India recorded 98,621 rotavirus-inducted diarrhoea deaths in 2008, which is about 22% of global toll from the infection.  Nigeria - the second worst-hit country - recorded about 41,000 deaths, or less than 50% of fatalities as compared to India.  Pakistan (39,000) and Bangladesh (9,000) figures among the top 10 worst-affected nations grappling with rotavirus infection, says a study that appeared in medical journal, "The Lancet Infectious Diseases". It shows 453,000 deaths occurred...

In a major breakthrough Tuesday, researchers announced that the vaccine candidate RTS,S reduces the risk of malaria by half in children ages five to 17 months, first results from a continuing phase three trial showed. The results have tremendous implications, as malaria is responsible for nearly 800,000 deaths annually. The disease kills one child every 45 seconds in Africa, where it accounts for approximately 20 percent of childhood deaths, according to...

The Union health ministry today banned the manufacture and sale of a drug called letrozole to treat infertility in women, four years after its own drug regulators had waived safety studies and relaxed rules to approve the medicine. In a statement notifying the ban, the ministry said the drug “is likely to involve risk to human beings and safer alternatives are available”. The drug has been used to treat breast cancer in...

India’s new vaccination policy stresses increased domestic research and surveillance on local diseases; but has drawn criticism for endorsing new vaccines in the national immunisation programme without ascertaining need. The April 2011 policy, made public by India’s ministry of health and family welfare in August, provides guidelines for vaccine research and development; strengthening the evidence base for new vaccine introduction and regulation and patent issues. It highlights lack of indigenous baseline surveillance...

Last month, the Archives of Internal Medicine published a scathing reassessment of a 12-year-old research study of Neurontin, a seizure drug made byPfizer. The study, which had included more than 2,700 subjects and was carried out by Parke-Davis (now part of Pfizer), was notable for how poorly it was conducted. The investigators were inexperienced and untrained, and the design of the study was so flawed it generated few if any...