body of Indian companies. </div><div style="text-align: justify"><br /></div><div style="text-align: justify">"Drugs to treat heart-related diseases and HIV are costly," said Patel. "Compulsory licensing will make them available at one-fourth or one-fifth of the price, which is good."</div><div style="text-align: justify"><br /></div>
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<br><a href="http://timesofindia.indiatimes.com/business/india-business/Indias-patent-ruling-on-cancer-may-open-door-for-cheaper-HIV-drugs/articleshow/12250451.cms" class="re" target="_blank">The Times of India, 13 March, 2012, http://timesofindia.indiatimes.com/business/india-business/Indias-patent-ruling-on-cancer-may-open-door-for-cheaper-HIV-drugs/articleshow/12250451.cms</a><div class="clear"></div>
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LATEST NEWS UPDATES | India's patent ruling on cancer may open door for cheaper HIV drugs
India's patent ruling on cancer may open door for cheaper HIV drugs
Published on Mar 13, 2012
Modified on Mar 13, 2012
-Reuters
India's move to strip German drugmaker Bayer of its exclusive rights to a cancer drug has set a precedent that could extend to other treatments, including modern HIV/AIDS drugs, in a major blow to global pharmaceutical firms, experts say.
On Monday, the Indian Patent Office effectively ended Bayer's monopoly for its Nexavar drug and issued its first-ever compulsory license allowing local generic maker Natco Pharma to make and sell the drug cheaply in India.
It is only the second time a nation has issued a compulsory license for a cancer drug after Thailand did so on four drugs between 2006 and 2008, also on affordability grounds. Thailand also issued licenses for HIV/AIDS and heart disease treatments.
"This could well be the first of many compulsory rulings here," said Gopakumar G Nair, head of patent law firm Gopakumar Nair Associates and former president of the Indian Drug Manufacturers' Association.
"Global pharmaceutical manufacturers are likely to be worried as a result ... given that the wording in India's Patent Act that had been amended from 'reasonably priced' to 'reasonably affordable priced' has come into play now."
The new wording is seen as a lower threshold for compulsory licenses, which can be issued under world trade rules by nations that deem major life-saving drugs to be too costly. The licenses allow them to authorise the local manufacture or importation of much cheaper, generic versions.
Global drugmakers see emerging markets such as India as key growth opportunities, but remain concerned over intellectual property protection. Nair said HIV-related medicines were likely to be the most at risk by compulsory licenses in the future.
India has one of the world's fastest-growing rates of HIV and heart disease is also the country's biggest killer, but widespread poverty in Asia's third-largest economy makes many non-generic drugs unaffordable for millions.
Currently, Pfizer and GlaxoSmithKline sell a modern HIV/AIDS drug known as Selzentry through their joint venture firm ViiV Healthcare. The treatment costs more than 60,000 rupees for one month's dosage in India.
Bayer's Nexavar cancer drug costs around $5,500 a month in India, making it "not available to the public at a reasonably affordable price", the patent office ruled. About 40 percent of Indians live below the poverty line, government data shows.
A provision of the Indian Patents Act allows for a compulsory license to be awarded after three years of the grant of patent on drugs that are deemed to be too costly.
MORE TO COME?
Other patent rulings are imminent. A long-running case involving the granting of an Indian patent for Swiss drugmaker Novartis' cancer drug Glivec is expected to be heard in the country's Supreme Court this month.
The case does not involve the issue of compulsory license, but it has also pitted advocates of free trade and intellectual property rights against pro-generics campaigners who say a ruling in favour of Novartis could see other drugs in India priced outside of the reach of most of the population.
"This (Bayer) case might become a trend-setter, wherein generic players can make copies of patented products," said Siddhant Khandekar, analyst at ICICI Direct.
"While global giants might not like this, generic companies will benefit along with common people," he said, adding that the cancer treatment market in India was worth up to 30 billion rupees.
The Bayer case underscores the still fractious relationship between global pharmaceutical firms and India. Companies like Pfizer, GlaxoSmithKline and Novartis are eyeing India and other emerging markets, notably China, as a growth opportunity but worry about property protection in a country that is also a leading source of cheap copycat medicines.
"Big Pharma" has recently struck some alliances with Indian drugmakers to tap into their generics expertise, but these have also not always run smoothly, with Pfizer on Tuesday scrapping a partnership with India's Biocon Ltd.
In cancer treatments, India's Cipla Ltd, which has the second largest share of the local drugs market, may also benefit from the Bayer case. Cipla is fighting a Bayer suit for patent infringement after the Indian drugmaker launched a generic version of Nexavar in India in April 2010.
BAYER CONSIDERS OPTIONS
Natco's finance chief, Baskara Narayana, told Reuters that sales of the generic version of Nexavar, whose chemical name is sorafenib, were expected to be about 250 million to 300 million rupees a year once it is launched.
Bayer, which developed Nexavar with US biotech firm Onyx Pharmaceuticals, said it was evaluating its options.
"We are disappointed by the decision of the Patent Controller in India to grant a compulsory license for Nexavar," Bayer said in a statement.
Tapan Ray, director general of the Organisation of Pharmaceutical Producers of India, an industry group of multi-national drugmakers, said the Bayer ruling was disappointing.
"The solution to helping patients with innovative medicines does not lie in breaking patents or denying patent rights to the innovators," Ray said.
Pfizer has questioned the issue of affordability, saying many Indians are well off and can afford Western medicines.
"There is huge wealth in India," Pfizer CEO Ian Read told Reuters in London on Monday. "There are maybe 100 million people in India who have wealth equivalent to or greater than the average European or American, who don't pay for innovation. So this is going to have to be a discussion at some point."
But groups that campaign for cheap access to drugs in poor countries have welcomed the Bayer ruling.
Medecins Sans Frontieres said the ruling means that new medicines in India that are still under patent, including some of the latest treatments for HIV/AIDS, could potentially have generic versions produced for a fraction of the cost.
"It's a bold move by the government and it's a good judgment ... which will benefit people," said Dara Patel, secretary general of the Indian Drug Manufacturers' Association, an industry body of Indian companies.
"Drugs to treat heart-related diseases and HIV are costly," said Patel. "Compulsory licensing will make them available at one-fourth or one-fifth of the price, which is good."
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