In a major breakthrough Tuesday, researchers announced that the vaccine candidate RTS,S reduces the risk of malaria by half in children ages five to 17 months, first results from a continuing phase three trial showed. The results have tremendous implications, as malaria is responsible for nearly 800,000 deaths annually. The disease kills one child every 45 seconds in Africa, where it accounts for approximately 20 percent of childhood deaths, according to...

The Union health ministry today banned the manufacture and sale of a drug called letrozole to treat infertility in women, four years after its own drug regulators had waived safety studies and relaxed rules to approve the medicine. In a statement notifying the ban, the ministry said the drug “is likely to involve risk to human beings and safer alternatives are available”. The drug has been used to treat breast cancer in...

Last month, the Archives of Internal Medicine published a scathing reassessment of a 12-year-old research study of Neurontin, a seizure drug made byPfizer. The study, which had included more than 2,700 subjects and was carried out by Parke-Davis (now part of Pfizer), was notable for how poorly it was conducted. The investigators were inexperienced and untrained, and the design of the study was so flawed it generated few if any...

-The Hindu   Bill aims at making ethical committees looking into trials ‘robust' A legislation to monitor the entire research on human bodies by a single authority is likely to be introduced in the winter session of Parliament, according to V.M. Katoch, Secretary, Department of Health Research. The Bill will seek to make the ethical committees, presently looking into clinical trials on human beings, ‘robust' by constituting a monitoring mechanism over them. It was felt...

Poor Andhra villagers now victims of clinical Drug Trials No Drug Resistance     * 35 women, some men from Guntur district put throughclinical trials of a breast cancer drug. They later complain of joint pains, nausea and chest pains.     * Biotech industry in Andhra is worth about Rs 455 crore     * Touts operating on behalf of pharma companies get people from the poorer districts to Hyderabad for the tests *** Some 35 women...