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LATEST NEWS UPDATES | New hepatitis cure far too costly -Martin Khor </title>
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A controversy is brewing over a new cure for hepatitis C because it is extremely expensive and patients in middle-income countries like Malaysia will find it way beyond their budget.
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A controversy is brewing over a new cure for hepatitis C because it is extremely expensive and patients in middle-income countries like Malaysia will find it way beyond their budget.
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<h1 class="cat-box-title">New hepatitis cure far too costly -Martin Khor</h1>
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Published on</span><span class="text-date"> Oct 13, 2014</span>
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<div align="justify">-Asia News Network</div><p align="justify">A controversy is brewing over a new cure for hepatitis C because it is extremely expensive and patients in middle-income countries like Malaysia will find it way beyond their budget.</p><p align="justify">There are an estimated 400,000 Malaysians with hepatitis C, but this is probably a significant under-estimate since many people are not aware that they have the virus.</p><p align="justify">Worldwide, 170 million people live with the hepatitis C virus (HCV), and every year three to four million more are infected, and there are around 350,000 deaths.</p><p align="justify">Hepatitis C is thus a major public health problem and called a "silent killer" because it can lead to serious liver ailments including cancer for those who are infected.</p><p align="justify">The good news is that a new drug, sofosbuvir, was approved last year by the American health authorities.</p><p align="justify">The medicine has an effective rate of around 90 per cent, making it superior to the older medicines which have a lower success rate and some serious side effects.</p><p align="justify">The bad news is that the producer, the US firm Gilead, put a very high price tag of US$84,000 for a 12-week course.</p><p align="justify">Each pill thus costs US$1,000.</p><p align="justify">The price could be set so high because the older and less effective alternatives cost about a third of that level, and the company also argued that a liver transplant (which the new medicine's cure would make unnecessary) would cost much higher.</p><p align="justify">Revenue from the new medicine since late last year has already run into many billions of dollars.</p><p align="justify">At that kind of price, only the very rich can afford the new medicine.</p><p align="justify">Patients in the West have difficulty even if they are insured, as the insurance companies or the National Health Service might not be able to put this expensive drug on their approved list.</p><p align="justify">There is now a wave of anger among health and patients' groups throughout the world.</p><p align="justify">Here is a life-saving medicine which is being priced out of reach, because the patents being filed by the company prevents competitors producing cheaper versions.</p><p align="justify">Opposition to a patent application was filed in India by a group, Initiative for Medicines, Access and Knowledge, on the ground that the drug made use of an existing compound.</p><p align="justify">In Indian law, patents need not be given for new uses of existing medicines or their compounds.</p><p align="justify">Facing mounting opposition, Gilead came up with a new initiative.</p><p align="justify">It made agreements with seven companies in India, allowing them to produce their own versions of sofosbuvir as well as another medicine, ledipasvir (which can be taken in combination), at prices these companies will set themselves.</p><p align="justify">A study at Liverpool University found that a full course of generic sofosbuvir could cost as low as US$101 and ledipasvir, US$93.</p><p align="justify">Another estimate is that the cost could be US$135-US$400.</p><p align="justify">Thus the Indian companies' prices are expected to be well below a thousand dollars.</p><p align="justify">An example from a decade ago is useful. When medicines for HIV-AIDS sold for US$15,000 a patient a year, Indian companies produced generic versions for US$350 a patient a year, and their prices fell further to about US$65 today.</p><p align="justify">There is, however, a major flaw in this new plan. While the agreements allow the Indian companies to sell the medicine in India and in some other countries, they are not allowed to market it in 51 middle-income developing countries.</p><p align="justify">Malaysia is one of these countries, together with 50 others including Thailand, the Philippines, China, Brazil and Argentina.</p><p align="justify">Patients and governments in these countries will thus be blocked from obtaining the cheap medicine coming from India.</p><p align="justify">The originator company plans to sell its brand in these excluded countries and thus reap high profits.</p><p align="justify">The price they charge may be less than US$84,000, but significantly higher than the Indian companies' prices.</p><p align="justify">The medical group, Medicins Sans Frontiers, has criticised this discrimination.</p><p align="justify">It said: "Hepatitis C is especially prevalent in middle-income countries, with approximately 73 per cent of the burden in these countries. But disappointingly many of these countries remain excluded from accessing Gilead's lowest price and the generic versions licensed by these agreements."</p><p align="justify">Patients in the excluded countries have expressed their anger.</p><p align="justify">In Malaysia, the Positive Malaysian Treatment Access and Advocacy Group and the Third World Network said the new oral medicines bring new hope for hepatitis C patients but these hopes were dashed by the restrictive terms of the agreements, thus "condemning to death many of the 50 million HCV patients living in territories excluded from the scope from the voluntary licence such as Malaysia, Thailand, Philippines and China".</p><p align="justify">Thirteen Thai NGOs issued a statement that they are appalled by the agreement that the originator signed with the Indian companies, which they said represented "corporate greed building yet another barrier to access to a new medicine needed by millions with hepatitis C infection in middle-income countries.</p><p align="justify">"In those middle-income countries not included in the deal, millions of people will be effectively handed a death sentence as the new life-saving medicine will be unaffordable."</p><p align="justify">The Brazilian Network for Integration of Peoples said it "vehemently repudiates the agreements which treat medicines as commodities, preventing millions of people to have access to medicines".</p><p align="justify">Patients in the affected countries, and their support groups, including the above, are calling on their governments to act to ensure that their citizens have access to the new medicines.</p><p align="justify">The countries are allowed by the WTO's intellectual property agreement not to grant patents if the medicines are not new or genuine inventions.</p><p align="justify">If patents have been granted, the governments can issue compulsory licences that allow generic companies or government firms to produce and sell generic medicines at cheap prices.</p><p align="justify">Alternatively, the governments can ask the company to include their countries to be among those that the Indian companies can supply to, or else that the prices charged by the company are the same as the cheapest generics.</p>
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<br><a href="http://www.asianewsnet.net/New-hepatitis-cure-far-too-costly-65764.html" class="re" target="_blank">The Star, 13 October, 2014, http://www.asianewsnet.net/New-hepatitis-cure-far-too-costly-65764.html</a><div class="clear"></div>
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<h1 class="cat-box-title">New hepatitis cure far too costly -Martin Khor</h1>
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Published on</span><span class="text-date"> Oct 13, 2014</span>
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<div align="justify">-Asia News Network</div><p align="justify">A controversy is brewing over a new cure for hepatitis C because it is extremely expensive and patients in middle-income countries like Malaysia will find it way beyond their budget.</p><p align="justify">There are an estimated 400,000 Malaysians with hepatitis C, but this is probably a significant under-estimate since many people are not aware that they have the virus.</p><p align="justify">Worldwide, 170 million people live with the hepatitis C virus (HCV), and every year three to four million more are infected, and there are around 350,000 deaths.</p><p align="justify">Hepatitis C is thus a major public health problem and called a "silent killer" because it can lead to serious liver ailments including cancer for those who are infected.</p><p align="justify">The good news is that a new drug, sofosbuvir, was approved last year by the American health authorities.</p><p align="justify">The medicine has an effective rate of around 90 per cent, making it superior to the older medicines which have a lower success rate and some serious side effects.</p><p align="justify">The bad news is that the producer, the US firm Gilead, put a very high price tag of US$84,000 for a 12-week course.</p><p align="justify">Each pill thus costs US$1,000.</p><p align="justify">The price could be set so high because the older and less effective alternatives cost about a third of that level, and the company also argued that a liver transplant (which the new medicine's cure would make unnecessary) would cost much higher.</p><p align="justify">Revenue from the new medicine since late last year has already run into many billions of dollars.</p><p align="justify">At that kind of price, only the very rich can afford the new medicine.</p><p align="justify">Patients in the West have difficulty even if they are insured, as the insurance companies or the National Health Service might not be able to put this expensive drug on their approved list.</p><p align="justify">There is now a wave of anger among health and patients' groups throughout the world.</p><p align="justify">Here is a life-saving medicine which is being priced out of reach, because the patents being filed by the company prevents competitors producing cheaper versions.</p><p align="justify">Opposition to a patent application was filed in India by a group, Initiative for Medicines, Access and Knowledge, on the ground that the drug made use of an existing compound.</p><p align="justify">In Indian law, patents need not be given for new uses of existing medicines or their compounds.</p><p align="justify">Facing mounting opposition, Gilead came up with a new initiative.</p><p align="justify">It made agreements with seven companies in India, allowing them to produce their own versions of sofosbuvir as well as another medicine, ledipasvir (which can be taken in combination), at prices these companies will set themselves.</p><p align="justify">A study at Liverpool University found that a full course of generic sofosbuvir could cost as low as US$101 and ledipasvir, US$93.</p><p align="justify">Another estimate is that the cost could be US$135-US$400.</p><p align="justify">Thus the Indian companies' prices are expected to be well below a thousand dollars.</p><p align="justify">An example from a decade ago is useful. When medicines for HIV-AIDS sold for US$15,000 a patient a year, Indian companies produced generic versions for US$350 a patient a year, and their prices fell further to about US$65 today.</p><p align="justify">There is, however, a major flaw in this new plan. While the agreements allow the Indian companies to sell the medicine in India and in some other countries, they are not allowed to market it in 51 middle-income developing countries.</p><p align="justify">Malaysia is one of these countries, together with 50 others including Thailand, the Philippines, China, Brazil and Argentina.</p><p align="justify">Patients and governments in these countries will thus be blocked from obtaining the cheap medicine coming from India.</p><p align="justify">The originator company plans to sell its brand in these excluded countries and thus reap high profits.</p><p align="justify">The price they charge may be less than US$84,000, but significantly higher than the Indian companies' prices.</p><p align="justify">The medical group, Medicins Sans Frontiers, has criticised this discrimination.</p><p align="justify">It said: "Hepatitis C is especially prevalent in middle-income countries, with approximately 73 per cent of the burden in these countries. But disappointingly many of these countries remain excluded from accessing Gilead's lowest price and the generic versions licensed by these agreements."</p><p align="justify">Patients in the excluded countries have expressed their anger.</p><p align="justify">In Malaysia, the Positive Malaysian Treatment Access and Advocacy Group and the Third World Network said the new oral medicines bring new hope for hepatitis C patients but these hopes were dashed by the restrictive terms of the agreements, thus "condemning to death many of the 50 million HCV patients living in territories excluded from the scope from the voluntary licence such as Malaysia, Thailand, Philippines and China".</p><p align="justify">Thirteen Thai NGOs issued a statement that they are appalled by the agreement that the originator signed with the Indian companies, which they said represented "corporate greed building yet another barrier to access to a new medicine needed by millions with hepatitis C infection in middle-income countries.</p><p align="justify">"In those middle-income countries not included in the deal, millions of people will be effectively handed a death sentence as the new life-saving medicine will be unaffordable."</p><p align="justify">The Brazilian Network for Integration of Peoples said it "vehemently repudiates the agreements which treat medicines as commodities, preventing millions of people to have access to medicines".</p><p align="justify">Patients in the affected countries, and their support groups, including the above, are calling on their governments to act to ensure that their citizens have access to the new medicines.</p><p align="justify">The countries are allowed by the WTO's intellectual property agreement not to grant patents if the medicines are not new or genuine inventions.</p><p align="justify">If patents have been granted, the governments can issue compulsory licences that allow generic companies or government firms to produce and sell generic medicines at cheap prices.</p><p align="justify">Alternatively, the governments can ask the company to include their countries to be among those that the Indian companies can supply to, or else that the prices charged by the company are the same as the cheapest generics.</p>
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<br><a href="http://www.asianewsnet.net/New-hepatitis-cure-far-too-costly-65764.html" class="re" target="_blank">The Star, 13 October, 2014, http://www.asianewsnet.net/New-hepatitis-cure-far-too-costly-65764.html</a><div class="clear"></div>
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A controversy is brewing over a new cure for hepatitis C because it is extremely expensive and patients in middle-income countries like Malaysia will find it way beyond their budget.
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<h1 class="cat-box-title">New hepatitis cure far too costly -Martin Khor</h1>
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Published on</span><span class="text-date"> Oct 13, 2014</span>
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<div align="justify">-Asia News Network</div><p align="justify">A controversy is brewing over a new cure for hepatitis C because it is extremely expensive and patients in middle-income countries like Malaysia will find it way beyond their budget.</p><p align="justify">There are an estimated 400,000 Malaysians with hepatitis C, but this is probably a significant under-estimate since many people are not aware that they have the virus.</p><p align="justify">Worldwide, 170 million people live with the hepatitis C virus (HCV), and every year three to four million more are infected, and there are around 350,000 deaths.</p><p align="justify">Hepatitis C is thus a major public health problem and called a "silent killer" because it can lead to serious liver ailments including cancer for those who are infected.</p><p align="justify">The good news is that a new drug, sofosbuvir, was approved last year by the American health authorities.</p><p align="justify">The medicine has an effective rate of around 90 per cent, making it superior to the older medicines which have a lower success rate and some serious side effects.</p><p align="justify">The bad news is that the producer, the US firm Gilead, put a very high price tag of US$84,000 for a 12-week course.</p><p align="justify">Each pill thus costs US$1,000.</p><p align="justify">The price could be set so high because the older and less effective alternatives cost about a third of that level, and the company also argued that a liver transplant (which the new medicine's cure would make unnecessary) would cost much higher.</p><p align="justify">Revenue from the new medicine since late last year has already run into many billions of dollars.</p><p align="justify">At that kind of price, only the very rich can afford the new medicine.</p><p align="justify">Patients in the West have difficulty even if they are insured, as the insurance companies or the National Health Service might not be able to put this expensive drug on their approved list.</p><p align="justify">There is now a wave of anger among health and patients' groups throughout the world.</p><p align="justify">Here is a life-saving medicine which is being priced out of reach, because the patents being filed by the company prevents competitors producing cheaper versions.</p><p align="justify">Opposition to a patent application was filed in India by a group, Initiative for Medicines, Access and Knowledge, on the ground that the drug made use of an existing compound.</p><p align="justify">In Indian law, patents need not be given for new uses of existing medicines or their compounds.</p><p align="justify">Facing mounting opposition, Gilead came up with a new initiative.</p><p align="justify">It made agreements with seven companies in India, allowing them to produce their own versions of sofosbuvir as well as another medicine, ledipasvir (which can be taken in combination), at prices these companies will set themselves.</p><p align="justify">A study at Liverpool University found that a full course of generic sofosbuvir could cost as low as US$101 and ledipasvir, US$93.</p><p align="justify">Another estimate is that the cost could be US$135-US$400.</p><p align="justify">Thus the Indian companies' prices are expected to be well below a thousand dollars.</p><p align="justify">An example from a decade ago is useful. When medicines for HIV-AIDS sold for US$15,000 a patient a year, Indian companies produced generic versions for US$350 a patient a year, and their prices fell further to about US$65 today.</p><p align="justify">There is, however, a major flaw in this new plan. While the agreements allow the Indian companies to sell the medicine in India and in some other countries, they are not allowed to market it in 51 middle-income developing countries.</p><p align="justify">Malaysia is one of these countries, together with 50 others including Thailand, the Philippines, China, Brazil and Argentina.</p><p align="justify">Patients and governments in these countries will thus be blocked from obtaining the cheap medicine coming from India.</p><p align="justify">The originator company plans to sell its brand in these excluded countries and thus reap high profits.</p><p align="justify">The price they charge may be less than US$84,000, but significantly higher than the Indian companies' prices.</p><p align="justify">The medical group, Medicins Sans Frontiers, has criticised this discrimination.</p><p align="justify">It said: "Hepatitis C is especially prevalent in middle-income countries, with approximately 73 per cent of the burden in these countries. But disappointingly many of these countries remain excluded from accessing Gilead's lowest price and the generic versions licensed by these agreements."</p><p align="justify">Patients in the excluded countries have expressed their anger.</p><p align="justify">In Malaysia, the Positive Malaysian Treatment Access and Advocacy Group and the Third World Network said the new oral medicines bring new hope for hepatitis C patients but these hopes were dashed by the restrictive terms of the agreements, thus "condemning to death many of the 50 million HCV patients living in territories excluded from the scope from the voluntary licence such as Malaysia, Thailand, Philippines and China".</p><p align="justify">Thirteen Thai NGOs issued a statement that they are appalled by the agreement that the originator signed with the Indian companies, which they said represented "corporate greed building yet another barrier to access to a new medicine needed by millions with hepatitis C infection in middle-income countries.</p><p align="justify">"In those middle-income countries not included in the deal, millions of people will be effectively handed a death sentence as the new life-saving medicine will be unaffordable."</p><p align="justify">The Brazilian Network for Integration of Peoples said it "vehemently repudiates the agreements which treat medicines as commodities, preventing millions of people to have access to medicines".</p><p align="justify">Patients in the affected countries, and their support groups, including the above, are calling on their governments to act to ensure that their citizens have access to the new medicines.</p><p align="justify">The countries are allowed by the WTO's intellectual property agreement not to grant patents if the medicines are not new or genuine inventions.</p><p align="justify">If patents have been granted, the governments can issue compulsory licences that allow generic companies or government firms to produce and sell generic medicines at cheap prices.</p><p align="justify">Alternatively, the governments can ask the company to include their countries to be among those that the Indian companies can supply to, or else that the prices charged by the company are the same as the cheapest generics.</p>
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<br><a href="http://www.asianewsnet.net/New-hepatitis-cure-far-too-costly-65764.html" class="re" target="_blank">The Star, 13 October, 2014, http://www.asianewsnet.net/New-hepatitis-cure-far-too-costly-65764.html</a><div class="clear"></div>
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LATEST NEWS UPDATES | New hepatitis cure far too costly -Martin Khor
Published on Oct 13, 2014
Modified on Oct 13, 2014
-Asia News Network
A controversy is brewing over a new cure for hepatitis C because it is extremely expensive and patients in middle-income countries like Malaysia will find it way beyond their budget.
There are an estimated 400,000 Malaysians with hepatitis C, but this is probably a significant under-estimate since many people are not aware that they have the virus.
Worldwide, 170 million people live with the hepatitis C virus (HCV), and every year three to four million more are infected, and there are around 350,000 deaths.
Hepatitis C is thus a major public health problem and called a "silent killer" because it can lead to serious liver ailments including cancer for those who are infected.
The good news is that a new drug, sofosbuvir, was approved last year by the American health authorities.
The medicine has an effective rate of around 90 per cent, making it superior to the older medicines which have a lower success rate and some serious side effects.
The bad news is that the producer, the US firm Gilead, put a very high price tag of US$84,000 for a 12-week course.
Each pill thus costs US$1,000.
The price could be set so high because the older and less effective alternatives cost about a third of that level, and the company also argued that a liver transplant (which the new medicine's cure would make unnecessary) would cost much higher.
Revenue from the new medicine since late last year has already run into many billions of dollars.
At that kind of price, only the very rich can afford the new medicine.
Patients in the West have difficulty even if they are insured, as the insurance companies or the National Health Service might not be able to put this expensive drug on their approved list.
There is now a wave of anger among health and patients' groups throughout the world.
Here is a life-saving medicine which is being priced out of reach, because the patents being filed by the company prevents competitors producing cheaper versions.
Opposition to a patent application was filed in India by a group, Initiative for Medicines, Access and Knowledge, on the ground that the drug made use of an existing compound.
In Indian law, patents need not be given for new uses of existing medicines or their compounds.
Facing mounting opposition, Gilead came up with a new initiative.
It made agreements with seven companies in India, allowing them to produce their own versions of sofosbuvir as well as another medicine, ledipasvir (which can be taken in combination), at prices these companies will set themselves.
A study at Liverpool University found that a full course of generic sofosbuvir could cost as low as US$101 and ledipasvir, US$93.
Another estimate is that the cost could be US$135-US$400.
Thus the Indian companies' prices are expected to be well below a thousand dollars.
An example from a decade ago is useful. When medicines for HIV-AIDS sold for US$15,000 a patient a year, Indian companies produced generic versions for US$350 a patient a year, and their prices fell further to about US$65 today.
There is, however, a major flaw in this new plan. While the agreements allow the Indian companies to sell the medicine in India and in some other countries, they are not allowed to market it in 51 middle-income developing countries.
Malaysia is one of these countries, together with 50 others including Thailand, the Philippines, China, Brazil and Argentina.
Patients and governments in these countries will thus be blocked from obtaining the cheap medicine coming from India.
The originator company plans to sell its brand in these excluded countries and thus reap high profits.
The price they charge may be less than US$84,000, but significantly higher than the Indian companies' prices.
The medical group, Medicins Sans Frontiers, has criticised this discrimination.
It said: "Hepatitis C is especially prevalent in middle-income countries, with approximately 73 per cent of the burden in these countries. But disappointingly many of these countries remain excluded from accessing Gilead's lowest price and the generic versions licensed by these agreements."
Patients in the excluded countries have expressed their anger.
In Malaysia, the Positive Malaysian Treatment Access and Advocacy Group and the Third World Network said the new oral medicines bring new hope for hepatitis C patients but these hopes were dashed by the restrictive terms of the agreements, thus "condemning to death many of the 50 million HCV patients living in territories excluded from the scope from the voluntary licence such as Malaysia, Thailand, Philippines and China".
Thirteen Thai NGOs issued a statement that they are appalled by the agreement that the originator signed with the Indian companies, which they said represented "corporate greed building yet another barrier to access to a new medicine needed by millions with hepatitis C infection in middle-income countries.
"In those middle-income countries not included in the deal, millions of people will be effectively handed a death sentence as the new life-saving medicine will be unaffordable."
The Brazilian Network for Integration of Peoples said it "vehemently repudiates the agreements which treat medicines as commodities, preventing millions of people to have access to medicines".
Patients in the affected countries, and their support groups, including the above, are calling on their governments to act to ensure that their citizens have access to the new medicines.
The countries are allowed by the WTO's intellectual property agreement not to grant patents if the medicines are not new or genuine inventions.
If patents have been granted, the governments can issue compulsory licences that allow generic companies or government firms to produce and sell generic medicines at cheap prices.
Alternatively, the governments can ask the company to include their countries to be among those that the Indian companies can supply to, or else that the prices charged by the company are the same as the cheapest generics.
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