Why has the incidence of tuberculosis in India remained around 170 per 100,000 people for the last 20 years despite DOTS, the directly observed treatment strategy, being in place? Answer: DOTS is a passive system that kicks in only after a person takes the initiative and gets tested for the disease. Despite the high prevalence and mortality rate, researchers are yet to figure out a system that works proactively, identifying...

Tuberculosis continues to be a major health problem in India. But the unveiling of a new test to diagnose TB and drug resistance on World Tuberculosis Day (March 24) brings some hope into a bleak scenario. Last Thursday, on World Tuberculosis Day, for the first time since the 1880s there was probably some justifiable cause for jubilation. After centuries of grappling with sputum smear microscopy, developed way back in the 1880s,...

When we hear the word innovation, we often think of new technologies or silver bullet solutions — like hydrogen fuel cells or a cure for cancer. To be sure, breakthroughs are vital: antibiotics and vaccines, for example, transformed global health. But as we’ve argued in Fixes, some of the greatest advances come from taking old ideas or technologies and making them accessible to millions of people who are underserved. One area...

Some Bhopal gas leak victims who survived the tragedy were used by Bhopal Memorial Hospital and Research Centre (BMHRC) for four years to carry out drug trails. The number of such people who were subjected to drug trials is 151. Ramadhar Shrivastva is one such gas victim. In 2007 when he had chest pain, he was referred to BMHRC, the multi-specialty hospital set up for gas victims from the money given...

India has played a crucial role in making essential medicines available and affordable for patients in the developing world through generic drugs. This has been possible by linking India’s patent policies and laws to public interest. Similarly, policies that align public funded R&D in India with public health have the potential to provide incentives to the development of medical technologies (vaccines, diagnostics and medicines) crucial for treating neglected diseases like...