Deprecated (16384): The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 150
 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php. [CORE/src/Core/functions.php, line 311]
Code Context


        trigger_error($message, E_USER_DEPRECATED);

    }
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 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php.'
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deprecationWarning - CORE/src/Core/functions.php, line 311
Cake\Http\ServerRequest::offsetGet() - CORE/src/Http/ServerRequest.php, line 2421
App\Controller\ArtileDetailController::index() - APP/Controller/ArtileDetailController.php, line 150
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Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 120
Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94
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Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
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Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51
Cake\Http\Server::run() - CORE/src/Http/Server.php, line 98

Deprecated (16384): The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 151
 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php. [CORE/src/Core/functions.php, line 311]
Code Context


        trigger_error($message, E_USER_DEPRECATED);

    }
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 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php.'
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deprecationWarning - CORE/src/Core/functions.php, line 311
Cake\Http\ServerRequest::offsetGet() - CORE/src/Http/ServerRequest.php, line 2421
App\Controller\ArtileDetailController::index() - APP/Controller/ArtileDetailController.php, line 151
Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 610
Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 120
Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94
Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 97
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51
Cake\Http\Server::run() - CORE/src/Http/Server.php, line 98

Warning (512): Unable to emit headers. Headers sent in file=/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php line=853 [CORE/src/Http/ResponseEmitter.php, line 48]
Code Context
            if (Configure::read('debug')) {

                trigger_error($message, E_USER_WARNING);

            } else {
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As a new rapid diagnostic test, endorsed by the WHO, will finally help detect more people with DR-TB

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		 Published on</span><span class="text-date"> Mar 23, 2011</span>
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                            <div align="justify"><em>As a new rapid diagnostic test, endorsed by the WHO, will finally help detect more people with DR-TB<br /><br />DR-TB medicines are very expensive<br /><br />Need to improve access to DR-TB drugs<br /></em><br />As a new rapid diagnostic test, endorsed by the World Health Organisation (WHO), will finally help detect more people with drug-resistant tuberculosis (DR-TB), there was need to solve problems around the pricing and supply of DR-TB medicines, according to a report by international medical humanitarian organisation M&eacute;decins Sans Fronti&egrave;res (MSF).<br /><br />The DR-TB is on the rise, but less than 7 per cent of 4,40,000 new cases each year receive treatment. It kills 150,000 people in the world annually, according to the WHO. India is one of the countries with the highest burden of DR-TB cases in the world, with more than 99,000 new cases each year.<br /><br />The MSF report, released to mark World TB Day, shows that DR-TB drugs are riddled with persistent supply and price problems that must be urgently addressed.<br /><br />The report examines medicines used to treat DR-TB according to the number of suppliers, quality assurance and price, based on information obtained from the Global Drug Facility and drug manufacturers.<br /><br />The report highlights that four of the recommended DR-TB medicines are available from only one quality-assured generic source.<br /><br />Relying on a sole supplier whose production could be disrupted or stopped at any time always carries a risk of dangerous treatment interruption for patients. For example, supplies of injectable drug kanamycin were disrupted in 2010, leading to a temporary global stock out.<br /><br />&ldquo;In India and several other countries, resistance to TB drugs is a serious public health issue, which cannot be allowed to get worse,&rdquo; said Blessina Kumar of Stop TB Partnership.<br /><br />&ldquo;Patients have been stuck in a vicious circle &ndash; not enough people are diagnosed, and drug supply problems along with high prices stand in the way of putting more people on treatment.&rdquo;<br /><br />Additionally, the MSF report found that several DR-TB medicines are very expensive, with prices for two drugs having increased by more than 600 per cent and one drug by more than 800 per cent over the last decade.<br /><br />A 24-month DR-TB treatment regimen can cost as much as $9,000 for one patient &mdash; 470 times more than the $19 per patient it costs to cure standard, drug-sensitive TB.<br /><br />&ldquo;Now that we have a new test that can detect DR-TB in less than two hours instead of three months, we're going to see many more people who will need reliable drug supplies to get treated,&rdquo; said Joanna Ladomirska, Medical Coordinator for MSF in India.<br /><br />&ldquo;We need to see some immediate action to improve access to DR-TB drugs so that more people are started on treatment and transmission of this disease is reduced. This is particularly important in India, given the high burden of DR-TB here,&rdquo; said Ladomirska.<br /><br />The low demand for DR-TB drugs had made the market unattractive for producers, which was reinforcing the supply and price problems.<br /><br />One way to kick start increased production of some of these drugs is for donors to guarantee purchase volumes for several years to producers upfront.<br /><br />Other mechanisms such as better forecasting of the mid-to long-term needs for DR-TB drugs are also needed to help attract more producers to the market, to improve supply security and increase competition that helps brings prices down.<br /><br />&ldquo;With faster diagnosis and better treatment models of the DR-TB, we need to fix the supply and price issues with DR-TB drugs. We also need to see newer drugs developed,&rdquo; said Ladomirska.</div>                                                           
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    <br><a href="http://www.hindu.com/2011/03/24/stories/2011032455751500.htm" class="re" target="_blank">The Hindu, 24 March, 2011, http://www.hindu.com/2011/03/24/stories/2011032455751500.htm</a><div class="clear"></div>
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    <h1 class="cat-box-title">Need to maintain prices, supply of drug-resistant tuberculosis medicines: Médecins Sans Frontières by Aarti Dhar</h1>
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                            <div align="justify"><em>As a new rapid diagnostic test, endorsed by the WHO, will finally help detect more people with DR-TB<br /><br />DR-TB medicines are very expensive<br /><br />Need to improve access to DR-TB drugs<br /></em><br />As a new rapid diagnostic test, endorsed by the World Health Organisation (WHO), will finally help detect more people with drug-resistant tuberculosis (DR-TB), there was need to solve problems around the pricing and supply of DR-TB medicines, according to a report by international medical humanitarian organisation M&eacute;decins Sans Fronti&egrave;res (MSF).<br /><br />The DR-TB is on the rise, but less than 7 per cent of 4,40,000 new cases each year receive treatment. It kills 150,000 people in the world annually, according to the WHO. India is one of the countries with the highest burden of DR-TB cases in the world, with more than 99,000 new cases each year.<br /><br />The MSF report, released to mark World TB Day, shows that DR-TB drugs are riddled with persistent supply and price problems that must be urgently addressed.<br /><br />The report examines medicines used to treat DR-TB according to the number of suppliers, quality assurance and price, based on information obtained from the Global Drug Facility and drug manufacturers.<br /><br />The report highlights that four of the recommended DR-TB medicines are available from only one quality-assured generic source.<br /><br />Relying on a sole supplier whose production could be disrupted or stopped at any time always carries a risk of dangerous treatment interruption for patients. For example, supplies of injectable drug kanamycin were disrupted in 2010, leading to a temporary global stock out.<br /><br />&ldquo;In India and several other countries, resistance to TB drugs is a serious public health issue, which cannot be allowed to get worse,&rdquo; said Blessina Kumar of Stop TB Partnership.<br /><br />&ldquo;Patients have been stuck in a vicious circle &ndash; not enough people are diagnosed, and drug supply problems along with high prices stand in the way of putting more people on treatment.&rdquo;<br /><br />Additionally, the MSF report found that several DR-TB medicines are very expensive, with prices for two drugs having increased by more than 600 per cent and one drug by more than 800 per cent over the last decade.<br /><br />A 24-month DR-TB treatment regimen can cost as much as $9,000 for one patient &mdash; 470 times more than the $19 per patient it costs to cure standard, drug-sensitive TB.<br /><br />&ldquo;Now that we have a new test that can detect DR-TB in less than two hours instead of three months, we're going to see many more people who will need reliable drug supplies to get treated,&rdquo; said Joanna Ladomirska, Medical Coordinator for MSF in India.<br /><br />&ldquo;We need to see some immediate action to improve access to DR-TB drugs so that more people are started on treatment and transmission of this disease is reduced. This is particularly important in India, given the high burden of DR-TB here,&rdquo; said Ladomirska.<br /><br />The low demand for DR-TB drugs had made the market unattractive for producers, which was reinforcing the supply and price problems.<br /><br />One way to kick start increased production of some of these drugs is for donors to guarantee purchase volumes for several years to producers upfront.<br /><br />Other mechanisms such as better forecasting of the mid-to long-term needs for DR-TB drugs are also needed to help attract more producers to the market, to improve supply security and increase competition that helps brings prices down.<br /><br />&ldquo;With faster diagnosis and better treatment models of the DR-TB, we need to fix the supply and price issues with DR-TB drugs. We also need to see newer drugs developed,&rdquo; said Ladomirska.</div>                                                           
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    <br><a href="http://www.hindu.com/2011/03/24/stories/2011032455751500.htm" class="re" target="_blank">The Hindu, 24 March, 2011, http://www.hindu.com/2011/03/24/stories/2011032455751500.htm</a><div class="clear"></div>
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                            <div align="justify"><em>As a new rapid diagnostic test, endorsed by the WHO, will finally help detect more people with DR-TB<br /><br />DR-TB medicines are very expensive<br /><br />Need to improve access to DR-TB drugs<br /></em><br />As a new rapid diagnostic test, endorsed by the World Health Organisation (WHO), will finally help detect more people with drug-resistant tuberculosis (DR-TB), there was need to solve problems around the pricing and supply of DR-TB medicines, according to a report by international medical humanitarian organisation M&eacute;decins Sans Fronti&egrave;res (MSF).<br /><br />The DR-TB is on the rise, but less than 7 per cent of 4,40,000 new cases each year receive treatment. It kills 150,000 people in the world annually, according to the WHO. India is one of the countries with the highest burden of DR-TB cases in the world, with more than 99,000 new cases each year.<br /><br />The MSF report, released to mark World TB Day, shows that DR-TB drugs are riddled with persistent supply and price problems that must be urgently addressed.<br /><br />The report examines medicines used to treat DR-TB according to the number of suppliers, quality assurance and price, based on information obtained from the Global Drug Facility and drug manufacturers.<br /><br />The report highlights that four of the recommended DR-TB medicines are available from only one quality-assured generic source.<br /><br />Relying on a sole supplier whose production could be disrupted or stopped at any time always carries a risk of dangerous treatment interruption for patients. For example, supplies of injectable drug kanamycin were disrupted in 2010, leading to a temporary global stock out.<br /><br />&ldquo;In India and several other countries, resistance to TB drugs is a serious public health issue, which cannot be allowed to get worse,&rdquo; said Blessina Kumar of Stop TB Partnership.<br /><br />&ldquo;Patients have been stuck in a vicious circle &ndash; not enough people are diagnosed, and drug supply problems along with high prices stand in the way of putting more people on treatment.&rdquo;<br /><br />Additionally, the MSF report found that several DR-TB medicines are very expensive, with prices for two drugs having increased by more than 600 per cent and one drug by more than 800 per cent over the last decade.<br /><br />A 24-month DR-TB treatment regimen can cost as much as $9,000 for one patient &mdash; 470 times more than the $19 per patient it costs to cure standard, drug-sensitive TB.<br /><br />&ldquo;Now that we have a new test that can detect DR-TB in less than two hours instead of three months, we're going to see many more people who will need reliable drug supplies to get treated,&rdquo; said Joanna Ladomirska, Medical Coordinator for MSF in India.<br /><br />&ldquo;We need to see some immediate action to improve access to DR-TB drugs so that more people are started on treatment and transmission of this disease is reduced. This is particularly important in India, given the high burden of DR-TB here,&rdquo; said Ladomirska.<br /><br />The low demand for DR-TB drugs had made the market unattractive for producers, which was reinforcing the supply and price problems.<br /><br />One way to kick start increased production of some of these drugs is for donors to guarantee purchase volumes for several years to producers upfront.<br /><br />Other mechanisms such as better forecasting of the mid-to long-term needs for DR-TB drugs are also needed to help attract more producers to the market, to improve supply security and increase competition that helps brings prices down.<br /><br />&ldquo;With faster diagnosis and better treatment models of the DR-TB, we need to fix the supply and price issues with DR-TB drugs. We also need to see newer drugs developed,&rdquo; said Ladomirska.</div>                                                           
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Need to maintain prices, supply of drug-resistant tuberculosis medicines: Médecins Sans Frontières by Aarti Dhar

Published on Mar 23, 2011   Modified on Mar 23, 2011

As a new rapid diagnostic test, endorsed by the WHO, will finally help detect more people with DR-TB DR-TB medicines are very expensive Need to improve access to DR-TB drugs As a new rapid diagnostic test, endorsed by the World Health Organisation (WHO), will finally help detect more people with drug-resistant tuberculosis (DR-TB), there was need to solve problems around the pricing and supply of DR-TB medicines, according to a report by international medical humanitarian organisation Médecins Sans Frontières (MSF). The DR-TB is on the rise, but less than 7 per cent of 4,40,000 new cases each year receive treatment. It kills 150,000 people in the world annually, according to the WHO. India is one of the countries with the highest burden of DR-TB cases in the world, with more than 99,000 new cases each year. The MSF report, released to mark World TB Day, shows that DR-TB drugs are riddled with persistent supply and price problems that must be urgently addressed. The report examines medicines used to treat DR-TB according to the number of suppliers, quality assurance and price, based on information obtained from the Global Drug Facility and drug manufacturers. The report highlights that four of the recommended DR-TB medicines are available from only one quality-assured generic source. Relying on a sole supplier whose production could be disrupted or stopped at any time always carries a risk of dangerous treatment interruption for patients. For example, supplies of injectable drug kanamycin were disrupted in 2010, leading to a temporary global stock out. “In India and several other countries, resistance to TB drugs is a serious public health issue, which cannot be allowed to get worse,” said Blessina Kumar of Stop TB Partnership. “Patients have been stuck in a vicious circle – not enough people are diagnosed, and drug supply problems along with high prices stand in the way of putting more people on treatment.” Additionally, the MSF report found that several DR-TB medicines are very expensive, with prices for two drugs having increased by more than 600 per cent and one drug by more than 800 per cent over the last decade. A 24-month DR-TB treatment regimen can cost as much as $9,000 for one patient — 470 times more than the $19 per patient it costs to cure standard, drug-sensitive TB. “Now that we have a new test that can detect DR-TB in less than two hours instead of three months, we're going to see many more people who will need reliable drug supplies to get treated,” said Joanna Ladomirska, Medical Coordinator for MSF in India. “We need to see some immediate action to improve access to DR-TB drugs so that more people are started on treatment and transmission of this disease is reduced. This is particularly important in India, given the high burden of DR-TB here,” said Ladomirska. The low demand for DR-TB drugs had made the market unattractive for producers, which was reinforcing the supply and price problems. One way to kick start increased production of some of these drugs is for donors to guarantee purchase volumes for several years to producers upfront. Other mechanisms such as better forecasting of the mid-to long-term needs for DR-TB drugs are also needed to help attract more producers to the market, to improve supply security and increase competition that helps brings prices down. “With faster diagnosis and better treatment models of the DR-TB, we need to fix the supply and price issues with DR-TB drugs. We also need to see newer drugs developed,” said Ladomirska.

The Hindu, 24 March, 2011, http://www.hindu.com/2011/03/24/stories/2011032455751500.htm

Tagged with: Health

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