Deprecated (16384): The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 150
 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php. [CORE/src/Core/functions.php, line 311]
Code Context


        trigger_error($message, E_USER_DEPRECATED);

    }
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 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php.'
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deprecationWarning - CORE/src/Core/functions.php, line 311
Cake\Http\ServerRequest::offsetGet() - CORE/src/Http/ServerRequest.php, line 2421
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Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51
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Deprecated (16384): The ArrayAccess methods will be removed in 4.0.0.Use getParam(), getData() and getQuery() instead. - /home/brlfuser/public_html/src/Controller/ArtileDetailController.php, line: 151
 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php. [CORE/src/Core/functions.php, line 311]
Code Context


        trigger_error($message, E_USER_DEPRECATED);

    }
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 You can disable deprecation warnings by setting `Error.errorLevel` to `E_ALL & ~E_USER_DEPRECATED` in your config/app.php.'
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deprecationWarning - CORE/src/Core/functions.php, line 311
Cake\Http\ServerRequest::offsetGet() - CORE/src/Http/ServerRequest.php, line 2421
App\Controller\ArtileDetailController::index() - APP/Controller/ArtileDetailController.php, line 151
Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 610
Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 120
Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94
Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 162
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 97
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Error\Middleware\ErrorHandlerMiddleware::__invoke() - CORE/src/Error/Middleware/ErrorHandlerMiddleware.php, line 96
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51
Cake\Http\Server::run() - CORE/src/Http/Server.php, line 98

Warning (512): Unable to emit headers. Headers sent in file=/home/brlfuser/public_html/vendor/cakephp/cakephp/src/Error/Debugger.php line=853 [CORE/src/Http/ResponseEmitter.php, line 48]
Code Context
            if (Configure::read('debug')) {

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        LATEST NEWS UPDATES | Tuberculosis of brain, spine on rise -Chetana Belagere    </title>
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Whole Genome Sequencing can detect cases; extra-pulmonary forms increasing in kids

BENGALURU: Multi Drug Resistant (MDR) TB continues to be on the rise. In many cases, this is leading to tuberculosis of the brain and spine. Experts working..."/>
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Whole Genome Sequencing can detect cases; extra-pulmonary forms increasing in kids

BENGALURU: Multi Drug Resistant (MDR) TB continues to be on the rise. In many cases, this is leading to tuberculosis of the brain and spine. Experts working..." />
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                            <p style="text-align:justify">-The New Indian Express</p><p style="text-align:justify"><em>Whole Genome Sequencing can detect cases; extra-pulmonary forms increasing in kids</em></p><p style="text-align:justify"><em>BENGALURU: </em>Multi Drug Resistant (MDR) TB continues to be on the rise. In many cases, this is leading to tuberculosis of the brain and spine. Experts working in the control room of TB burden in the state, say this area is overlooked and undiagnosed.&nbsp;</p><p style="text-align:justify">&ldquo;Extra-pulmonary manifestations of Tuberculosis are on the rise, with Tuberculosis of brain and spine cases increasing. TB mainly affects the lungs, which is called pulmonary tuberculosis, but if it affects other organs such as brain, spine, uterus, heart, skin etc, it is known as extra-pulmonary TB. These cases are on the rise,&rdquo; said Dr Sachet Dawar, Assistant Professor, Dept. of Respiratory Medicine, Noida International Institute of Medical Sciences.</p><p style="text-align:justify">In case of TB of the brain, the bacilli enters the blood vessels when someone with TB sneezes or coughs, and then go into the brain, causing inflammation of the Central Nervous System, causing meningitis. With TB meningitis, the person can have symptoms of repeated fever and headaches and also in later stages, go into confusions and coma. Similarly, the TB bacilli enters the spinal area of the body, leading to TB of the spine -- Pott&rsquo;s Disease symptoms of severe backache and degeneration of bones.</p><p style="text-align:justify">However, doctors claim the world is effectively treating drug-susceptible forms of TB, and if it doesn&rsquo;t, community transmission of drug-resistant forms of TB can snowball into a difficult-to-treat endemic.<br />Stressing on diagnosis, pulmonary experts say the available tests are not enough.</p><p style="text-align:justify">They are now calling for a wider rollout of ultra-sensitive tests to get conclusive results, as well as the use of newer specimens such as stool samples, which could also be easier to detect paediatric cases. They also cite the need for whole genome sequencing (WGS) on a large scale, to detect MDR TB cases. &ldquo;Though a battery of common Multi Drug Resistant TB tests is available, these tests fail to detect it,&rdquo; said a senior health department official. WGS, doctors claim, can emerge as the revolutionary one-stop solution for diagnosis and treatment of TB in India.&nbsp;</p><p style="text-align:justify">Please <a href="https://www.newindianexpress.com/cities/bengaluru/2022/mar/24/tuberculosis-of-brain-spine-on-rise-2433517.html?fbclid=IwAR3FkfDc2Fp7Y-prVdx1HOjyFe5YxCPIbUSAtg9RWQ0ZnGLkJuI5LrbOcp0" title="https://www.newindianexpress.com/cities/bengaluru/2022/mar/24/tuberculosis-of-brain-spine-on-rise-2433517.html?fbclid=IwAR3FkfDc2Fp7Y-prVdx1HOjyFe5YxCPIbUSAtg9RWQ0ZnGLkJuI5LrbOcp0">click here</a> to read more.&nbsp;</p>                                                           
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    <br><a href="https://www.newindianexpress.com/cities/bengaluru/2022/mar/24/tuberculosis-of-brain-spine-on-rise-2433517.html?fbclid=IwAR3FkfDc2Fp7Y-prVdx1HOjyFe5YxCPIbUSAtg9RWQ0ZnGLkJuI5LrbOcp0" class="re" target="_blank">The New Indian Express, 24 March, 2022, https://www.newindianexpress.com/cities/bengaluru/2022/mar/24/tuberculosis-of-brain-spine-on-rise-2433517.html?fbclid=IwAR3FkfDc2Fp7Y-prVdx1HOjyFe5YxCPIbUSAtg9RWQ0ZnGLkJuI5LrbOcp0</a><div class="clear"></div>
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                            <p style="text-align:justify">-The New Indian Express</p><p style="text-align:justify"><em>Whole Genome Sequencing can detect cases; extra-pulmonary forms increasing in kids</em></p><p style="text-align:justify"><em>BENGALURU: </em>Multi Drug Resistant (MDR) TB continues to be on the rise. In many cases, this is leading to tuberculosis of the brain and spine. Experts working in the control room of TB burden in the state, say this area is overlooked and undiagnosed.&nbsp;</p><p style="text-align:justify">&ldquo;Extra-pulmonary manifestations of Tuberculosis are on the rise, with Tuberculosis of brain and spine cases increasing. TB mainly affects the lungs, which is called pulmonary tuberculosis, but if it affects other organs such as brain, spine, uterus, heart, skin etc, it is known as extra-pulmonary TB. These cases are on the rise,&rdquo; said Dr Sachet Dawar, Assistant Professor, Dept. of Respiratory Medicine, Noida International Institute of Medical Sciences.</p><p style="text-align:justify">In case of TB of the brain, the bacilli enters the blood vessels when someone with TB sneezes or coughs, and then go into the brain, causing inflammation of the Central Nervous System, causing meningitis. With TB meningitis, the person can have symptoms of repeated fever and headaches and also in later stages, go into confusions and coma. Similarly, the TB bacilli enters the spinal area of the body, leading to TB of the spine -- Pott&rsquo;s Disease symptoms of severe backache and degeneration of bones.</p><p style="text-align:justify">However, doctors claim the world is effectively treating drug-susceptible forms of TB, and if it doesn&rsquo;t, community transmission of drug-resistant forms of TB can snowball into a difficult-to-treat endemic.<br />Stressing on diagnosis, pulmonary experts say the available tests are not enough.</p><p style="text-align:justify">They are now calling for a wider rollout of ultra-sensitive tests to get conclusive results, as well as the use of newer specimens such as stool samples, which could also be easier to detect paediatric cases. They also cite the need for whole genome sequencing (WGS) on a large scale, to detect MDR TB cases. &ldquo;Though a battery of common Multi Drug Resistant TB tests is available, these tests fail to detect it,&rdquo; said a senior health department official. WGS, doctors claim, can emerge as the revolutionary one-stop solution for diagnosis and treatment of TB in India.&nbsp;</p><p style="text-align:justify">Please <a href="https://www.newindianexpress.com/cities/bengaluru/2022/mar/24/tuberculosis-of-brain-spine-on-rise-2433517.html?fbclid=IwAR3FkfDc2Fp7Y-prVdx1HOjyFe5YxCPIbUSAtg9RWQ0ZnGLkJuI5LrbOcp0" title="https://www.newindianexpress.com/cities/bengaluru/2022/mar/24/tuberculosis-of-brain-spine-on-rise-2433517.html?fbclid=IwAR3FkfDc2Fp7Y-prVdx1HOjyFe5YxCPIbUSAtg9RWQ0ZnGLkJuI5LrbOcp0">click here</a> to read more.&nbsp;</p>                                                           
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    <br><a href="https://www.newindianexpress.com/cities/bengaluru/2022/mar/24/tuberculosis-of-brain-spine-on-rise-2433517.html?fbclid=IwAR3FkfDc2Fp7Y-prVdx1HOjyFe5YxCPIbUSAtg9RWQ0ZnGLkJuI5LrbOcp0" class="re" target="_blank">The New Indian Express, 24 March, 2022, https://www.newindianexpress.com/cities/bengaluru/2022/mar/24/tuberculosis-of-brain-spine-on-rise-2433517.html?fbclid=IwAR3FkfDc2Fp7Y-prVdx1HOjyFe5YxCPIbUSAtg9RWQ0ZnGLkJuI5LrbOcp0</a><div class="clear"></div>
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Whole Genome Sequencing can detect cases; extra-pulmonary forms increasing in kids

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                            <p style="text-align:justify">-The New Indian Express</p><p style="text-align:justify"><em>Whole Genome Sequencing can detect cases; extra-pulmonary forms increasing in kids</em></p><p style="text-align:justify"><em>BENGALURU: </em>Multi Drug Resistant (MDR) TB continues to be on the rise. In many cases, this is leading to tuberculosis of the brain and spine. Experts working in the control room of TB burden in the state, say this area is overlooked and undiagnosed.&nbsp;</p><p style="text-align:justify">&ldquo;Extra-pulmonary manifestations of Tuberculosis are on the rise, with Tuberculosis of brain and spine cases increasing. TB mainly affects the lungs, which is called pulmonary tuberculosis, but if it affects other organs such as brain, spine, uterus, heart, skin etc, it is known as extra-pulmonary TB. These cases are on the rise,&rdquo; said Dr Sachet Dawar, Assistant Professor, Dept. of Respiratory Medicine, Noida International Institute of Medical Sciences.</p><p style="text-align:justify">In case of TB of the brain, the bacilli enters the blood vessels when someone with TB sneezes or coughs, and then go into the brain, causing inflammation of the Central Nervous System, causing meningitis. With TB meningitis, the person can have symptoms of repeated fever and headaches and also in later stages, go into confusions and coma. Similarly, the TB bacilli enters the spinal area of the body, leading to TB of the spine -- Pott&rsquo;s Disease symptoms of severe backache and degeneration of bones.</p><p style="text-align:justify">However, doctors claim the world is effectively treating drug-susceptible forms of TB, and if it doesn&rsquo;t, community transmission of drug-resistant forms of TB can snowball into a difficult-to-treat endemic.<br />Stressing on diagnosis, pulmonary experts say the available tests are not enough.</p><p style="text-align:justify">They are now calling for a wider rollout of ultra-sensitive tests to get conclusive results, as well as the use of newer specimens such as stool samples, which could also be easier to detect paediatric cases. They also cite the need for whole genome sequencing (WGS) on a large scale, to detect MDR TB cases. &ldquo;Though a battery of common Multi Drug Resistant TB tests is available, these tests fail to detect it,&rdquo; said a senior health department official. WGS, doctors claim, can emerge as the revolutionary one-stop solution for diagnosis and treatment of TB in India.&nbsp;</p><p style="text-align:justify">Please <a href="https://www.newindianexpress.com/cities/bengaluru/2022/mar/24/tuberculosis-of-brain-spine-on-rise-2433517.html?fbclid=IwAR3FkfDc2Fp7Y-prVdx1HOjyFe5YxCPIbUSAtg9RWQ0ZnGLkJuI5LrbOcp0" title="https://www.newindianexpress.com/cities/bengaluru/2022/mar/24/tuberculosis-of-brain-spine-on-rise-2433517.html?fbclid=IwAR3FkfDc2Fp7Y-prVdx1HOjyFe5YxCPIbUSAtg9RWQ0ZnGLkJuI5LrbOcp0">click here</a> to read more.&nbsp;</p>                                                           
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Tuberculosis of brain, spine on rise -Chetana Belagere

Published on Mar 24, 2022   Modified on Mar 25, 2022

-The New Indian Express Whole Genome Sequencing can detect cases; extra-pulmonary forms increasing in kids BENGALURU: Multi Drug Resistant (MDR) TB continues to be on the rise. In many cases, this is leading to tuberculosis of the brain and spine. Experts working in the control room of TB burden in the state, say this area is overlooked and undiagnosed.  “Extra-pulmonary manifestations of Tuberculosis are on the rise, with Tuberculosis of brain and spine cases increasing. TB mainly affects the lungs, which is called pulmonary tuberculosis, but if it affects other organs such as brain, spine, uterus, heart, skin etc, it is known as extra-pulmonary TB. These cases are on the rise,” said Dr Sachet Dawar, Assistant Professor, Dept. of Respiratory Medicine, Noida International Institute of Medical Sciences. In case of TB of the brain, the bacilli enters the blood vessels when someone with TB sneezes or coughs, and then go into the brain, causing inflammation of the Central Nervous System, causing meningitis. With TB meningitis, the person can have symptoms of repeated fever and headaches and also in later stages, go into confusions and coma. Similarly, the TB bacilli enters the spinal area of the body, leading to TB of the spine -- Pott’s Disease symptoms of severe backache and degeneration of bones. However, doctors claim the world is effectively treating drug-susceptible forms of TB, and if it doesn’t, community transmission of drug-resistant forms of TB can snowball into a difficult-to-treat endemic. Stressing on diagnosis, pulmonary experts say the available tests are not enough. They are now calling for a wider rollout of ultra-sensitive tests to get conclusive results, as well as the use of newer specimens such as stool samples, which could also be easier to detect paediatric cases. They also cite the need for whole genome sequencing (WGS) on a large scale, to detect MDR TB cases. “Though a battery of common Multi Drug Resistant TB tests is available, these tests fail to detect it,” said a senior health department official. WGS, doctors claim, can emerge as the revolutionary one-stop solution for diagnosis and treatment of TB in India.  Please click here to read more.

The New Indian Express, 24 March, 2022, https://www.newindianexpress.com/cities/bengaluru/2022/mar/24/tuberculosis-of-brain-spine-on-rise-2433517.html?fbclid=IwAR3FkfDc2Fp7Y-prVdx1HOjyFe5YxCPIbUSAtg9RWQ0ZnGLkJuI5LrbOcp0

Tagged with: Tuberculosis Multi Drug Resistant Tuberculosis MDR TB Whole Genome Sequencing TB burden

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