-The Hindu Vaccine’s overall efficacy in a recent trial is ‘lower than expected’ The just concluded Phase IIb (proof-of-concept) dengue vaccine trial against all the four virus types (serotypes) that cause dengue has not only shown an unexpectedly low efficacy of 30.2 per cent but has also challenged many well-established hypotheses and ideas. The trial was conducted in about 4,000 children in the age group 4 and 11 in the dengue endemic district...

-The Hindu Tuberculosis (TB) has remained a major infectious disease in developing and poor countries despite all efforts from health agencies to manage and control it. In fact, even an easy and effective way to diagnose the disease has remained a challenge. Emergence of drug resistant strains has made its management more complex. The steps It makes the situation in countries like India, with the highest TB burden in the world, even more...

The debate about essential-medicine pricing and access in India illustrates the difficulties inherent in establishing policies that serve conflicting public interests in achieving goals such as caring well and ensuring safety for all, while also pursuing financially-sustainable success in scientific innovation and trade. It highlights problems facing those interested in continuing drug and vaccines development and ensuring that, once marketed, such products contribute effectively to improving public health. Modern pharmaceuticals...

Ignoring widespread concern over the safety, efficacy and cost of pentavalent vaccines, India’s central health ministry has, this month, approved inclusion of the prophylactic cocktail in the universal immunisation programme in seven of its provinces. Pentavalent vaccine doses, a cocktail of five antigens in a single shot, confers immunity against five paediatric diseases - diphtheria, pertussis, tetanus, hepatitis B and haemophilus influenza type b (Hib), with the last one considered particularly...

Each time 25 year old Salma takes her one year old son Zubair to the Batla Clinic (a private clinic in Delhi) for a shot of the DPT, the cost of transportation and the vaccine adds up to approximately Rs.500.   When it is time for Zubair to take the next immunization dose, Salma may find that the expenses have entirely spiraled out of her reach. New vaccines and expensive brands of baby...