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LATEST NEWS UPDATES | Tuberculosis breakthrough as scientists get funds for 'electronic nose' by Mark Tran </title>
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A mobile device that detects TB by 'sniffing' a person's breath will make a huge impact in villages far from health facilities
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A mobile device that detects TB by 'sniffing' a person's breath will make a huge impact in villages far from health facilities
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<h1 class="cat-box-title">Tuberculosis breakthrough as scientists get funds for 'electronic nose' by Mark Tran</h1>
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Published on</span><span class="text-date"> Nov 8, 2011</span>
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<div style="text-align: justify"><br /></div><div style="text-align: justify">A mobile device that detects TB by 'sniffing' a person's breath will make a huge impact in villages far from health facilities</div><div style="text-align: justify"><br /></div><div style="text-align: justify">A team of Indian researchers are planning to have a prototype of an "electronic nose" that can detect tuberculosis from a person's breath in hospitals by October 2013, after receiving a $950,000 grant on Monday.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">Working on the same principles as a breathalyser, the device – if successful – could mark a breakthrough in the fight against TB, which claimed 1.4 million lives last year and is second only to HIV and Aids as the world's most deadly infectious disease.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">One big advantage of this hand-held, battery powered device is that testing can be done at village level so people do not have to make the trip to distant hospitals or clinics for time-consuming testing with sputum.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">"At the moment, a person has to go to hospital at least twice, first for the test and then for the result," said Dr Ranjan Nanda, one of the lead researchers, from Delhi. "What we're preparing can go to the countryside in any temperature, any humidity, so a person doesn't have to travel and infect others on the way."</div><div style="text-align: justify"><br /></div><div style="text-align: justify">Nanda said the electronic nose will be able to diagnose TB by detecting changes in seven molecules, acting as a more sophisticated version of a breathalyser for suspected drink drivers.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">The researchers in India are working with sensors developed in California to track what are called biomarkers in the breath. Scientists say electronic noses could also be created for early detection of lung cancer and pneumonia, based on signature biomarkers of those diseases detectable in a patient's breath.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">Nanda and his team received a big vote of confidence with the grant from Grand Challenges Canada and the Bill & Melinda Gates foundation.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">"It's a bold idea with a potentially big impact developed by local innovators," said Dr Peter Singer, chief executive of Grand Challenges Canada, which works on health issues in the developing world. "It's a diagnostic life-saving device at the village level. Diagnosis is the weak link in the chain. With TB, if you don't diagnose someone in the village – that person will infect others and die."</div><div style="text-align: justify"><br /></div><div style="text-align: justify">It is estimated that up to 400,000 lives a year can be saved in the developing world by early diagnosis, immediate treatment and reduced transmission of TB. Like the common cold, TB is spread through the air. Only people who are sick with TB in their lungs are infectious.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">When infectious people cough, sneeze, talk or spit, they propel TB germs, known as bacilli, into the air. A person needs only to inhale a small number of these to be infected. Left untreated, each person with active TB will infect on average between 10 and 15 people every year.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">People infected with TB bacilli will not necessarily become sick with the disease. The immune system "walls off" the TB bacilli which, protected by a thick waxy coat, can lie dormant for years. When a person's immune system is weakened, the chances of becoming sick are greater.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">In its report last month, the World Health Organisation said for the first time the number of people falling ill with TB each year is declining. The WHO 2011 global tuberculosis control report showed that the number of people dying from the disease fell to its lowest level in a decade. However, current progress is at risk from underfunding, especially efforts to combat drug-resistant TB.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">The world and all of WHO's six regions are on track to achieve the millennium development goal target that TB incidence rates should be falling by 2015.</div><div style="text-align: justify"><br /></div>
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<br><a href="http://www.guardian.co.uk/global-development/2011/nov/07/tuberculosis-electronic-nose-device" class="re" target="_blank">The Guardian, 7 November, 2011, http://www.guardian.co.uk/global-development/2011/nov/07/tuberculosis-electronic-nose-device</a><div class="clear"></div>
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LATEST NEWS UPDATES | Tuberculosis breakthrough as scientists get funds for 'electronic nose' by Mark Tran </title>
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<h1 class="cat-box-title">Tuberculosis breakthrough as scientists get funds for 'electronic nose' by Mark Tran</h1>
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Published on</span><span class="text-date"> Nov 8, 2011</span>
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<div style="text-align: justify"><br /></div><div style="text-align: justify">A mobile device that detects TB by 'sniffing' a person's breath will make a huge impact in villages far from health facilities</div><div style="text-align: justify"><br /></div><div style="text-align: justify">A team of Indian researchers are planning to have a prototype of an "electronic nose" that can detect tuberculosis from a person's breath in hospitals by October 2013, after receiving a $950,000 grant on Monday.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">Working on the same principles as a breathalyser, the device – if successful – could mark a breakthrough in the fight against TB, which claimed 1.4 million lives last year and is second only to HIV and Aids as the world's most deadly infectious disease.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">One big advantage of this hand-held, battery powered device is that testing can be done at village level so people do not have to make the trip to distant hospitals or clinics for time-consuming testing with sputum.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">"At the moment, a person has to go to hospital at least twice, first for the test and then for the result," said Dr Ranjan Nanda, one of the lead researchers, from Delhi. "What we're preparing can go to the countryside in any temperature, any humidity, so a person doesn't have to travel and infect others on the way."</div><div style="text-align: justify"><br /></div><div style="text-align: justify">Nanda said the electronic nose will be able to diagnose TB by detecting changes in seven molecules, acting as a more sophisticated version of a breathalyser for suspected drink drivers.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">The researchers in India are working with sensors developed in California to track what are called biomarkers in the breath. Scientists say electronic noses could also be created for early detection of lung cancer and pneumonia, based on signature biomarkers of those diseases detectable in a patient's breath.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">Nanda and his team received a big vote of confidence with the grant from Grand Challenges Canada and the Bill & Melinda Gates foundation.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">"It's a bold idea with a potentially big impact developed by local innovators," said Dr Peter Singer, chief executive of Grand Challenges Canada, which works on health issues in the developing world. "It's a diagnostic life-saving device at the village level. Diagnosis is the weak link in the chain. With TB, if you don't diagnose someone in the village – that person will infect others and die."</div><div style="text-align: justify"><br /></div><div style="text-align: justify">It is estimated that up to 400,000 lives a year can be saved in the developing world by early diagnosis, immediate treatment and reduced transmission of TB. Like the common cold, TB is spread through the air. Only people who are sick with TB in their lungs are infectious.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">When infectious people cough, sneeze, talk or spit, they propel TB germs, known as bacilli, into the air. A person needs only to inhale a small number of these to be infected. Left untreated, each person with active TB will infect on average between 10 and 15 people every year.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">People infected with TB bacilli will not necessarily become sick with the disease. The immune system "walls off" the TB bacilli which, protected by a thick waxy coat, can lie dormant for years. When a person's immune system is weakened, the chances of becoming sick are greater.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">In its report last month, the World Health Organisation said for the first time the number of people falling ill with TB each year is declining. The WHO 2011 global tuberculosis control report showed that the number of people dying from the disease fell to its lowest level in a decade. However, current progress is at risk from underfunding, especially efforts to combat drug-resistant TB.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">The world and all of WHO's six regions are on track to achieve the millennium development goal target that TB incidence rates should be falling by 2015.</div><div style="text-align: justify"><br /></div>
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<br><a href="http://www.guardian.co.uk/global-development/2011/nov/07/tuberculosis-electronic-nose-device" class="re" target="_blank">The Guardian, 7 November, 2011, http://www.guardian.co.uk/global-development/2011/nov/07/tuberculosis-electronic-nose-device</a><div class="clear"></div>
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LATEST NEWS UPDATES | Tuberculosis breakthrough as scientists get funds for 'electronic nose' by Mark Tran </title>
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<h1 class="cat-box-title">Tuberculosis breakthrough as scientists get funds for 'electronic nose' by Mark Tran</h1>
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Published on</span><span class="text-date"> Nov 8, 2011</span>
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<div style="text-align: justify"><br /></div><div style="text-align: justify">A mobile device that detects TB by 'sniffing' a person's breath will make a huge impact in villages far from health facilities</div><div style="text-align: justify"><br /></div><div style="text-align: justify">A team of Indian researchers are planning to have a prototype of an "electronic nose" that can detect tuberculosis from a person's breath in hospitals by October 2013, after receiving a $950,000 grant on Monday.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">Working on the same principles as a breathalyser, the device – if successful – could mark a breakthrough in the fight against TB, which claimed 1.4 million lives last year and is second only to HIV and Aids as the world's most deadly infectious disease.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">One big advantage of this hand-held, battery powered device is that testing can be done at village level so people do not have to make the trip to distant hospitals or clinics for time-consuming testing with sputum.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">"At the moment, a person has to go to hospital at least twice, first for the test and then for the result," said Dr Ranjan Nanda, one of the lead researchers, from Delhi. "What we're preparing can go to the countryside in any temperature, any humidity, so a person doesn't have to travel and infect others on the way."</div><div style="text-align: justify"><br /></div><div style="text-align: justify">Nanda said the electronic nose will be able to diagnose TB by detecting changes in seven molecules, acting as a more sophisticated version of a breathalyser for suspected drink drivers.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">The researchers in India are working with sensors developed in California to track what are called biomarkers in the breath. Scientists say electronic noses could also be created for early detection of lung cancer and pneumonia, based on signature biomarkers of those diseases detectable in a patient's breath.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">Nanda and his team received a big vote of confidence with the grant from Grand Challenges Canada and the Bill & Melinda Gates foundation.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">"It's a bold idea with a potentially big impact developed by local innovators," said Dr Peter Singer, chief executive of Grand Challenges Canada, which works on health issues in the developing world. "It's a diagnostic life-saving device at the village level. Diagnosis is the weak link in the chain. With TB, if you don't diagnose someone in the village – that person will infect others and die."</div><div style="text-align: justify"><br /></div><div style="text-align: justify">It is estimated that up to 400,000 lives a year can be saved in the developing world by early diagnosis, immediate treatment and reduced transmission of TB. Like the common cold, TB is spread through the air. Only people who are sick with TB in their lungs are infectious.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">When infectious people cough, sneeze, talk or spit, they propel TB germs, known as bacilli, into the air. A person needs only to inhale a small number of these to be infected. Left untreated, each person with active TB will infect on average between 10 and 15 people every year.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">People infected with TB bacilli will not necessarily become sick with the disease. The immune system "walls off" the TB bacilli which, protected by a thick waxy coat, can lie dormant for years. When a person's immune system is weakened, the chances of becoming sick are greater.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">In its report last month, the World Health Organisation said for the first time the number of people falling ill with TB each year is declining. The WHO 2011 global tuberculosis control report showed that the number of people dying from the disease fell to its lowest level in a decade. However, current progress is at risk from underfunding, especially efforts to combat drug-resistant TB.</div><div style="text-align: justify"><br /></div><div style="text-align: justify">The world and all of WHO's six regions are on track to achieve the millennium development goal target that TB incidence rates should be falling by 2015.</div><div style="text-align: justify"><br /></div>
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<br><a href="http://www.guardian.co.uk/global-development/2011/nov/07/tuberculosis-electronic-nose-device" class="re" target="_blank">The Guardian, 7 November, 2011, http://www.guardian.co.uk/global-development/2011/nov/07/tuberculosis-electronic-nose-device</a><div class="clear"></div>
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LATEST NEWS UPDATES | Tuberculosis breakthrough as scientists get funds for 'electronic nose' by Mark Tran
Tuberculosis breakthrough as scientists get funds for 'electronic nose' by Mark Tran
Published on Nov 8, 2011
Modified on Nov 8, 2011
A mobile device that detects TB by 'sniffing' a person's breath will make a huge impact in villages far from health facilities
A team of Indian researchers are planning to have a prototype of an "electronic nose" that can detect tuberculosis from a person's breath in hospitals by October 2013, after receiving a $950,000 grant on Monday.
Working on the same principles as a breathalyser, the device – if successful – could mark a breakthrough in the fight against TB, which claimed 1.4 million lives last year and is second only to HIV and Aids as the world's most deadly infectious disease.
One big advantage of this hand-held, battery powered device is that testing can be done at village level so people do not have to make the trip to distant hospitals or clinics for time-consuming testing with sputum.
"At the moment, a person has to go to hospital at least twice, first for the test and then for the result," said Dr Ranjan Nanda, one of the lead researchers, from Delhi. "What we're preparing can go to the countryside in any temperature, any humidity, so a person doesn't have to travel and infect others on the way."
Nanda said the electronic nose will be able to diagnose TB by detecting changes in seven molecules, acting as a more sophisticated version of a breathalyser for suspected drink drivers.
The researchers in India are working with sensors developed in California to track what are called biomarkers in the breath. Scientists say electronic noses could also be created for early detection of lung cancer and pneumonia, based on signature biomarkers of those diseases detectable in a patient's breath.
Nanda and his team received a big vote of confidence with the grant from Grand Challenges Canada and the Bill & Melinda Gates foundation.
"It's a bold idea with a potentially big impact developed by local innovators," said Dr Peter Singer, chief executive of Grand Challenges Canada, which works on health issues in the developing world. "It's a diagnostic life-saving device at the village level. Diagnosis is the weak link in the chain. With TB, if you don't diagnose someone in the village – that person will infect others and die."
It is estimated that up to 400,000 lives a year can be saved in the developing world by early diagnosis, immediate treatment and reduced transmission of TB. Like the common cold, TB is spread through the air. Only people who are sick with TB in their lungs are infectious.
When infectious people cough, sneeze, talk or spit, they propel TB germs, known as bacilli, into the air. A person needs only to inhale a small number of these to be infected. Left untreated, each person with active TB will infect on average between 10 and 15 people every year.
People infected with TB bacilli will not necessarily become sick with the disease. The immune system "walls off" the TB bacilli which, protected by a thick waxy coat, can lie dormant for years. When a person's immune system is weakened, the chances of becoming sick are greater.
In its report last month, the World Health Organisation said for the first time the number of people falling ill with TB each year is declining. The WHO 2011 global tuberculosis control report showed that the number of people dying from the disease fell to its lowest level in a decade. However, current progress is at risk from underfunding, especially efforts to combat drug-resistant TB.
The world and all of WHO's six regions are on track to achieve the millennium development goal target that TB incidence rates should be falling by 2015.
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